sinusitis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A paranasal sinus disease involving inflammation of the paranasal sinuses resulting from bacterial, fungal, viral infection, allergic or autoimmune issues. Symptoms can include fever, weakness, fatigue, cough and congestion. There may also be mucus drainage in the back of the throat, called postnasal drip. (Human Disease Ontology, DOID_0050127)
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Genes

221 genes co-occuring with the disease sinusitis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
PDZD11 PDZ domain containing 11 1.46627
FLNC filamin C, gamma 1.461
OAF OAF homolog (Drosophila) 1.42586
PRTN3 proteinase 3 1.35725
HTRA3 HtrA serine peptidase 3 1.33589
CD79A CD79a molecule, immunoglobulin-associated alpha 1.28523
MUC5B mucin 5B, oligomeric mucus/gel-forming 1.2382
CD4 CD4 molecule 1.20007
BPIFA1 BPI fold containing family A, member 1 1.1755
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 1.10931
DCXR dicarbonyl/L-xylulose reductase 1.05639
IL5 interleukin 5 1.02271
SPEF2 sperm flagellar 2 0.994017
KRTAP1-3 keratin associated protein 1-3 0.97128
KRTAP1-1 keratin associated protein 1-1 0.97128
BTK Bruton agammaglobulinemia tyrosine kinase 0.940364
IL1B interleukin 1, beta 0.917611
MS4A2 membrane-spanning 4-domains, subfamily A, member 2 0.904442
CXCL8 chemokine (C-X-C motif) ligand 8 0.897872
HSF4 heat shock transcription factor 4 0.881472
RNASE3 ribonuclease, RNase A family, 3 0.864684
CRP C-reactive protein, pentraxin-related 0.856905
PRAMEF10 PRAME family member 10 0.849945
MUC2 mucin 2, oligomeric mucus/gel-forming 0.836837
TNF tumor necrosis factor 0.832738
DPCD deleted in primary ciliary dyskinesia homolog (mouse) 0.81018
LYZ lysozyme 0.788033
DNAH11 dynein, axonemal, heavy chain 11 0.785574
DEFB4A defensin, beta 4A 0.76431
MPO myeloperoxidase 0.745578
CXCL6 chemokine (C-X-C motif) ligand 6 0.743954
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.736243
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 0.719654
PKD1L1 polycystic kidney disease 1 like 1 0.703536
ZRANB2 zinc finger, RAN-binding domain containing 2 0.695103
BRI3 brain protein I3 0.691094
CPLX4 complexin 4 0.680697
TRIM39 tripartite motif containing 39 0.679499
CCL17 chemokine (C-C motif) ligand 17 0.65763
LTC4S leukotriene C4 synthase 0.650113
DNAI1 dynein, axonemal, intermediate chain 1 0.646559
DEFB1 defensin, beta 1 0.63907
NME7 NME/NM23 family member 7 0.638282
SCYL1 SCY1-like 1 (S. cerevisiae) 0.636708
ELANE elastase, neutrophil expressed 0.634349
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 0.617486
FLNA filamin A, alpha 0.612792
LTF lactotransferrin 0.60108
CXCL5 chemokine (C-X-C motif) ligand 5 0.60069
TERF2 telomeric repeat binding factor 2 0.591337
CD209 CD209 molecule 0.588612
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.584719
MUC7 mucin 7, secreted 0.581996
ICAM1 intercellular adhesion molecule 1 0.580828
IL4 interleukin 4 0.578883
SPAG16 sperm associated antigen 16 0.574605
MFSD10 major facilitator superfamily domain containing 10 0.561392
DNAH5 dynein, axonemal, heavy chain 5 0.556344
AK7 adenylate kinase 7 0.541605
CAMP cathelicidin antimicrobial peptide 0.539667
METAP2 methionyl aminopeptidase 2 0.535796
CTC1 CTS telomere maintenance complex component 1 0.529608
ALB albumin 0.524588
CCL13 chemokine (C-C motif) ligand 13 0.52343
AOAH acyloxyacyl hydrolase (neutrophil) 0.521502
SEPT2 septin 2 0.519575
MED28 mediator complex subunit 28 0.514571
DNAI2 dynein, axonemal, intermediate chain 2 0.508041
