| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the sirolimus-1059 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
| ABHD2 | abhydrolase domain containing 2 |
| ADCK3 | aarF domain containing kinase 3 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ALPK1 | alpha-kinase 1 |
| AMDHD2 | amidohydrolase domain containing 2 |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 |
| APOD | apolipoprotein D |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) |
| ATRN | attractin |
| AZI2 | 5-azacytidine induced 2 |
| BCKDHA | branched chain keto acid dehydrogenase E1, alpha polypeptide |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like |
| C11ORF71 | chromosome 11 open reading frame 71 |
| CBLB | Cbl proto-oncogene B, E3 ubiquitin protein ligase |
| CBX7 | chromobox homolog 7 |
| CCDC170 | coiled-coil domain containing 170 |
| CCNG2 | cyclin G2 |
| CIRBP | cold inducible RNA binding protein |
| CLN3 | ceroid-lipofuscinosis, neuronal 3 |
| COL9A2 | collagen, type IX, alpha 2 |
| CYP20A1 | cytochrome P450, family 20, subfamily A, polypeptide 1 |
| DET1 | de-etiolated homolog 1 (Arabidopsis) |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| ELF4 | E74-like factor 4 (ets domain transcription factor) |
| ERCC1 | excision repair cross-complementation group 1 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| ETHE1 | ethylmalonic encephalopathy 1 |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FGFR1OP | FGFR1 oncogene partner |
| FUT4 | fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) |
| GM2A | GM2 ganglioside activator |
| GOLGA4 | golgin A4 |
| HDAC6 | histone deacetylase 6 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HLA-G | major histocompatibility complex, class I, G |
| HOXC11 | homeobox C11 |
| HS1BP3 | HCLS1 binding protein 3 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa |
| IL15RA | interleukin 15 receptor, alpha |
| ILK | integrin-linked kinase |
| JRK | Jrk homolog (mouse) |
| KCNJ3 | potassium channel, inwardly rectifying subfamily J, member 3 |
| KIFAP3 | kinesin-associated protein 3 |
| KLHL24 | kelch-like family member 24 |
| KRBOX4 | KRAB box domain containing 4 |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LY6G5C | lymphocyte antigen 6 complex, locus G5C |
| METTL5 | methyltransferase like 5 |
| MT1F | metallothionein 1F |
| MT1G | metallothionein 1G |
| MT1H | metallothionein 1H |
| MXD4 | MAX dimerization protein 4 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NBR1 | neighbor of BRCA1 gene 1 |
| NCKAP1 | NCK-associated protein 1 |
| NDST2 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| OAZ3 | ornithine decarboxylase antizyme 3 |
| OSBPL2 | oxysterol binding protein-like 2 |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PCYOX1L | prenylcysteine oxidase 1 like |
| PIGV | phosphatidylinositol glycan anchor biosynthesis, class V |
| POFUT1 | protein O-fucosyltransferase 1 |
| POT1 | protection of telomeres 1 |
| PPM1A | protein phosphatase, Mg2+/Mn2+ dependent, 1A |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma |
| PPP2R5D | protein phosphatase 2, regulatory subunit B', delta |
| PRLR | prolactin receptor |
| PTMA | prothymosin, alpha |
| PTTG3P | pituitary tumor-transforming 3, pseudogene |
| REPS2 | RALBP1 associated Eps domain containing 2 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 |
| RXRB | retinoid X receptor, beta |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SPANXC | SPANX family, member C |
| TADA2A | transcriptional adaptor 2A |
| TMEM161A | transmembrane protein 161A |
| TMPRSS4 | transmembrane protease, serine 4 |
| TNK1 | tyrosine kinase, non-receptor, 1 |
| TRIM33 | tripartite motif containing 33 |
| TXNIP | thioredoxin interacting protein |
| UBB | ubiquitin B |
| URGCP | upregulator of cell proliferation |
| WDR61 | WD repeat domain 61 |
| ZMYM2 | zinc finger, MYM-type 2 |
| ZNF226 | zinc finger protein 226 |
| ZNF24 | zinc finger protein 24 |
| ZNF33B | zinc finger protein 33B |
| ZNF428 | zinc finger protein 428 |
| ZNF510 | zinc finger protein 510 |
| ZNF571 | zinc finger protein 571 |
| ZNF85 | zinc finger protein 85 |
| Symbol | Name |
|---|---|
| ABT1 | activator of basal transcription 1 |
