| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the simvastatin-4828 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) |
| ACO2 | aconitase 2, mitochondrial |
| ADD2 | adducin 2 (beta) |
| ADORA1 | adenosine A1 receptor |
| AKAP11 | A kinase (PRKA) anchor protein 11 |
| ALOX15 | arachidonate 15-lipoxygenase |
| AP5Z1 | adaptor-related protein complex 5, zeta 1 subunit |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| ATP10B | ATPase, class V, type 10B |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| BAIAP2 | BAI1-associated protein 2 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CALCR | calcitonin receptor |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CDHR2 | cadherin-related family member 2 |
| CDK6 | cyclin-dependent kinase 6 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 |
| CFAP45 | cilia and flagella associated protein 45 |
| CHAT | choline O-acetyltransferase |
| CHST3 | carbohydrate (chondroitin 6) sulfotransferase 3 |
| COL19A1 | collagen, type XIX, alpha 1 |
| COL1A1 | collagen, type I, alpha 1 |
| CRAT | carnitine O-acetyltransferase |
| CUL9 | cullin 9 |
| CYLC1 | cylicin, basic protein of sperm head cytoskeleton 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DBN1 | drebrin 1 |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DLC1 | DLC1 Rho GTPase activating protein |
| DOK5 | docking protein 5 |
| EFR3B | EFR3 homolog B (S. cerevisiae) |
| EGR1 | early growth response 1 |
| EPN1 | epsin 1 |
| F12 | coagulation factor XII (Hageman factor) |
| FAM212B | family with sequence similarity 212, member B |
| FKBP8 | FK506 binding protein 8, 38kDa |
| FLI1 | Fli-1 proto-oncogene, ETS transcription factor |
| GAS7 | growth arrest-specific 7 |
| GGT1 | gamma-glutamyltransferase 1 |
| GPATCH2L | G patch domain containing 2-like |
| GPR157 | G protein-coupled receptor 157 |
| GRAP | GRB2-related adaptor protein |
| HCRP1 | hepatocellular carcinoma-related HCRP1 |
| HIST1H1T | histone cluster 1, H1t |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| HSF1 | heat shock transcription factor 1 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFT27 | intraflagellar transport 27 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| IL17RC | interleukin 17 receptor C |
| KCNJ3 | potassium channel, inwardly rectifying subfamily J, member 3 |
| KLF2 | Kruppel-like factor 2 |
| KLK13 | kallikrein-related peptidase 13 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MED18 | mediator complex subunit 18 |
| MEGF6 | multiple EGF-like-domains 6 |
| MSI1 | musashi RNA-binding protein 1 |
| MST1R | macrophage stimulating 1 receptor |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist |
| PHC3 | polyhomeotic homolog 3 (Drosophila) |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PLN | phospholamban |
| PML | promyelocytic leukemia |
| POLM | polymerase (DNA directed), mu |
| RAB36 | RAB36, member RAS oncogene family |
| RASAL2 | RAS protein activator like 2 |
| RPL35A | ribosomal protein L35a |
| RTN2 | reticulon 2 |
| SERHL2 | serine hydrolase-like 2 |
| SH3BP2 | SH3-domain binding protein 2 |
| SH3GL3 | SH3-domain GRB2-like 3 |
| SMTN | smoothelin |
| SNPH | syntaphilin |
| SPN | sialophorin |
| TBC1D17 | TBC1 domain family, member 17 |
| TBX5 | T-box 5 |
| TGFBR1 | transforming growth factor, beta receptor 1 |
| TM2D1 | TM2 domain containing 1 |
| TM4SF5 | transmembrane 4 L six family member 5 |
| TMC6 | transmembrane channel-like 6 |
| TOP3A | topoisomerase (DNA) III alpha |
| TRIB2 | tribbles pseudokinase 2 |
| TRIM29 | tripartite motif containing 29 |
| WNK1 | WNK lysine deficient protein kinase 1 |
| WWOX | WW domain containing oxidoreductase |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF442 | zinc finger protein 442 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ACYP1 | acylphosphatase 1, erythrocyte (common) type |
| ADCY6 | adenylate cyclase 6 |
| AKTIP | AKT interacting protein |
| ANAPC10 | anaphase promoting complex subunit 10 |
| ANKRD36 | ankyrin repeat domain 36 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| BAGE | B melanoma antigen |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| CASP8AP2 | caspase 8 associated protein 2 |
| CBR4 | carbonyl reductase 4 |
| CDC7 | cell division cycle 7 |
| CENPQ | centromere protein Q |
| CLDND1 | claudin domain containing 1 |
| COCH | cochlin |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CRYZL1 | crystallin, zeta (quinone reductase)-like 1 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DENND4A | DENN/MADD domain containing 4A |
| DNAJC13 | DnaJ (Hsp40) homolog, subfamily C, member 13 |
| DTWD1 | DTW domain containing 1 |
| DUSP2 | dual specificity phosphatase 2 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EFCAB2 | EF-hand calcium binding domain 2 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| ETNK2 | ethanolamine kinase 2 |
| FAM184A | family with sequence similarity 184, member A |
| FBXO22 | F-box protein 22 |
| FCHSD2 | FCH and double SH3 domains 2 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 |
| FZD3 | frizzled class receptor 3 |
| GID4 | GID complex subunit 4 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GSTA4 | glutathione S-transferase alpha 4 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HIST1H2AL | histone cluster 1, H2al |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
| ICK | intestinal cell (MAK-like) kinase |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA0355 | KIAA0355 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MANEA | mannosidase, endo-alpha |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MEFV | Mediterranean fever |
| MINPP1 | multiple inositol-polyphosphate phosphatase 1 |
| NIPAL2 | NIPA-like domain containing 2 |
| NPY1R | neuropeptide Y receptor Y1 |
| NUBPL | nucleotide binding protein-like |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| POLR3F | polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| RECQL4 | RecQ protein-like 4 |
| RNF146 | ring finger protein 146 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RP2 | retinitis pigmentosa 2 (X-linked recessive) |
| SCAI | suppressor of cancer cell invasion |
| SECISBP2 | SECIS binding protein 2 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SPAG1 | sperm associated antigen 1 |
| SPC25 | SPC25, NDC80 kinetochore complex component |
| SYTL2 | synaptotagmin-like 2 |
| TBC1D19 | TBC1 domain family, member 19 |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TMEM184B | transmembrane protein 184B |
| TMEM184C | transmembrane protein 184C |
| TMEM2 | transmembrane protein 2 |
| TRIM5 | tripartite motif containing 5 |
| TTC17 | tetratricopeptide repeat domain 17 |
| TWF2 | twinfilin actin binding protein 2 |
| VEGFC | vascular endothelial growth factor C |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) |
| WRN | Werner syndrome, RecQ helicase-like |
| XK | X-linked Kx blood group |
| ZFYVE16 | zinc finger, FYVE domain containing 16 |
| ZNF143 | zinc finger protein 143 |
| ZNF226 | zinc finger protein 226 |
| ZNF280D | zinc finger protein 280D |
| ZNF329 | zinc finger protein 329 |
| ZNF652 | zinc finger protein 652 |
| ZNF747 | zinc finger protein 747 |
| ZNF813 | zinc finger protein 813 |
| ZNF816 | zinc finger protein 816 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
