sin3 complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A multiprotein complex that functions broadly in eukaryotic organisms as a transcriptional repressor of protein-coding genes, through the gene-specific deacetylation of histones. Amongst its subunits, the Sin3 complex contains Sin3-like proteins, and a number of core proteins that are shared with the NuRD complex (including histone deacetylases and histone binding proteins). The Sin3 complex does not directly bind DNA itself, but is targeted to specific genes through protein-protein interactions with DNA-binding proteins. (Gene Ontology, GO_0016580)
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Genes

21 proteins co-occuring with the sin3 complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
FAM60A family with sequence similarity 60, member A 1.4791
SUDS3 suppressor of defective silencing 3 homolog (S. cerevisiae) 1.4757
SAP18 Sin3A-associated protein, 18kDa 1.46382
SIN3A SIN3 transcription regulator family member A 1.26921
SAP30 Sin3A-associated protein, 30kDa 1.12552
HDAC9 histone deacetylase 9 1.08222
HDAC2 histone deacetylase 2 1.03479
HDAC10 histone deacetylase 10 1.02879
SIN3B SIN3 transcription regulator family member B 0.943533
ING2 inhibitor of growth family, member 2 0.929833
MXI1 MAX interactor 1, dimerization protein 0.918111
ING3 inhibitor of growth family, member 3 0.857095
HDAC1 histone deacetylase 1 0.840564
ING1 inhibitor of growth family, member 1 0.752716
RBBP4 retinoblastoma binding protein 4 0.665529
E2F4 E2F transcription factor 4, p107/p130-binding 0.603174
HDAC6 histone deacetylase 6 0.37505
SP1 Sp1 transcription factor 0.341907
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.233101
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.165932
BIRC5 baculoviral IAP repeat containing 5 0.158692