| ADSS | adenylosuccinate synthase |
| AHCTF1 | AT hook containing transcription factor 1 |
| ANKEF1 | ankyrin repeat and EF-hand domain containing 1 |
| APPL1 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 |
| ARHGAP11A | Rho GTPase activating protein 11A |
| ARL4A | ADP-ribosylation factor-like 4A |
| ASB6 | ankyrin repeat and SOCS box containing 6 |
| ASCC2 | activating signal cointegrator 1 complex subunit 2 |
| C4ORF19 | chromosome 4 open reading frame 19 |
| CCDC86 | coiled-coil domain containing 86 |
| CCNE1 | cyclin E1 |
| CDC45 | cell division cycle 45 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta |
| CEP72 | centrosomal protein 72kDa |
| CHMP7 | charged multivesicular body protein 7 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CRY1 | cryptochrome circadian clock 1 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DPF2 | D4, zinc and double PHD fingers family 2 |
| DUSP14 | dual specificity phosphatase 14 |
| DVL1 | dishevelled segment polarity protein 1 |
| EDC3 | enhancer of mRNA decapping 3 |
| EDC4 | enhancer of mRNA decapping 4 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 |
| ENTPD6 | ectonucleoside triphosphate diphosphohydrolase 6 (putative) |
| FHOD1 | formin homology 2 domain containing 1 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 |
| FOXC1 | forkhead box C1 |
| GATAD2A | GATA zinc finger domain containing 2A |
| GCA | grancalcin, EF-hand calcium binding protein |
| GCC1 | GRIP and coiled-coil domain containing 1 |
| GHR | growth hormone receptor |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa |
| GTPBP6 | GTP binding protein 6 (putative) |
| HEATR3 | HEAT repeat containing 3 |
| IER3 | immediate early response 3 |
| IFRD1 | interferon-related developmental regulator 1 |
| INSIG2 | insulin induced gene 2 |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| KATNBL1 | katanin p80 subunit B-like 1 |
| KLHDC10 | kelch domain containing 10 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 |
| MDN1 | MDN1, midasin homolog (yeast) |
| MIR22HG | MIR22 host gene |
| MKKS | McKusick-Kaufman syndrome |
| MRGBP | MRG/MORF4L binding protein |
| MTHFS | 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) |
| NABP2 | nucleic acid binding protein 2 |
| NCAPD3 | non-SMC condensin II complex, subunit D3 |
| NOP2 | NOP2 nucleolar protein |
| NXN | nucleoredoxin |
| OSBPL11 | oxysterol binding protein-like 11 |
| PAM16 | presequence translocase-associated motor 16 homolog (S. cerevisiae) |
| PCNXL4 | pecanex-like 4 (Drosophila) |
| PDCD11 | programmed cell death 11 |
| PDZRN3 | PDZ domain containing ring finger 3 |
| PFDN1 | prefoldin subunit 1 |
| PHACTR4 | phosphatase and actin regulator 4 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PKN1 | protein kinase N1 |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 |
| PRMT7 | protein arginine methyltransferase 7 |
| PRR7 | proline rich 7 (synaptic) |
| PTPN9 | protein tyrosine phosphatase, non-receptor type 9 |
| RAI14 | retinoic acid induced 14 |
| REV1 | REV1, polymerase (DNA directed) |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RPL23AP7 | ribosomal protein L23a pseudogene 7 |
| S100A6 | S100 calcium binding protein A6 |
| SCAMP3 | secretory carrier membrane protein 3 |
| SCML1 | sex comb on midleg-like 1 (Drosophila) |
| SERINC5 | serine incorporator 5 |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain |
| SLC25A10 | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 |
| SLMO2 | slowmo homolog 2 (Drosophila) |
| SMYD5 | SMYD family member 5 |
| SRRD | SRR1 domain containing |
| SSFA2 | sperm specific antigen 2 |
| STEAP3 | STEAP family member 3, metalloreductase |
| STRN4 | striatin, calmodulin binding protein 4 |
| SURF2 | surfeit 2 |
| TAF2 | TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa |
| THOP1 | thimet oligopeptidase 1 |
| TMEM109 | transmembrane protein 109 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) |
| UNKL | unkempt family zinc finger-like |
| UTP20 | UTP20, small subunit (SSU) processome component, homolog (yeast) |
| WDR3 | WD repeat domain 3 |
| YAF2 | YY1 associated factor 2 |
| ZFP36 | ZFP36 ring finger protein |
