| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the sirolimus-1162 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACOX1 | acyl-CoA oxidase 1, palmitoyl |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| ALOXE3 | arachidonate lipoxygenase 3 |
| ALS2CL | ALS2 C-terminal like |
| AMDHD2 | amidohydrolase domain containing 2 |
| AQP9 | aquaporin 9 |
| ARHGAP25 | Rho GTPase activating protein 25 |
| ARL4C | ADP-ribosylation factor-like 4C |
| ATG3 | autophagy related 3 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| BMP1 | bone morphogenetic protein 1 |
| C19ORF54 | chromosome 19 open reading frame 54 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CC2D1A | coiled-coil and C2 domain containing 1A |
| CD24 | CD24 molecule |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| COMT | catechol-O-methyltransferase |
| CPED1 | cadherin-like and PC-esterase domain containing 1 |
| CSF2RA | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) |
| CTC1 | CTS telomere maintenance complex component 1 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 |
| DDAH2 | dimethylarginine dimethylaminohydrolase 2 |
| DICER1 | dicer 1, ribonuclease type III |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| ELL | elongation factor RNA polymerase II |
| FCER2 | Fc fragment of IgE, low affinity II, receptor for (CD23) |
| GLIPR1 | GLI pathogenesis-related 1 |
| GM2A | GM2 ganglioside activator |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 |
| GPD2 | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) |
| HEMK1 | HemK methyltransferase family member 1 |
| IFNA14 | interferon, alpha 14 |
| IL24 | interleukin 24 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| KIAA0753 | KIAA0753 |
| KLHL24 | kelch-like family member 24 |
| KYNU | kynureninase |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 |
| MAST2 | microtubule associated serine/threonine kinase 2 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MNMIP1 | manchette microtubule inner protein 1 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| NF2 | neurofibromin 2 (merlin) |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NPEPL1 | aminopeptidase-like 1 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PADI1 | peptidyl arginine deiminase, type I |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 |
| PDLIM5 | PDZ and LIM domain 5 |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLCG1 | phospholipase C, gamma 1 |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PPP2R4 | protein phosphatase 2A activator, regulatory subunit 4 |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha |
| PTBP3 | polypyrimidine tract binding protein 3 |
| RASGRF1 | Ras protein-specific guanine nucleotide-releasing factor 1 |
| RGS10 | regulator of G-protein signaling 10 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SIK1 | salt-inducible kinase 1 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SMARCD1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 |
| SNTA1 | syntrophin, alpha 1 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SP140 | SP140 nuclear body protein |
| SPAG8 | sperm associated antigen 8 |
| SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 |
| STAB2 | stabilin 2 |
| SULT1A2 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 |
| TBCD | tubulin folding cofactor D |
| TESK1 | testis-specific kinase 1 |
| TGFBR1 | transforming growth factor, beta receptor 1 |
| THBS1 | thrombospondin 1 |
| TLR4 | toll-like receptor 4 |
| TMEM231 | transmembrane protein 231 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 |
| TPM2 | tropomyosin 2 (beta) |
| TRAF1 | TNF receptor-associated factor 1 |
| TRAFD1 | TRAF-type zinc finger domain containing 1 |
| TWF1 | twinfilin actin binding protein 1 |
| UGGT1 | UDP-glucose glycoprotein glucosyltransferase 1 |
| WDR33 | WD repeat domain 33 |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| ZFHX2 | zinc finger homeobox 2 |
| ZNF202 | zinc finger protein 202 |
| ZNF32 | zinc finger protein 32 |
| ZNF354A | zinc finger protein 354A |
| ZSCAN16 | zinc finger and SCAN domain containing 16 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| AHCTF1 | AT hook containing transcription factor 1 |
| AMBRA1 | autophagy/beclin-1 regulator 1 |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| ARFIP2 | ADP-ribosylation factor interacting protein 2 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| C5ORF30 | chromosome 5 open reading frame 30 |
| CAPN15 | calpain 15 |
| CBLL1 | Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CDK5 | cyclin-dependent kinase 5 |
| CEBPE | CCAAT/enhancer binding protein (C/EBP), epsilon |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CORO7 | coronin 7 |
| CPSF7 | cleavage and polyadenylation specific factor 7, 59kDa |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 |
| EDC3 | enhancer of mRNA decapping 3 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EGLN2 | egl-9 family hypoxia-inducible factor 2 |
| EVL | Enah/Vasp-like |
| FAM172A | family with sequence similarity 172, member A |
| FAM50B | family with sequence similarity 50, member B |
| FGGY | FGGY carbohydrate kinase domain containing |
| FOXN2 | forkhead box N2 |
| GALNS | galactosamine (N-acetyl)-6-sulfatase |
| GCA | grancalcin, EF-hand calcium binding protein |
| GCC1 | GRIP and coiled-coil domain containing 1 |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa |
| HIPK1 | homeodomain interacting protein kinase 1 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IL4R | interleukin 4 receptor |
| INHBE | inhibin, beta E |
| INPP1 | inositol polyphosphate-1-phosphatase |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA0754 | KIAA0754 |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 |
| MAGEF1 | melanoma antigen family F1 |
| METTL8 | methyltransferase like 8 |
| MINPP1 | multiple inositol-polyphosphate phosphatase 1 |
| MON1B | MON1 secretory trafficking family member B |
| NAGPA | N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase |
| NHLRC2 | NHL repeat containing 2 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| OTUD3 | OTU deubiquitinase 3 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PBX3 | pre-B-cell leukemia homeobox 3 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 |
| PEG3 | paternally expressed 3 |
| PFAS | phosphoribosylformylglycinamidine synthase |
| PHACTR4 | phosphatase and actin regulator 4 |
| PNPLA6 | patatin-like phospholipase domain containing 6 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PRAF2 | PRA1 domain family, member 2 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| PTDSS2 | phosphatidylserine synthase 2 |
| PTER | phosphotriesterase related |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| RHOF | ras homolog family member F (in filopodia) |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RPAP2 | RNA polymerase II associated protein 2 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SND1-IT1 | SND1 intronic transcript 1 |
| SPATA2L | spermatogenesis associated 2-like |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
| SREK1IP1 | SREK1-interacting protein 1 |
| STIM1 | stromal interaction molecule 1 |
| STRN4 | striatin, calmodulin binding protein 4 |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| TERT | telomerase reverse transcriptase |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMEM156 | transmembrane protein 156 |
| TMEM164 | transmembrane protein 164 |
| TMEM254 | transmembrane protein 254 |
| TOLLIP | toll interacting protein |
| TPCN1 | two pore segment channel 1 |
| TRAPPC11 | trafficking protein particle complex 11 |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| TRMT12 | tRNA methyltransferase 12 homolog (S. cerevisiae) |
| TSPAN13 | tetraspanin 13 |
| TUBA3D | tubulin, alpha 3d |
| TWIST1 | twist family bHLH transcription factor 1 |
| TWISTNB | TWIST neighbor |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZDHHC18 | zinc finger, DHHC-type containing 18 |
| ZNF212 | zinc finger protein 212 |
| ZNF536 | zinc finger protein 536 |
| ZNF580 | zinc finger protein 580 |
