| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the sirolimus-1080 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD4 | abhydrolase domain containing 4 |
| ABLIM3 | actin binding LIM protein family, member 3 |
| ACVR2B | activin A receptor, type IIB |
| AK2 | adenylate kinase 2 |
| AMOTL2 | angiomotin like 2 |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 |
| APOD | apolipoprotein D |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARIH2 | ariadne RBR E3 ubiquitin protein ligase 2 |
| ARMC6 | armadillo repeat containing 6 |
| ARRB1 | arrestin, beta 1 |
| ATP13A2 | ATPase type 13A2 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like |
| C22ORF46 | chromosome 22 open reading frame 46 |
| C2CD2L | C2CD2-like |
| CACTIN | cactin, spliceosome C complex subunit |
| CALHM2 | calcium homeostasis modulator 2 |
| CBX7 | chromobox homolog 7 |
| CEP152 | centrosomal protein 152kDa |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CSNK1E | casein kinase 1, epsilon |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| CTNS | cystinosin, lysosomal cystine transporter |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DNAL4 | dynein, axonemal, light chain 4 |
| FAM174B | family with sequence similarity 174, member B |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| FER1L4 | fer-1-like family member 4, pseudogene (functional) |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| HBP1 | HMG-box transcription factor 1 |
| HOXC11 | homeobox C11 |
| HPS4 | Hermansky-Pudlak syndrome 4 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| IL4R | interleukin 4 receptor |
| INPP5K | inositol polyphosphate-5-phosphatase K |
| IRF9 | interferon regulatory factor 9 |
| ITGB5 | integrin, beta 5 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KLHL24 | kelch-like family member 24 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 |
| LPIN2 | lipin 2 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| METTL5 | methyltransferase like 5 |
| MFAP3L | microfibrillar-associated protein 3-like |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MOSPD3 | motile sperm domain containing 3 |
| MR1 | major histocompatibility complex, class I-related |
| MSH3 | mutS homolog 3 |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog |
| NAGLU | N-acetylglucosaminidase, alpha |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NEK1 | NIMA-related kinase 1 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| PCYOX1L | prenylcysteine oxidase 1 like |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PHF8 | PHD finger protein 8 |
| PHKB | phosphorylase kinase, beta |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PLCG1 | phospholipase C, gamma 1 |
| PLCH1 | phospholipase C, eta 1 |
| POFUT1 | protein O-fucosyltransferase 1 |
| PPOX | protoporphyrinogen oxidase |
| PRMT2IP | PRMT2 interacting protein |
| PSEN2 | presenilin 2 |
| RGS10 | regulator of G-protein signaling 10 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SGSM2 | small G protein signaling modulator 2 |
| SIDT1 | SID1 transmembrane family, member 1 |
| SIRT3 | sirtuin 3 |
| SIVA1 | SIVA1, apoptosis-inducing factor |
| SLC11A2 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMCO3 | transmembrane and coiled-coil domains 3 |
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TNRC6B | trinucleotide repeat containing 6B |
| TOP3A | topoisomerase (DNA) III alpha |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TXNIP | thioredoxin interacting protein |
| TXNL4A | thioredoxin-like 4A |
| TYMS | thymidylate synthetase |
| UBE2W | ubiquitin-conjugating enzyme E2W (putative) |
| UBXN6 | UBX domain protein 6 |
| VSIG10 | V-set and immunoglobulin domain containing 10 |
| YLPM1 | YLP motif containing 1 |
| YY1 | YY1 transcription factor |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF226 | zinc finger protein 226 |
| ZNF324 | zinc finger protein 324 |
| ZNF710 | zinc finger protein 710 |
| Symbol | Name |
|---|---|
| AARSD1 | alanyl-tRNA synthetase domain containing 1 |
| AHCTF1 | AT hook containing transcription factor 1 |
| ALKBH1 | alkB, alkylation repair homolog 1 (E. coli) |
| ARRB2 | arrestin, beta 2 |
| ATF4 | activating transcription factor 4 |
| AVPI1 | arginine vasopressin-induced 1 |
| BDH2 | 3-hydroxybutyrate dehydrogenase, type 2 |
| BMS1 | BMS1 ribosome biogenesis factor |
| BYSL | bystin-like |
| CCDC59 | coiled-coil domain containing 59 |
| CCND3 | cyclin D3 |
| CDC34 | cell division cycle 34 |
| CDC37L1 | cell division cycle 37-like 1 |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma |
| CTPS1 | CTP synthase 1 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DAAM1 | dishevelled associated activator of morphogenesis 1 |
| DDA1 | DET1 and DDB1 associated 1 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DENR | density-regulated protein |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| DNAJC7 | DnaJ (Hsp40) homolog, subfamily C, member 7 |
| DYNC1LI1 | dynein, cytoplasmic 1, light intermediate chain 1 |
| ECHDC1 | ethylmalonyl-CoA decarboxylase 1 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 |
| EFHC1 | EF-hand domain (C-terminal) containing 1 |
| EFNA4 | ephrin-A4 |
| EGR3 | early growth response 3 |
| EIF6 | eukaryotic translation initiation factor 6 |
| ERCC3 | excision repair cross-complementation group 3 |
| FAM188A | family with sequence similarity 188, member A |
| FBXL12 | F-box and leucine-rich repeat protein 12 |
| GHR | growth hormone receptor |
| GLA | galactosidase, alpha |
| GNL2 | guanine nucleotide binding protein-like 2 (nucleolar) |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa |
| GTF2I | general transcription factor IIi |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| IFRD1 | interferon-related developmental regulator 1 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| IMPA1 | inositol(myo)-1(or 4)-monophosphatase 1 |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| IRX5 | iroquois homeobox 5 |
| KIAA0020 | KIAA0020 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) |
| LIN37 | lin-37 DREAM MuvB core complex component |
| MAGEF1 | melanoma antigen family F1 |
| MCAT | malonyl CoA:ACP acyltransferase (mitochondrial) |
| MEIS3P1 | Meis homeobox 3 pseudogene 1 |
| METTL16 | methyltransferase like 16 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 |
| MRPL17 | mitochondrial ribosomal protein L17 |
| MRTO4 | mRNA turnover 4 homolog (S. cerevisiae) |
| NAA38 | N(alpha)-acetyltransferase 38, NatC auxiliary subunit |
| NABP2 | nucleic acid binding protein 2 |
| NDUFA7 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa |
| NDUFAF4 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 |
| NECAP2 | NECAP endocytosis associated 2 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein |
| NXN | nucleoredoxin |
| OCEL1 | occludin/ELL domain containing 1 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) |
| PDZRN3 | PDZ domain containing ring finger 3 |
| PGM1 | phosphoglucomutase 1 |
| PUS1 | pseudouridylate synthase 1 |
| RABEPK | Rab9 effector protein with kelch motifs |
| RAI14 | retinoic acid induced 14 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 |
| RARS | arginyl-tRNA synthetase |
| RPS21 | ribosomal protein S21 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SCYL2 | SCY1-like 2 (S. cerevisiae) |
| SERINC5 | serine incorporator 5 |
| SETD6 | SET domain containing 6 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SIRT7 | sirtuin 7 |
| SMNDC1 | survival motor neuron domain containing 1 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa |
| SRRD | SRR1 domain containing |
| STXBP2 | syntaxin binding protein 2 |
| SURF2 | surfeit 2 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
| TBP | TATA box binding protein |
| THAP4 | THAP domain containing 4 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) |
| TRNAU1AP | tRNA selenocysteine 1 associated protein 1 |
| TXLNG | taxilin gamma |
| UBE2S | ubiquitin-conjugating enzyme E2S |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| UTP20 | UTP20, small subunit (SSU) processome component, homolog (yeast) |
| UTP6 | UTP6, small subunit (SSU) processome component, homolog (yeast) |
| WDR44 | WD repeat domain 44 |
| WDR47 | WD repeat domain 47 |
| YRDC | yrdC N(6)-threonylcarbamoyltransferase domain containing |
| ZNF394 | zinc finger protein 394 |
