| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the sirolimus-1022 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 |
| ABCD4 | ATP-binding cassette, sub-family D (ALD), member 4 |
| ADAP1 | ArfGAP with dual PH domains 1 |
| ADCK3 | aarF domain containing kinase 3 |
| AMT | aminomethyltransferase |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 |
| APOLD1 | apolipoprotein L domain containing 1 |
| B3GNTL1 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BLNK | B-cell linker |
| C10ORF95 | chromosome 10 open reading frame 95 |
| CA4 | carbonic anhydrase IV |
| CAPN9 | calpain 9 |
| CBX7 | chromobox homolog 7 |
| CCDC132 | coiled-coil domain containing 132 |
| CCDC28A | coiled-coil domain containing 28A |
| CCDC57 | coiled-coil domain containing 57 |
| CCNG2 | cyclin G2 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CCPG1 | cell cycle progression 1 |
| CDC25C | cell division cycle 25C |
| CDC42EP2 | CDC42 effector protein (Rho GTPase binding) 2 |
| CDK19 | cyclin-dependent kinase 19 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 |
| DMXL2 | Dmx-like 2 |
| DVL2 | dishevelled segment polarity protein 2 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| ERCC6 | excision repair cross-complementation group 6 |
| ERP44 | endoplasmic reticulum protein 44 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FAM114A2 | family with sequence similarity 114, member A2 |
| FLJ42627 | uncharacterized LOC645644 |
| GPER1 | G protein-coupled estrogen receptor 1 |
| GSDMB | gasdermin B |
| HBP1 | HMG-box transcription factor 1 |
| HDAC7 | histone deacetylase 7 |
| HEG1 | heart development protein with EGF-like domains 1 |
| HFE | hemochromatosis |
| HLA-DRB6 | major histocompatibility complex, class II, DR beta 6 (pseudogene) |
| HLA-F | major histocompatibility complex, class I, F |
| HSPA1L | heat shock 70kDa protein 1-like |
| IRS2 | insulin receptor substrate 2 |
| KAZALD1 | Kazal-type serine peptidase inhibitor domain 1 |
| KCNAB2 | potassium channel, voltage gated subfamily A regulatory beta subunit 2 |
| KDSR | 3-ketodihydrosphingosine reductase |
| KIAA0754 | KIAA0754 |
| KLHL24 | kelch-like family member 24 |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| LAMC2 | laminin, gamma 2 |
| LIMCH1 | LIM and calponin homology domains 1 |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MID1 | midline 1 |
| MSRB2 | methionine sulfoxide reductase B2 |
| MTRF1L | mitochondrial translational release factor 1-like |
| MYOF | myoferlin |
| MZF1 | myeloid zinc finger 1 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NF1 | neurofibromin 1 |
| NFX1 | nuclear transcription factor, X-box binding 1 |
| NKX3-2 | NK3 homeobox 2 |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PMS2P2 | postmeiotic segregation increased 2 pseudogene 2 |
| PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PRSS16 | protease, serine, 16 (thymus) |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RALGDS | ral guanine nucleotide dissociation stimulator |
| RGS10 | regulator of G-protein signaling 10 |
| RIN2 | Ras and Rab interactor 2 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| RTN2 | reticulon 2 |
| SCAPER | S-phase cyclin A-associated protein in the ER |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SIDT2 | SID1 transmembrane family, member 2 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SNX29 | sorting nexin 29 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| TGFB2 | transforming growth factor, beta 2 |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TRIO | trio Rho guanine nucleotide exchange factor |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 |
| TXNIP | thioredoxin interacting protein |
| ZBTB44 | zinc finger and BTB domain containing 44 |
| ZNF33B | zinc finger protein 33B |
| ZNF34 | zinc finger protein 34 |
| ZNF446 | zinc finger protein 446 |
| ZNF589 | zinc finger protein 589 |
| ZNF606 | zinc finger protein 606 |
| ZNF747 | zinc finger protein 747 |
| ZNF821 | zinc finger protein 821 |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| AFAP1 | actin filament associated protein 1 |
| AHCTF1 | AT hook containing transcription factor 1 |
| ANKEF1 | ankyrin repeat and EF-hand domain containing 1 |
| ASCC2 | activating signal cointegrator 1 complex subunit 2 |
| ATAD3A | ATPase family, AAA domain containing 3A |
| BCORL1 | BCL6 corepressor-like 1 |
| BMP4 | bone morphogenetic protein 4 |
| BTBD2 | BTB (POZ) domain containing 2 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CCDC86 | coiled-coil domain containing 86 |
| CCDC88C | coiled-coil domain containing 88C |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CEP72 | centrosomal protein 72kDa |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHUK | conserved helix-loop-helix ubiquitous kinase |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CLSPN | claspin |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CPTP | ceramide-1-phosphate transfer protein |
| CRY2 | cryptochrome circadian clock 2 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DIXDC1 | DIX domain containing 1 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| EAF2 | ELL associated factor 2 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| EXOSC9 | exosome component 9 |
| FAM50B | family with sequence similarity 50, member B |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FKBP5 | FK506 binding protein 5 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| FOSL1 | FOS-like antigen 1 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GPRC5C | G protein-coupled receptor, class C, group 5, member C |
| GRTP1 | growth hormone regulated TBC protein 1 |
| GUF1 | GUF1 GTPase homolog (S. cerevisiae) |
| HCFC2 | host cell factor C2 |
| HIST1H2BJ | histone cluster 1, H2bj |
| HOMER1 | homer scaffolding protein 1 |
| HYAL2 | hyaluronoglucosaminidase 2 |
| IFRD1 | interferon-related developmental regulator 1 |
| IP6K1 | inositol hexakisphosphate kinase 1 |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| ITPKC | inositol-trisphosphate 3-kinase C |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KRT15 | keratin 15, type I |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LINS | lines homolog (Drosophila) |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
| MAP1S | microtubule-associated protein 1S |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MIR22HG | MIR22 host gene |
| NOP2 | NOP2 nucleolar protein |
| ODF2 | outer dense fiber of sperm tails 2 |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 |
| PPAN | peter pan homolog (Drosophila) |
| RARS | arginyl-tRNA synthetase |
| RECQL4 | RecQ protein-like 4 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RGS19 | regulator of G-protein signaling 19 |
| RNF121 | ring finger protein 121 |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SCAI | suppressor of cancer cell invasion |
| SDCCAG3 | serologically defined colon cancer antigen 3 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SH2B2 | SH2B adaptor protein 2 |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| SPATA2L | spermatogenesis associated 2-like |
| SPIDR | scaffolding protein involved in DNA repair |
| SPRYD7 | SPRY domain containing 7 |
| STRN | striatin, calmodulin binding protein |
| STX5 | syntaxin 5 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
| TARS | threonyl-tRNA synthetase |
| THAP4 | THAP domain containing 4 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM62 | transmembrane protein 62 |
| UTP20 | UTP20, small subunit (SSU) processome component, homolog (yeast) |
| WDR4 | WD repeat domain 4 |
| WDR43 | WD repeat domain 43 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZBTB3 | zinc finger and BTB domain containing 3 |
| ZNF41 | zinc finger protein 41 |
| ZNF770 | zinc finger protein 770 |