CCL11 chemokine (C-C motif) ligand 11 0.495029
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 0.493885
DNASE1 deoxyribonuclease I 0.481325
PDLIM2 PDZ and LIM domain 2 (mystique) 0.481325
PRRC2A proline-rich coiled-coil 2A 0.480566
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.47753
CYSLTR2 cysteinyl leukotriene receptor 2 0.476014
C1ORF167 chromosome 1 open reading frame 167 0.472982
VCAM1 vascular cell adhesion molecule 1 0.466928
CD19 CD19 molecule 0.46466
EMC3 ER membrane protein complex subunit 3 0.461639
TUBE1 tubulin, epsilon 1 0.460506
TLR2 toll-like receptor 2 0.458996
SEPT11 septin 11 0.454847
LAMB1 laminin, beta 1 0.449571
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.446182
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.445805
ZCCHC7 zinc finger, CCHC domain containing 7 0.445052
NPS neuropeptide S 0.43753
PPP1R9B protein phosphatase 1, regulatory subunit 9B 0.433772
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 0.427015
PLG plasminogen 0.425514
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.424014
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 0.420266
DYNLT1 dynein, light chain, Tctex-type 1 0.419517
UNC119 unc-119 homolog (C. elegans) 0.416521
SIGLEC8 sialic acid binding Ig-like lectin 8 0.411283
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 0.407172
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit 0.406051
MRO maestro 0.404184
SOD2 superoxide dismutase 2, mitochondrial 0.402318
WDFY2 WD repeat and FYVE domain containing 2 0.394863
CD68 CD68 molecule 0.394491
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16 0.374068
NCAM1 neural cell adhesion molecule 1 0.370368
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.369628
TLR4 toll-like receptor 4 0.364824
CAT catalase 0.359657
MGP matrix Gla protein 0.358551
IGLV9-49 immunoglobulin lambda variable 9-49 0.345308
IL1A interleukin 1, alpha 0.343106
JUN jun proto-oncogene 0.342372
SELE selectin E 0.340539
NCOA1 nuclear receptor coactivator 1 0.336876
IL3 interleukin 3 0.328469
CSF3 colony stimulating factor 3 (granulocyte) 0.322273
DEFA5 defensin, alpha 5, Paneth cell-specific 0.321545
POMC proopiomelanocortin 0.317545
FOXJ1 forkhead box J1 0.315366
RARS arginyl-tRNA synthetase 0.305587
IL13RA1 interleukin 13 receptor, alpha 1 0.302698
CDON cell adhesion associated, oncogene regulated 0.301615
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.300173
CCR3 chemokine (C-C motif) receptor 3 0.287952
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 0.287593
POSTN periostin, osteoblast specific factor 0.286519
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.284013
OCM2 oncomodulin 2 0.277584
IL6 interleukin 6 0.272953
PPIG peptidylprolyl isomerase G (cyclophilin G) 0.267622
NT5C2 5'-nucleotidase, cytosolic II 0.26266
DNAH9 dynein, axonemal, heavy chain 9 0.261952
OCM oncomodulin 0.260538
FAP fibroblast activation protein, alpha 0.25877
DPEP1 dipeptidase 1 (renal) 0.255594
SMC1A structural maintenance of chromosomes 1A 0.253831
IFNG interferon, gamma 0.247852
PDE5A phosphodiesterase 5A, cGMP-specific 0.246098
POLB polymerase (DNA directed), beta 0.243295
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 0.241895
GPX5 glutathione peroxidase 5 0.240847
AADACL3 arylacetamide deacetylase-like 3 0.240497
SUMF2 sulfatase modifying factor 2 0.238403
GPX4 glutathione peroxidase 4 0.238054
HES4 hes family bHLH transcription factor 4 0.235616
RENBP renin binding protein 0.235268
MUC4 mucin 4, cell surface associated 0.234225
