| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the simvastatin-4244 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 |
| AHNAK | AHNAK nucleoprotein |
| AMPD1 | adenosine monophosphate deaminase 1 |
| ANGPT1 | angiopoietin 1 |
| ANGPTL4 | angiopoietin-like 4 |
| APAF1 | apoptotic peptidase activating factor 1 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARHGAP28 | Rho GTPase activating protein 28 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 |
| BCL2L11 | BCL2-like 11 (apoptosis facilitator) |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C1S | complement component 1, s subcomponent |
| CCL23 | chemokine (C-C motif) ligand 23 |
| CD226 | CD226 molecule |
| CDC14A | cell division cycle 14A |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CITED1 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 |
| CNGA1 | cyclic nucleotide gated channel alpha 1 |
| CYSLTR2 | cysteinyl leukotriene receptor 2 |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DMBT1 | deleted in malignant brain tumors 1 |
| DUSP1 | dual specificity phosphatase 1 |
| EGR1 | early growth response 1 |
| EXOSC2 | exosome component 2 |
| EZR | ezrin |
| FLOT1 | flotillin 1 |
| FRMD4B | FERM domain containing 4B |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPR161 | G protein-coupled receptor 161 |
| GRIA3 | glutamate receptor, ionotropic, AMPA 3 |
| GYPB | glycophorin B (MNS blood group) |
| HAP1 | huntingtin-associated protein 1 |
| HCN4 | hyperpolarization activated cyclic nucleotide gated potassium channel 4 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| IGFBP7 | insulin-like growth factor binding protein 7 |
| IL1RN | interleukin 1 receptor antagonist |
| INE1 | inactivation escape 1 (non-protein coding) |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KLF2 | Kruppel-like factor 2 |
| KLF6 | Kruppel-like factor 6 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| KRT6A | keratin 6A, type II |
| LDB3 | LIM domain binding 3 |
| LEPR | leptin receptor |
| LIG3 | ligase III, DNA, ATP-dependent |
| LILRA1 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 |
| LMTK2 | lemur tyrosine kinase 2 |
| MAN2A2 | mannosidase, alpha, class 2A, member 2 |
| MAPK10 | mitogen-activated protein kinase 10 |
| MARK1 | MAP/microtubule affinity-regulating kinase 1 |
| METTL7A | methyltransferase like 7A |
| MT1F | metallothionein 1F |
| MT1X | metallothionein 1X |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming |
| NBR2 | neighbor of BRCA1 gene 2 (non-protein coding) |
| NCOA3 | nuclear receptor coactivator 3 |
| NDNF | neuron-derived neurotrophic factor |
| NME5 | NME/NM23 family member 5 |
| NOV | nephroblastoma overexpressed |
| OBSL1 | obscurin-like 1 |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PECAM1 | platelet/endothelial cell adhesion molecule 1 |
| PER1 | period circadian clock 1 |
| PKP4 | plakophilin 4 |
| PML | promyelocytic leukemia |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 |
| PRR5 | proline rich 5 (renal) |
| PTGES | prostaglandin E synthase |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 |
| RGS5 | regulator of G-protein signaling 5 |
| RHOB | ras homolog family member B |
| RIMS2 | regulating synaptic membrane exocytosis 2 |
| RPL10L | ribosomal protein L10-like |
| RUNX1 | runt-related transcription factor 1 |
| S100P | S100 calcium binding protein P |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 |
| SLC2A11 | solute carrier family 2 (facilitated glucose transporter), member 11 |
| SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STK17A | serine/threonine kinase 17a |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| THTPA | thiamine triphosphatase |
| TLR1 | toll-like receptor 1 |
| TNIK | TRAF2 and NCK interacting kinase |
| TRIM29 | tripartite motif containing 29 |
| TSC22D2 | TSC22 domain family, member 2 |
| VAMP5 | vesicle-associated membrane protein 5 |
| VNN2 | vanin 2 |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase |
| ZNF141 | zinc finger protein 141 |
| Symbol | Name |
|---|---|
| ALOX12 | arachidonate 12-lipoxygenase |
| ANXA2P1 | annexin A2 pseudogene 1 |
| ARRB2 | arrestin, beta 2 |
| AXIN1 | axin 1 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| C14ORF105 | chromosome 14 open reading frame 105 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| C5ORF42 | chromosome 5 open reading frame 42 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CBX8 | chromobox homolog 8 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CCNO | cyclin O |
| CCNT1 | cyclin T1 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CD68 | CD68 molecule |
| CD82 | CD82 molecule |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CDHR2 | cadherin-related family member 2 |
| CLCA1 | chloride channel accessory 1 |
| CLDN1 | claudin 1 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| CNOT3 | CCR4-NOT transcription complex, subunit 3 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 |
| CRABP2 | cellular retinoic acid binding protein 2 |
| CXCR2 | chemokine (C-X-C motif) receptor 2 |
| CXORF21 | chromosome X open reading frame 21 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EFCAB2 | EF-hand calcium binding domain 2 |
| EFHD2 | EF-hand domain family, member D2 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi |
| GBX2 | gastrulation brain homeobox 2 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HAMP | hepcidin antimicrobial peptide |
| HIST1H2BN | histone cluster 1, H2bn |
| IL36RN | interleukin 36 receptor antagonist |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KDM8 | lysine (K)-specific demethylase 8 |
| KRT34 | keratin 34, type I |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LMO7 | LIM domain 7 |
| LPAR4 | lysophosphatidic acid receptor 4 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MTSS1L | metastasis suppressor 1-like |
| MX1 | MX dynamin-like GTPase 1 |
| MYL9 | myosin, light chain 9, regulatory |
| MYO1F | myosin IF |
| NAALAD2 | N-acetylated alpha-linked acidic dipeptidase 2 |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NPFFR1 | neuropeptide FF receptor 1 |
| ODF2 | outer dense fiber of sperm tails 2 |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| PALM | paralemmin |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PDE12 | phosphodiesterase 12 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) |
| PLBD1 | phospholipase B domain containing 1 |
| POLL | polymerase (DNA directed), lambda |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRM2 | protamine 2 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RAPSN | receptor-associated protein of the synapse |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RNF2 | ring finger protein 2 |
| ROGDI | rogdi homolog (Drosophila) |
| RUNX1-IT1 | RUNX1 intronic transcript 1 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCAMP4 | secretory carrier membrane protein 4 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SLCO1B1 | solute carrier organic anion transporter family, member 1B1 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SORBS3 | sorbin and SH3 domain containing 3 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SP1 | Sp1 transcription factor |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| SSBP3 | single stranded DNA binding protein 3 |
| STK16 | serine/threonine kinase 16 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TBC1D22B | TBC1 domain family, member 22B |
| TNFSF15 | tumor necrosis factor (ligand) superfamily, member 15 |
| TSC22D4 | TSC22 domain family, member 4 |
| UGT8 | UDP glycosyltransferase 8 |
| USP20 | ubiquitin specific peptidase 20 |
| WNT1 | wingless-type MMTV integration site family, member 1 |
| ZNF254 | zinc finger protein 254 |
| ZYX | zyxin |
