| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the sirolimus-1045 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ABHD4 | abhydrolase domain containing 4 |
| ADCK3 | aarF domain containing kinase 3 |
| AGGF1 | angiogenic factor with G patch and FHA domains 1 |
| AHNAK | AHNAK nucleoprotein |
| ALPK1 | alpha-kinase 1 |
| ANKRD12 | ankyrin repeat domain 12 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ARRB1 | arrestin, beta 1 |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 |
| BCL6 | B-cell CLL/lymphoma 6 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like |
| C19ORF54 | chromosome 19 open reading frame 54 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
| CARD8 | caspase recruitment domain family, member 8 |
| CBX7 | chromobox homolog 7 |
| CCDC28A | coiled-coil domain containing 28A |
| CCNG2 | cyclin G2 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CTBS | chitobiase, di-N-acetyl- |
| CUEDC1 | CUE domain containing 1 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 |
| DET1 | de-etiolated homolog 1 (Arabidopsis) |
| DIAPH2 | diaphanous-related formin 2 |
| DNAAF1 | dynein, axonemal, assembly factor 1 |
| DSPP | dentin sialophosphoprotein |
| ETAA1 | Ewing tumor-associated antigen 1 |
| EZH1 | enhancer of zeste 1 polycomb repressive complex 2 subunit |
| FAM174B | family with sequence similarity 174, member B |
| FAM53B | family with sequence similarity 53, member B |
| FOXN3 | forkhead box N3 |
| GART | phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase |
| GAS8 | growth arrest-specific 8 |
| GOLGA1 | golgin A1 |
| GPR87 | G protein-coupled receptor 87 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A |
| GSN | gelsolin |
| GSTM1 | glutathione S-transferase mu 1 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HBP1 | HMG-box transcription factor 1 |
| HDAC6 | histone deacetylase 6 |
| HDGFRP3 | hepatoma-derived growth factor, related protein 3 |
| HIST1H2AE | histone cluster 1, H2ae |
| HLA-G | major histocompatibility complex, class I, G |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KIAA0195 | KIAA0195 |
| KIAA0430 | KIAA0430 |
| KLHL24 | kelch-like family member 24 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LUZP1 | leucine zipper protein 1 |
| MAGEH1 | melanoma antigen family H1 |
| MCOLN3 | mucolipin 3 |
| MED23 | mediator complex subunit 23 |
| MR1 | major histocompatibility complex, class I-related |
| MT1G | metallothionein 1G |
| MXD3 | MAX dimerization protein 3 |
| NBR1 | neighbor of BRCA1 gene 1 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| PCYOX1L | prenylcysteine oxidase 1 like |
| PEX10 | peroxisomal biogenesis factor 10 |
| PFDN6 | prefoldin subunit 6 |
| PIGV | phosphatidylinositol glycan anchor biosynthesis, class V |
| PINK1 | PTEN induced putative kinase 1 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PLXND1 | plexin D1 |
| PRKACA | protein kinase, cAMP-dependent, catalytic, alpha |
| PSEN2 | presenilin 2 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 |
| SASH1 | SAM and SH3 domain containing 1 |
| SFT2D2 | SFT2 domain containing 2 |
| SIDT1 | SID1 transmembrane family, member 1 |
| SIGMAR1 | sigma non-opioid intracellular receptor 1 |
| SIK1 | salt-inducible kinase 1 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLC35E2 | solute carrier family 35, member E2 |
| SMAD3 | SMAD family member 3 |
| SP100 | SP100 nuclear antigen |
| STC1 | stanniocalcin 1 |
| SUGP1 | SURP and G patch domain containing 1 |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| SUOX | sulfite oxidase |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| SYT17 | synaptotagmin XVII |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TPCN1 | two pore segment channel 1 |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TUBA3C | tubulin, alpha 3c |
| TXNIP | thioredoxin interacting protein |
| YLPM1 | YLP motif containing 1 |
| ZBTB25 | zinc finger and BTB domain containing 25 |
| ZSCAN9 | zinc finger and SCAN domain containing 9 |
| Symbol | Name |
|---|---|