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.232142
GPX1 glutathione peroxidase 1 0.223853
CD80 CD80 molecule 0.215992
HLA-C major histocompatibility complex, class I, C 0.214636
POLL polymerase (DNA directed), lambda 0.213283
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8 0.212945
TGFB1 transforming growth factor, beta 1 0.210253
NCF1C neutrophil cytosolic factor 1C pseudogene 0.208579
NPTN neuroplastin 0.208245
EPX eosinophil peroxidase 0.205916
CD248 CD248 molecule, endosialin 0.204593
GM2A GM2 ganglioside activator 0.20229
MAPK14 mitogen-activated protein kinase 14 0.200331
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 0.197742
RD3 retinal degeneration 3 0.195501
KIF21A kinesin family member 21A 0.195183
MTSS1 metastasis suppressor 1 0.193285
PGRMC1 progesterone receptor membrane component 1 0.192657
IGLV3-10 immunoglobulin lambda variable 3-10 0.191719
CD99 CD99 molecule 0.189859
MMP9 matrix metallopeptidase 9 0.188326
DOCK8 dedicator of cytokinesis 8 0.185612
RING1 ring finger protein 1 0.185016
CARD9 caspase recruitment domain family, member 9 0.184424
OR2AG1 olfactory receptor, family 2, subfamily AG, member 1 (gene/pseudogene) 0.18151
HRH1 histamine receptor H1 0.180937
ACE angiotensin I converting enzyme 0.178682
LAMP3 lysosomal-associated membrane protein 3 0.177301
NCF1 neutrophil cytosolic factor 1 0.176757
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 0.175679
TUB tubby bipartite transcription factor 0.174093
KRT13 keratin 13, type I 0.173832
GCLM glutamate-cysteine ligase, modifier subunit 0.173832
CYS1 cystin 1 0.173571
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5 0.170789
IL1R2 interleukin 1 receptor, type II 0.169812
ACOT13 acyl-CoA thioesterase 13 0.166768
ALOX15 arachidonate 15-lipoxygenase 0.166095
NKX6-2 NK6 homeobox 2 0.165655
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 0.164149
CD86 CD86 molecule 0.163729
IL2RA interleukin 2 receptor, alpha 0.163317
CLCN3 chloride channel, voltage-sensitive 3 0.163111
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 0.163111
GNS glucosamine (N-acetyl)-6-sulfatase 0.161523
CLNK cytokine-dependent hematopoietic cell linker 0.160761
TBXA2R thromboxane A2 receptor 0.160761
LY75 lymphocyte antigen 75 0.158951
CDK11A cyclin-dependent kinase 11A 0.158434
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4 0.157602
GOLPH3 golgi phosphoprotein 3 (coat-protein) 0.143296
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 0.143144
MAEA macrophage erythroblast attacher 0.142829
MUC6 mucin 6, oligomeric mucus/gel-forming 0.142118
GYPA glycophorin A (MNS blood group) 0.140788
GAS6 growth arrest-specific 6 0.139738
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 0.137647
MUC1 mucin 1, cell surface associated 0.137271
LDHA lactate dehydrogenase A 0.135675
IRF6 interferon regulatory factor 6 0.134927
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 0.13364
GJB6 gap junction protein, beta 6, 30kDa 0.131002
PDPN podoplanin 0.129318
F9 coagulation factor IX 0.128632
KMT2A lysine (K)-specific methyltransferase 2A 0.12714
AVP arginine vasopressin 0.114165
CTRL chymotrypsin-like 0.10431
C4A complement component 4A (Rodgers blood group) 0.10221
FTL ferritin, light polypeptide 0.099822
FTH1 ferritin, heavy polypeptide 1 0.099789
TAC1 tachykinin, precursor 1 0.099034
SYP synaptophysin 0.095882
UPK2 uroplakin 2 0.088619
C5AR1 complement component 5a receptor 1 0.087314
F8 coagulation factor VIII, procoagulant component 0.084254
ASRGL1 asparaginase like 1 0.081684