| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the sirolimus-1001 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADAP1 | ArfGAP with dual PH domains 1 |
| ADCK3 | aarF domain containing kinase 3 |
| APOL2 | apolipoprotein L, 2 |
| ATP9A | ATPase, class II, type 9A |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C17ORF59 | chromosome 17 open reading frame 59 |
| CALHM2 | calcium homeostasis modulator 2 |
| CCDC28A | coiled-coil domain containing 28A |
| CCNG2 | cyclin G2 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CYLC1 | cylicin, basic protein of sperm head cytoskeleton 1 |
| DIXDC1 | DIX domain containing 1 |
| DSTYK | dual serine/threonine and tyrosine protein kinase |
| EFNB3 | ephrin-B3 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| FAM63A | family with sequence similarity 63, member A |
| FAM63B | family with sequence similarity 63, member B |
| FLJ11292 | |
| FRMD4A | FERM domain containing 4A |
| GLIPR1 | GLI pathogenesis-related 1 |
| GM2A | GM2 ganglioside activator |
| GPC4 | glypican 4 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) |
| GPR87 | G protein-coupled receptor 87 |
| GRB7 | growth factor receptor-bound protein 7 |
| HBP1 | HMG-box transcription factor 1 |
| HBS1L | HBS1-like translational GTPase |
| INADL | InaD-like (Drosophila) |
| ING4 | inhibitor of growth family, member 4 |
| INO80D | INO80 complex subunit D |
| KAZALD1 | Kazal-type serine peptidase inhibitor domain 1 |
| KIAA0141 | KIAA0141 |
| KLF2 | Kruppel-like factor 2 |
| KLHL24 | kelch-like family member 24 |
| LOC644450 | uncharacterized LOC644450 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| LYRM9 | LYR motif containing 9 |
| LZTFL1 | leucine zipper transcription factor-like 1 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAPK8 | mitogen-activated protein kinase 8 |
| METTL5 | methyltransferase like 5 |
| MTAP | methylthioadenosine phosphorylase |
| MXD3 | MAX dimerization protein 3 |
| MXD4 | MAX dimerization protein 4 |
| MZF1 | myeloid zinc finger 1 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NOP14-AS1 | NOP14 antisense RNA 1 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| NRP1 | neuropilin 1 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCNX | pecanex homolog (Drosophila) |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PGAP3 | post-GPI attachment to proteins 3 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PLK4 | polo-like kinase 4 |
| PMS2P2 | postmeiotic segregation increased 2 pseudogene 2 |
| POLL | polymerase (DNA directed), lambda |
| PPFIA3 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRLR | prolactin receptor |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RAB36 | RAB36, member RAS oncogene family |
| RAD51B | RAD51 paralog B |
| RALGDS | ral guanine nucleotide dissociation stimulator |
| REPS2 | RALBP1 associated Eps domain containing 2 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SESN1 | sestrin 1 |
| SFTPB | surfactant protein B |
| SIRT5 | sirtuin 5 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 |
| SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 |
| SSPN | sarcospan |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STK11 | serine/threonine kinase 11 |
| TDRD3 | tudor domain containing 3 |
| TMC6 | transmembrane channel-like 6 |
| TMEM8B | transmembrane protein 8B |
| TOM1 | target of myb1 (chicken) |
| TRAPPC13 | trafficking protein particle complex 13 |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| TREX1 | three prime repair exonuclease 1 |
| TRIM21 | tripartite motif containing 21 |
| TTC28 | tetratricopeptide repeat domain 28 |
| TXNIP | thioredoxin interacting protein |
| USP34 | ubiquitin specific peptidase 34 |
| WDR19 | WD repeat domain 19 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF10 | zinc finger protein 10 |
| ZNF350 | zinc finger protein 350 |
| ZNF747 | zinc finger protein 747 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| ACTN4 | actinin, alpha 4 |
| ADM | adrenomedullin |
| AEN | apoptosis enhancing nuclease |
| AFAP1 | actin filament associated protein 1 |
| ASB6 | ankyrin repeat and SOCS box containing 6 |
| BCL7B | B-cell CLL/lymphoma 7B |
| C12ORF43 | chromosome 12 open reading frame 43 |
| C1ORF109 | chromosome 1 open reading frame 109 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CADPS2 | Ca++-dependent secretion activator 2 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CCDC86 | coiled-coil domain containing 86 |
| CDR2 | cerebellar degeneration-related protein 2, 62kDa |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHMP7 | charged multivesicular body protein 7 |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CRY1 | cryptochrome circadian clock 1 |
| CRYBG3 | beta-gamma crystallin domain containing 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 |
| DEAF1 | DEAF1 transcription factor |
| DENND1B | DENN/MADD domain containing 1B |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| EAF2 | ELL associated factor 2 |
| EFHD2 | EF-hand domain family, member D2 |
| EPHA2 | EPH receptor A2 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FHOD1 | formin homology 2 domain containing 1 |
| FOSL1 | FOS-like antigen 1 |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| GALK1 | galactokinase 1 |
| GDAP2 | ganglioside induced differentiation associated protein 2 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GPATCH3 | G patch domain containing 3 |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HMHA1 | histocompatibility (minor) HA-1 |
| IFRD1 | interferon-related developmental regulator 1 |
| IL4R | interleukin 4 receptor |
| IP6K1 | inositol hexakisphosphate kinase 1 |
| KIAA0020 | KIAA0020 |
| KLHL2 | kelch-like family member 2 |
| LRIF1 | ligand dependent nuclear receptor interacting factor 1 |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) |
| MAP1S | microtubule-associated protein 1S |
| MDM4 | MDM4, p53 regulator |
| METTL1 | methyltransferase like 1 |
| MIR22HG | MIR22 host gene |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MT1HL1 | metallothionein 1H-like 1 |
| MUM1 | melanoma associated antigen (mutated) 1 |
| PANK4 | pantothenate kinase 4 |
| PARG | poly (ADP-ribose) glycohydrolase |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PER3 | period circadian clock 3 |
| PGP | phosphoglycolate phosphatase |
| PGPEP1 | pyroglutamyl-peptidase I |
| PLA2G10 | phospholipase A2, group X |
| PPM1E | protein phosphatase, Mg2+/Mn2+ dependent, 1E |
| RAI14 | retinoic acid induced 14 |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RNF25 | ring finger protein 25 |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SH2D4A | SH2 domain containing 4A |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC25A32 | solute carrier family 25 (mitochondrial folate carrier), member 32 |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 |
| SPIDR | scaffolding protein involved in DNA repair |
| STXBP1 | syntaxin binding protein 1 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| SURF2 | surfeit 2 |
| SYBU | syntabulin (syntaxin-interacting) |
| SYT17 | synaptotagmin XVII |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
| TESK1 | testis-specific kinase 1 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM120B | transmembrane protein 120B |
| TMEM2 | transmembrane protein 2 |
| TMEM38B | transmembrane protein 38B |
| TRMT13 | tRNA methyltransferase 13 homolog (S. cerevisiae) |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TTC33 | tetratricopeptide repeat domain 33 |
| UNC119 | unc-119 homolog (C. elegans) |
| USP36 | ubiquitin specific peptidase 36 |
| UTP20 | UTP20, small subunit (SSU) processome component, homolog (yeast) |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZNF365 | zinc finger protein 365 |
| ZNF623 | zinc finger protein 623 |
| ZNF787 | zinc finger protein 787 |
