| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the simvastatin-3002 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACVR1B | activin A receptor, type IB |
| ADORA3 | adenosine A3 receptor |
| AHSP | alpha hemoglobin stabilizing protein |
| APOD | apolipoprotein D |
| AREG | amphiregulin |
| ARL2BP | ADP-ribosylation factor-like 2 binding protein |
| ARTN | artemin |
| ATXN2L | ataxin 2-like |
| BCAS3 | breast carcinoma amplified sequence 3 |
| BCL2L10 | BCL2-like 10 (apoptosis facilitator) |
| BEND5 | BEN domain containing 5 |
| CALD1 | caldesmon 1 |
| CD163 | CD163 molecule |
| CD8B | CD8b molecule |
| CDO1 | cysteine dioxygenase type 1 |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 |
| CLDN14 | claudin 14 |
| CRABP2 | cellular retinoic acid binding protein 2 |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| DMTN | dematin actin binding protein |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP4 | dual specificity phosphatase 4 |
| EDN3 | endothelin 3 |
| ESR2 | estrogen receptor 2 (ER beta) |
| FAM120C | family with sequence similarity 120C |
| FAM198B | family with sequence similarity 198, member B |
| FDPS | farnesyl diphosphate synthase |
| FGF17 | fibroblast growth factor 17 |
| FKBP5 | FK506 binding protein 5 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 |
| FLT3 | fms-related tyrosine kinase 3 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GPR45 | G protein-coupled receptor 45 |
| GSPT1 | G1 to S phase transition 1 |
| GSTT1 | glutathione S-transferase theta 1 |
| HBB | hemoglobin, beta |
| HOXA10 | homeobox A10 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| HPSE2 | heparanase 2 (inactive) |
| IL1R2 | interleukin 1 receptor, type II |
| ITGB8 | integrin, beta 8 |
| ITPK1 | inositol-tetrakisphosphate 1-kinase |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
| KCNK10 | potassium channel, two pore domain subfamily K, member 10 |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| KLF12 | Kruppel-like factor 12 |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| MAPT | microtubule-associated protein tau |
| MARC1 | mitochondrial amidoxime reducing component 1 |
| METTL7A | methyltransferase like 7A |
| MMP19 | matrix metallopeptidase 19 |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MRPS12 | mitochondrial ribosomal protein S12 |
| MTCP1 | mature T-cell proliferation 1 |
| MYL10 | myosin, light chain 10, regulatory |
| NIPAL3 | NIPA-like domain containing 3 |
| NPR1 | natriuretic peptide receptor 1 |
| NPTX1 | neuronal pentraxin I |
| NRP2 | neuropilin 2 |
| NTN1 | netrin 1 |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PER1 | period circadian clock 1 |
| PI4KB | phosphatidylinositol 4-kinase, catalytic, beta |
| PIGR | polymeric immunoglobulin receptor |
| PTTG2 | pituitary tumor-transforming 2 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 |
| RBP4 | retinol binding protein 4, plasma |
| REG1A | regenerating islet-derived 1 alpha |
| RFPL2 | ret finger protein-like 2 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RHOB | ras homolog family member B |
| RHOH | ras homolog family member H |
| SDC2 | syndecan 2 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SLC23A2 | solute carrier family 23 (ascorbic acid transporter), member 2 |
| SORBS2 | sorbin and SH3 domain containing 2 |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| SYT1 | synaptotagmin I |
| TAPT1 | transmembrane anterior posterior transformation 1 |
| TBX2 | T-box 2 |
| THBS1 | thrombospondin 1 |
| TMEM257 | transmembrane protein 257 |
| TMOD1 | tropomodulin 1 |
| TNFSF18 | tumor necrosis factor (ligand) superfamily, member 18 |
| TONSL | tonsoku-like, DNA repair protein |
| TPM3 | tropomyosin 3 |
| TPST1 | tyrosylprotein sulfotransferase 1 |
| TRIM62 | tripartite motif containing 62 |
| TSC22D3 | TSC22 domain family, member 3 |
| TTLL3 | tubulin tyrosine ligase-like family member 3 |