| ABCC6 | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
| ADGRL2 | adhesion G protein-coupled receptor L2 |
| AHCTF1 | AT hook containing transcription factor 1 |
| AKIRIN1 | akirin 1 |
| AMPD2 | adenosine monophosphate deaminase 2 |
| ANAPC10 | anaphase promoting complex subunit 10 |
| ANKRD11 | ankyrin repeat domain 11 |
| AP1AR | adaptor-related protein complex 1 associated regulatory protein |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| ARMC7 | armadillo repeat containing 7 |
| ASCC2 | activating signal cointegrator 1 complex subunit 2 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| BRPF1 | bromodomain and PHD finger containing, 1 |
| BYSL | bystin-like |
| C1ORF109 | chromosome 1 open reading frame 109 |
| C9ORF91 | chromosome 9 open reading frame 91 |
| CAPN1 | calpain 1, (mu/I) large subunit |
| CCDC15 | coiled-coil domain containing 15 |
| CCDC59 | coiled-coil domain containing 59 |
| CCDC86 | coiled-coil domain containing 86 |
| CCNT1 | cyclin T1 |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma |
| CENPB | centromere protein B, 80kDa |
| CHD1 | chromodomain helicase DNA binding protein 1 |
| COA7 | cytochrome c oxidase assembly factor 7 (putative) |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DPH2 | DPH2 homolog (S. cerevisiae) |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FNDC3B | fibronectin type III domain containing 3B |
| GALE | UDP-galactose-4-epimerase |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GNL2 | guanine nucleotide binding protein-like 2 (nucleolar) |
| GPHN | gephyrin |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa |
| GTF2I | general transcription factor IIi |
| HCFC2 | host cell factor C2 |
| HDHD3 | haloacid dehalogenase-like hydrolase domain containing 3 |
| HYAL2 | hyaluronoglucosaminidase 2 |
| IFRD1 | interferon-related developmental regulator 1 |
| IMPA1 | inositol(myo)-1(or 4)-monophosphatase 1 |
| ING3 | inhibitor of growth family, member 3 |
| KIAA0020 | KIAA0020 |
| KIN | Kin17 DNA and RNA binding protein |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) |
| MANSC1 | MANSC domain containing 1 |
| METTL16 | methyltransferase like 16 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MIR22HG | MIR22 host gene |
| MIS12 | MIS12 kinetochore complex component |
| MIS18BP1 | MIS18 binding protein 1 |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MSL1 | male-specific lethal 1 homolog (Drosophila) |
| MSRA | methionine sulfoxide reductase A |
| MTERF1 | mitochondrial transcription termination factor 1 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit |
| NABP2 | nucleic acid binding protein 2 |
| NDUFAF4 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 |
| NECAP2 | NECAP endocytosis associated 2 |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein |
| NOP2 | NOP2 nucleolar protein |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NRBF2 | nuclear receptor binding factor 2 |
| NUPL1 | nucleoporin like 1 |
| NXN | nucleoredoxin |
| PCYOX1 | prenylcysteine oxidase 1 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 |
| RFX7 | regulatory factor X, 7 |
| RNF138 | ring finger protein 138, E3 ubiquitin protein ligase |
| RNF25 | ring finger protein 25 |
| RRP1 | ribosomal RNA processing 1 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SH3GL1 | SH3-domain GRB2-like 1 |
| SIRT7 | sirtuin 7 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SPIN1 | spindlin 1 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) |
| THAP4 | THAP domain containing 4 |
| TMEM8A | transmembrane protein 8A |
| UBN1 | ubinuclein 1 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| UTP20 | UTP20, small subunit (SSU) processome component, homolog (yeast) |
| UTP3 | UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) |
| WDR18 | WD repeat domain 18 |
| WDR43 | WD repeat domain 43 |
| WDR44 | WD repeat domain 44 |
| ZC2HC1A | zinc finger, C2HC-type containing 1A |
| ZNF124 | zinc finger protein 124 |
| ZNF160 | zinc finger protein 160 |
| ZNF195 | zinc finger protein 195 |
| ZNF593 | zinc finger protein 593 |
