| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the sirolimus-1183 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACOX2 | acyl-CoA oxidase 2, branched chain |
| ACTA2 | actin, alpha 2, smooth muscle, aorta |
| ACVR2A | activin A receptor, type IIA |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ANKRD40 | ankyrin repeat domain 40 |
| AREG | amphiregulin |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| CD300C | CD300c molecule |
| CD59 | CD59 molecule, complement regulatory protein |
| CDC25C | cell division cycle 25C |
| CDK20 | cyclin-dependent kinase 20 |
| CES3 | carboxylesterase 3 |
| CPVL | carboxypeptidase, vitellogenic-like |
| CREM | cAMP responsive element modulator |
| CSF2RA | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) |
| CXCR3 | chemokine (C-X-C motif) receptor 3 |
| DBT | dihydrolipoamide branched chain transacylase E2 |
| DDAH2 | dimethylarginine dimethylaminohydrolase 2 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DTNA | dystrobrevin, alpha |
| DTX2P1-UPK3BP1-PMS2P11 | DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene |
| EGR3 | early growth response 3 |
| EIF1 | eukaryotic translation initiation factor 1 |
| ELL2 | elongation factor, RNA polymerase II, 2 |
| FAM105A | family with sequence similarity 105, member A |
| FCER2 | Fc fragment of IgE, low affinity II, receptor for (CD23) |
| FCMR | Fc fragment of IgM receptor |
| FPGS | folylpolyglutamate synthase |
| GK | glycerol kinase |
| GSDMD | gasdermin D |
| IDS | iduronate 2-sulfatase |
| IL1R1 | interleukin 1 receptor, type I |
| IL24 | interleukin 24 |
| KIAA0753 | KIAA0753 |
| KLF6 | Kruppel-like factor 6 |
| KLHL24 | kelch-like family member 24 |
| LAMP1 | lysosomal-associated membrane protein 1 |
| MAP2K3 | mitogen-activated protein kinase kinase 3 |
| MAX | MYC associated factor X |
| MCL1 | myeloid cell leukemia 1 |
| METTL7A | methyltransferase like 7A |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MIIP | migration and invasion inhibitory protein |
| MYBBP1A | MYB binding protein (P160) 1a |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| OCEL1 | occludin/ELL domain containing 1 |
| PARD3 | par-3 family cell polarity regulator |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCDH12 | protocadherin 12 |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PDE4D | phosphodiesterase 4D, cAMP-specific |
| PDLIM1 | PDZ and LIM domain 1 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PHACTR2 | phosphatase and actin regulator 2 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| PQLC2 | PQ loop repeat containing 2 |
| PRKACA | protein kinase, cAMP-dependent, catalytic, alpha |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 |
| PVR | poliovirus receptor |
| PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) |
| PYGB | phosphorylase, glycogen; brain |
| RAD52 | RAD52 homolog (S. cerevisiae) |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RHOB | ras homolog family member B |
| RIN3 | Ras and Rab interactor 3 |
| RTF1 | Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) |
| S1PR4 | sphingosine-1-phosphate receptor 4 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) |
| SHPK | sedoheptulokinase |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SIRT5 | sirtuin 5 |
| SLAMF7 | SLAM family member 7 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SNAPC5 | small nuclear RNA activating complex, polypeptide 5, 19kDa |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SPATA2 | spermatogenesis associated 2 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) |
| ST6GALNAC4 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 |
| STK16 | serine/threonine kinase 16 |
| STS | steroid sulfatase (microsomal), isozyme S |
| SULT1A2 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| THBS1 | thrombospondin 1 |
| TLR8 | toll-like receptor 8 |
| TULP3 | tubby like protein 3 |
| TWF1 | twinfilin actin binding protein 1 |
| VWA1 | von Willebrand factor A domain containing 1 |
| ZNF609 | zinc finger protein 609 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 |
| Symbol | Name |
|---|---|
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase |
| ADAM23 | ADAM metallopeptidase domain 23 |
| ANKRD28 | ankyrin repeat domain 28 |
| APOL6 | apolipoprotein L, 6 |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ARID5A | AT rich interactive domain 5A (MRF1-like) |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| C22ORF29 | chromosome 22 open reading frame 29 |
| CCDC186 | coiled-coil domain containing 186 |
| CCDC25 | coiled-coil domain containing 25 |
| CCNJ | cyclin J |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHMP1A | charged multivesicular body protein 1A |
| CKB | creatine kinase, brain |
| CLSPN | claspin |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CYSLTR1 | cysteinyl leukotriene receptor 1 |
| DDN | dendrin |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DNM1 | dynamin 1 |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| EDEM2 | ER degradation enhancer, mannosidase alpha-like 2 |
| FAM127A | family with sequence similarity 127, member A |
| FAM184A | family with sequence similarity 184, member A |
| FKBPL | FK506 binding protein like |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GTPBP6 | GTP binding protein 6 (putative) |
| HIRA | histone cell cycle regulator |
| HSPA4L | heat shock 70kDa protein 4-like |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LINS | lines homolog (Drosophila) |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 |
| METTL1 | methyltransferase like 1 |
| NAA16 | N(alpha)-acetyltransferase 16, NatA auxiliary subunit |
| NCS1 | neuronal calcium sensor 1 |
| NOL12 | nucleolar protein 12 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| PAK1IP1 | PAK1 interacting protein 1 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| POLH | polymerase (DNA directed), eta |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| PTCD1 | pentatricopeptide repeat domain 1 |
| PTOV1 | prostate tumor overexpressed 1 |
| PUS1 | pseudouridylate synthase 1 |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RNF31 | ring finger protein 31 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SAMD9 | sterile alpha motif domain containing 9 |
| SERINC5 | serine incorporator 5 |
| SIDT1 | SID1 transmembrane family, member 1 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SND1-IT1 | SND1 intronic transcript 1 |
| SPATA2L | spermatogenesis associated 2-like |
| SPATS2 | spermatogenesis associated, serine-rich 2 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| STC2 | stanniocalcin 2 |
| TERT | telomerase reverse transcriptase |
| TEX10 | testis expressed 10 |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| THBS4 | thrombospondin 4 |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TMEM134 | transmembrane protein 134 |
| TMEM57 | transmembrane protein 57 |
| TRMT61A | tRNA methyltransferase 61A |
| TUBA3C | tubulin, alpha 3c |
| TWIST1 | twist family bHLH transcription factor 1 |
| UNKL | unkempt family zinc finger-like |
| USB1 | U6 snRNA biogenesis 1 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VANGL1 | VANGL planar cell polarity protein 1 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZMAT3 | zinc finger, matrin-type 3 |
| ZNF408 | zinc finger protein 408 |
| ZNF552 | zinc finger protein 552 |
| ZNF747 | zinc finger protein 747 |