| TUBA4B | tubulin, alpha 4b |
| ZBP1 | Z-DNA binding protein 1 |
| ZBTB16 | zinc finger and BTB domain containing 16 |
| ZNF646 | zinc finger protein 646 |
| Symbol | Name |
|---|---|
| ACPP | acid phosphatase, prostate |
| ADGB | androglobin |
| ANO2 | anoctamin 2, calcium activated chloride channel |
| APBB1IP | amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein |
| APOL6 | apolipoprotein L, 6 |
| ARG1 | arginase 1 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| BAG4 | BCL2-associated athanogene 4 |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C11ORF95 | chromosome 11 open reading frame 95 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C3 | complement component 3 |
| CCDC106 | coiled-coil domain containing 106 |
| CCDC71 | coiled-coil domain containing 71 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CCRL2 | chemokine (C-C motif) receptor-like 2 |
| CDK20 | cyclin-dependent kinase 20 |
| CFAP69 | cilia and flagella associated protein 69 |
| CNN1 | calponin 1, basic, smooth muscle |
| CST1 | cystatin SN |
| CTSV | cathepsin V |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| DNAL4 | dynein, axonemal, light chain 4 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| EPHB6 | EPH receptor B6 |
| FAM102A | family with sequence similarity 102, member A |
| FAM106A | family with sequence similarity 106, member A |
| FLRT1 | fibronectin leucine rich transmembrane protein 1 |
| GABRA4 | gamma-aminobutyric acid (GABA) A receptor, alpha 4 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GPATCH2L | G patch domain containing 2-like |
| GPC3 | glypican 3 |
| GRIP2 | glutamate receptor interacting protein 2 |
| HDAC7 | histone deacetylase 7 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HOXA2 | homeobox A2 |
| HOXC10 | homeobox C10 |
| HPSE | heparanase |
| HSPA1L | heat shock 70kDa protein 1-like |
| IBSP | integrin-binding sialoprotein |
| IFNA14 | interferon, alpha 14 |
| IFT140 | intraflagellar transport 140 |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIAA1107 | KIAA1107 |
| KRT12 | keratin 12, type I |
| MAGEB2 | melanoma antigen family B2 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 |
| MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
| MNS1 | meiosis-specific nuclear structural 1 |
| MTHFS | 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) |
| MXD3 | MAX dimerization protein 3 |
| NARFL | nuclear prelamin A recognition factor-like |
| NLK | nemo-like kinase |
| NMUR1 | neuromedin U receptor 1 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 |
| PBOV1 | prostate and breast cancer overexpressed 1 |
| PDE12 | phosphodiesterase 12 |
| PDZD7 | PDZ domain containing 7 |
| PIPOX | pipecolic acid oxidase |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma |
| PPM1E | protein phosphatase, Mg2+/Mn2+ dependent, 1E |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRSS53 | protease, serine, 53 |
| PYGB | phosphorylase, glycogen; brain |
| RAPSN | receptor-associated protein of the synapse |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SHPK | sedoheptulokinase |
| SKI | SKI proto-oncogene |
| SLC16A4 | solute carrier family 16, member 4 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SLC35F6 | solute carrier family 35, member F6 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SPATA2L | spermatogenesis associated 2-like |
| SRD5A2 | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
| TESPA1 | thymocyte expressed, positive selection associated 1 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 |
| TMEM140 | transmembrane protein 140 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TRIM36 | tripartite motif containing 36 |
| UBQLN4 | ubiquilin 4 |
| UPB1 | ureidopropionase, beta |
| WASF3 | WAS protein family, member 3 |
| ZNF324 | zinc finger protein 324 |
| ZNF415 | zinc finger protein 415 |
| ZNF675 | zinc finger protein 675 |
| ZNF749 | zinc finger protein 749 |
