| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the simvastatin-3340 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ABHD17B | abhydrolase domain containing 17B |
| ADCY3 | adenylate cyclase 3 |
| AKAP4 | A kinase (PRKA) anchor protein 4 |
| ANTXR1 | anthrax toxin receptor 1 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| ATF3 | activating transcription factor 3 |
| BCAP29 | B-cell receptor-associated protein 29 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| CLCA1 | chloride channel accessory 1 |
| CLIC5 | chloride intracellular channel 5 |
| CNPY4 | canopy FGF signaling regulator 4 |
| CNTN5 | contactin 5 |
| COL1A1 | collagen, type I, alpha 1 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) |
| COL5A2 | collagen, type V, alpha 2 |
| COLEC10 | collectin sub-family member 10 (C-type lectin) |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| DEAF1 | DEAF1 transcription factor |
| DES | desmin |
| DMRT1 | doublesex and mab-3 related transcription factor 1 |
| DNALI1 | dynein, axonemal, light intermediate chain 1 |
| DOCK9 | dedicator of cytokinesis 9 |
| DOK4 | docking protein 4 |
| EFNB3 | ephrin-B3 |
| EGR1 | early growth response 1 |
| EPHB2 | EPH receptor B2 |
| FGFR3 | fibroblast growth factor receptor 3 |
| FOSL2 | FOS-like antigen 2 |
| GABARAPL3 | GABA(A) receptors associated protein like 3, pseudogene |
| GNAS | GNAS complex locus |
| GPR182 | G protein-coupled receptor 182 |
| GPR22 | G protein-coupled receptor 22 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| HIST1H3B | histone cluster 1, H3b |
| HOXA10 | homeobox A10 |
| HOXB2 | homeobox B2 |
| HTR1A | 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IDS | iduronate 2-sulfatase |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| INHA | inhibin, alpha |
| ISG20L2 | interferon stimulated exonuclease gene 20kDa-like 2 |
| ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) |
| ITGB4 | integrin, beta 4 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KIAA0391 | KIAA0391 |
| KIAA1324 | KIAA1324 |
| KLF6 | Kruppel-like factor 6 |
| KLHL22 | kelch-like family member 22 |
| KRT15 | keratin 15, type I |
| LMO3 | LIM domain only 3 (rhombotin-like 2) |
| MEF2D | myocyte enhancer factor 2D |
| MIR622 | microRNA 622 |
| MYOC | myocilin, trabecular meshwork inducible glucocorticoid response |
| NDRG2 | NDRG family member 2 |
| NF1 | neurofibromin 1 |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NME5 | NME/NM23 family member 5 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| P2RY4 | pyrimidinergic receptor P2Y, G-protein coupled, 4 |
| PCDH1 | protocadherin 1 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PER1 | period circadian clock 1 |
| PIGR | polymeric immunoglobulin receptor |
| PLLP | plasmolipin |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRDX2 | peroxiredoxin 2 |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| PVRL1 | poliovirus receptor-related 1 (herpesvirus entry mediator C) |
| RAB3B | RAB3B, member RAS oncogene family |
| RAB6B | RAB6B, member RAS oncogene family |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RPL35A | ribosomal protein L35a |
| SBNO1 | strawberry notch homolog 1 (Drosophila) |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SLC1A2 | solute carrier family 1 (glial high affinity glutamate transporter), member 2 |
| SLC2A9 | solute carrier family 2 (facilitated glucose transporter), member 9 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| SPRED2 | sprouty-related, EVH1 domain containing 2 |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| SSTR5 | somatostatin receptor 5 |
| SUGP1 | SURP and G patch domain containing 1 |
| TBCD | tubulin folding cofactor D |
| TFEB | transcription factor EB |
| TKTL1 | transketolase-like 1 |
| TRIM38 | tripartite motif containing 38 |
| WSCD1 | WSC domain containing 1 |
| XYLT1 | xylosyltransferase I |
| Symbol | Name |
|---|---|
| AARSD1 | alanyl-tRNA synthetase domain containing 1 |
| ABLIM3 | actin binding LIM protein family, member 3 |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| AFF4 | AF4/FMR2 family, member 4 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ARL15 | ADP-ribosylation factor-like 15 |
| ARMC6 | armadillo repeat containing 6 |
| ARMCX2 | armadillo repeat containing, X-linked 2 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BATF | basic leucine zipper transcription factor, ATF-like |
| C5AR2 | complement component 5a receptor 2 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CCNK | cyclin K |
| CCNL2 | cyclin L2 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CEP97 | centrosomal protein 97kDa |
| CYP4F12 | cytochrome P450, family 4, subfamily F, polypeptide 12 |
| DUSP2 | dual specificity phosphatase 2 |
| EDAR | ectodysplasin A receptor |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| F2R | coagulation factor II (thrombin) receptor |
| FAIM | Fas apoptotic inhibitory molecule |
| FAM186A | family with sequence similarity 186, member A |
| FER | fer (fps/fes related) tyrosine kinase |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GBAS | glioblastoma amplified sequence |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GMPR | guanosine monophosphate reductase |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HIST1H2AI | histone cluster 1, H2ai |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HMGB3P1 | high mobility group box 3 pseudogene 1 |
| IL22 | interleukin 22 |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| IPO8 | importin 8 |
| IQCG | IQ motif containing G |
| JUNB | jun B proto-oncogene |
| KDM5C | lysine (K)-specific demethylase 5C |
| KDM7A | lysine (K)-specific demethylase 7A |
| KLHL36 | kelch-like family member 36 |
| LHX1 | LIM homeobox 1 |
| LIN7B | lin-7 homolog B (C. elegans) |
| LMNB1 | lamin B1 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MAP9 | microtubule-associated protein 9 |
| MTERF1 | mitochondrial transcription termination factor 1 |
| MXD3 | MAX dimerization protein 3 |
| NLRX1 | NLR family member X1 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NPY1R | neuropeptide Y receptor Y1 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| NXPH4 | neurexophilin 4 |
| PCBP4 | poly(rC) binding protein 4 |
| PCDHA6 | protocadherin alpha 6 |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PITX2 | paired-like homeodomain 2 |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PODXL2 | podocalyxin-like 2 |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| RAB3A | RAB3A, member RAS oncogene family |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPL10L | ribosomal protein L10-like |
| SDC3 | syndecan 3 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SH2B3 | SH2B adaptor protein 3 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SMS | spermine synthase |
| SND1-IT1 | SND1 intronic transcript 1 |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 |
| THRB | thyroid hormone receptor, beta |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM120B | transmembrane protein 120B |
| TMEM121 | transmembrane protein 121 |
| TRIM36 | tripartite motif containing 36 |
| TTF2 | transcription termination factor, RNA polymerase II |
| TUBA3D | tubulin, alpha 3d |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| USB1 | U6 snRNA biogenesis 1 |
| VLDLR | very low density lipoprotein receptor |
| WDR33 | WD repeat domain 33 |
| WDR91 | WD repeat domain 91 |
| XDH | xanthine dehydrogenase |
| XYLT2 | xylosyltransferase II |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZNF205 | zinc finger protein 205 |
| ZNF273 | zinc finger protein 273 |
| ZNF358 | zinc finger protein 358 |
| ZNF573 | zinc finger protein 573 |
| ZNF675 | zinc finger protein 675 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |
