| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
198 genes differentially expressed following the sirolimus-1148 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACOX1 | acyl-CoA oxidase 1, palmitoyl |
| ACVR2A | activin A receptor, type IIA |
| ADA | adenosine deaminase |
| AEN | apoptosis enhancing nuclease |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 |
| AOAH | acyloxyacyl hydrolase (neutrophil) |
| AP2A2 | adaptor-related protein complex 2, alpha 2 subunit |
| AREG | amphiregulin |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BNC2 | basonuclin 2 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CAPRIN2 | caprin family member 2 |
| CCDC28A | coiled-coil domain containing 28A |
| CCDC92 | coiled-coil domain containing 92 |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) |
| CDC25C | cell division cycle 25C |
| CDK3 | cyclin-dependent kinase 3 |
| CHML | choroideremia-like (Rab escort protein 2) |
| CLCA1 | chloride channel accessory 1 |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CPTP | ceramide-1-phosphate transfer protein |
| CYLC1 | cylicin, basic protein of sperm head cytoskeleton 1 |
| DEPDC5 | DEP domain containing 5 |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| ELL | elongation factor RNA polymerase II |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
| FAM13A | family with sequence similarity 13, member A |
| FAM3A | family with sequence similarity 3, member A |
| FBLN1 | fibulin 1 |
| G0S2 | G0/G1 switch 2 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GK | glycerol kinase |
| GLIPR1 | GLI pathogenesis-related 1 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 |
| GNRH1 | gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) |
| GPRC5C | G protein-coupled receptor, class C, group 5, member C |
| GRIP2 | glutamate receptor interacting protein 2 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| IL24 | interleukin 24 |
| IL27RA | interleukin 27 receptor, alpha |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| ITGB5 | integrin, beta 5 |
| KYNU | kynureninase |
| LPAR1 | lysophosphatidic acid receptor 1 |
| LPAR4 | lysophosphatidic acid receptor 4 |
| LPPR2 | lipid phosphate phosphatase-related protein type 2 |
| LY6E | lymphocyte antigen 6 complex, locus E |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MILR1 | mast cell immunoglobulin-like receptor 1 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NBEAL2 | neurobeachin-like 2 |
| NDOR1 | NADPH dependent diflavin oxidoreductase 1 |
| NKTR | natural killer cell triggering receptor |
| NOTCH4 | notch 4 |
| NPDC1 | neural proliferation, differentiation and control, 1 |
| NPR2 | natriuretic peptide receptor 2 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| PCGF3 | polycomb group ring finger 3 |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PER2 | period circadian clock 2 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 |
| PRAMEF11 | PRAME family member 11 |
| PRKACA | protein kinase, cAMP-dependent, catalytic, alpha |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| REST | RE1-silencing transcription factor |
| RGS14 | regulator of G-protein signaling 14 |
| RGS5 | regulator of G-protein signaling 5 |
| RPS9 | ribosomal protein S9 |
| RUFY3 | RUN and FYVE domain containing 3 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC35A2 | solute carrier family 35 (UDP-galactose transporter), member A2 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SSX1 | synovial sarcoma, X breakpoint 1 |
| SSX3 | synovial sarcoma, X breakpoint 3 |
| STAT5A | signal transducer and activator of transcription 5A |
| STMN1 | stathmin 1 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| THBS1 | thrombospondin 1 |
| TLN1 | talin 1 |
| TMEM144 | transmembrane protein 144 |
| TRANK1 | tetratricopeptide repeat and ankyrin repeat containing 1 |
| USF2 | upstream transcription factor 2, c-fos interacting |
| WDFY3 | WD repeat and FYVE domain containing 3 |
| WFDC2 | WAP four-disulfide core domain 2 |
| XAB2 | XPA binding protein 2 |
| ZBTB25 | zinc finger and BTB domain containing 25 |
| ZNF235 | zinc finger protein 235 |
| ZNF442 | zinc finger protein 442 |
| ZNF695 | zinc finger protein 695 |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ACO1 | aconitase 1, soluble |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| ANXA3 | annexin A3 |
| ARFIP2 | ADP-ribosylation factor interacting protein 2 |
| BBS10 | Bardet-Biedl syndrome 10 |
| C12ORF43 | chromosome 12 open reading frame 43 |
| C14ORF159 | chromosome 14 open reading frame 159 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| CD52 | CD52 molecule |
| CDIP1 | cell death-inducing p53 target 1 |
| CEP70 | centrosomal protein 70kDa |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHMP1A | charged multivesicular body protein 1A |
| CHMP7 | charged multivesicular body protein 7 |
| CLSTN1 | calsyntenin 1 |
| CLTCL1 | clathrin, heavy chain-like 1 |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CTSG | cathepsin G |
| DDHD2 | DDHD domain containing 2 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DEF8 | differentially expressed in FDCP 8 homolog (mouse) |
| DENND4A | DENN/MADD domain containing 4A |
| ECSIT | ECSIT signalling integrator |
| EOGT | EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase |
| FAM114A2 | family with sequence similarity 114, member A2 |
| FAM188A | family with sequence similarity 188, member A |
| FKBPL | FK506 binding protein like |
| GCHFR | GTP cyclohydrolase I feedback regulator |
| GPR22 | G protein-coupled receptor 22 |
| GRAMD1B | GRAM domain containing 1B |
| GTF3C4 | general transcription factor IIIC, polypeptide 4, 90kDa |
| HRAS | Harvey rat sarcoma viral oncogene homolog |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IMP4 | IMP4, U3 small nucleolar ribonucleoprotein |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| JMJD4 | jumonji domain containing 4 |
| KBTBD4 | kelch repeat and BTB (POZ) domain containing 4 |
| KCNA3 | potassium channel, voltage gated shaker related subfamily A, member 3 |
| KIAA0556 | KIAA0556 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 |
| LRRK1 | leucine-rich repeat kinase 1 |
| MAGEB2 | melanoma antigen family B2 |
| NDUFAB1 | NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa |
| NMB | neuromedin B |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| OCEL1 | occludin/ELL domain containing 1 |
| OTUD3 | OTU deubiquitinase 3 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PELP1 | proline, glutamate and leucine rich protein 1 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 |
| PJA1 | praja ring finger 1, E3 ubiquitin protein ligase |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 |
| PNMA1 | paraneoplastic Ma antigen 1 |
| POLR2F | polymerase (RNA) II (DNA directed) polypeptide F |
| POLR3K | polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa |
| PPIP5K2 | diphosphoinositol pentakisphosphate kinase 2 |
| PPP2R1A | protein phosphatase 2, regulatory subunit A, alpha |
| PSAT1 | phosphoserine aminotransferase 1 |
| PTDSS2 | phosphatidylserine synthase 2 |
| PTOV1 | prostate tumor overexpressed 1 |
| PUS1 | pseudouridylate synthase 1 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RABL6 | RAB, member RAS oncogene family-like 6 |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RNF122 | ring finger protein 122 |
| RNF31 | ring finger protein 31 |
| RPS6KB2 | ribosomal protein S6 kinase, 70kDa, polypeptide 2 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| SCML1 | sex comb on midleg-like 1 (Drosophila) |
| SIPA1 | signal-induced proliferation-associated 1 |
| SLC2A9 | solute carrier family 2 (facilitated glucose transporter), member 9 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| STAG3 | stromal antigen 3 |
| STBD1 | starch binding domain 1 |
| TAF6 | TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa |
| TERT | telomerase reverse transcriptase |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| TRABD | TraB domain containing |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TRIM68 | tripartite motif containing 68 |
| TSR2 | TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) |
| TTC27 | tetratricopeptide repeat domain 27 |
| TTC4 | tetratricopeptide repeat domain 4 |
| TTPAL | tocopherol (alpha) transfer protein-like |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| WASF3 | WAS protein family, member 3 |
| WDR60 | WD repeat domain 60 |
| XKR8 | XK, Kell blood group complex subunit-related family, member 8 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF16 | zinc finger protein 16 |
| ZNF480 | zinc finger protein 480 |
| ZNF552 | zinc finger protein 552 |
| ZNF557 | zinc finger protein 557 |
| ZNF675 | zinc finger protein 675 |
