| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the sirolimus-1207 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 |
| ADK | adenosine kinase |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ANXA10 | annexin A10 |
| ARL14 | ADP-ribosylation factor-like 14 |
| ARMC4 | armadillo repeat containing 4 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| BRWD1 | bromodomain and WD repeat domain containing 1 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C1RL | complement component 1, r subcomponent-like |
| C3AR1 | complement component 3a receptor 1 |
| CACNB3 | calcium channel, voltage-dependent, beta 3 subunit |
| CCDC186 | coiled-coil domain containing 186 |
| CCNG2 | cyclin G2 |
| CCNT2 | cyclin T2 |
| CCPG1 | cell cycle progression 1 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CHMP1B | charged multivesicular body protein 1B |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLN5 | ceroid-lipofuscinosis, neuronal 5 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial |
| CTNS | cystinosin, lysosomal cystine transporter |
| CYB561 | cytochrome b561 |
| DHODH | dihydroorotate dehydrogenase (quinone) |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DUSP1 | dual specificity phosphatase 1 |
| EGF | epidermal growth factor |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
| EIF3A | eukaryotic translation initiation factor 3, subunit A |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FH | fumarate hydratase |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GK | glycerol kinase |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HIST1H2BM | histone cluster 1, H2bm |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IGF1R | insulin-like growth factor 1 receptor |
| IL33 | interleukin 33 |
| ITFG2 | integrin alpha FG-GAP repeat containing 2 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 |
| KDM6A | lysine (K)-specific demethylase 6A |
| KLHL24 | kelch-like family member 24 |
| KRT20 | keratin 20, type I |
| LAG3 | lymphocyte-activation gene 3 |
| LCK | LCK proto-oncogene, Src family tyrosine kinase |
| LMF2 | lipase maturation factor 2 |
| LRRK1 | leucine-rich repeat kinase 1 |
| MAP3K7CL | MAP3K7 C-terminal like |
| MCOLN3 | mucolipin 3 |
| MT1H | metallothionein 1H |
| MT1X | metallothionein 1X |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| NNMT | nicotinamide N-methyltransferase |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| OPCML | opioid binding protein/cell adhesion molecule-like |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PILRA | paired immunoglobin-like type 2 receptor alpha |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PLSCR4 | phospholipid scramblase 4 |
| PPP1R7 | protein phosphatase 1, regulatory subunit 7 |
| PRKCI | protein kinase C, iota |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RB1CC1 | RB1-inducible coiled-coil 1 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPLP2 | ribosomal protein, large, P2 |
| RPS9 | ribosomal protein S9 |
| SENP3 | SUMO1/sentrin/SMT3 specific peptidase 3 |
| SEPP1 | selenoprotein P, plasma, 1 |
| SLC1A7 | solute carrier family 1 (glutamate transporter), member 7 |
| SMG5 | SMG5 nonsense mediated mRNA decay factor |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| SPN | sialophorin |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) |
| STX16 | syntaxin 16 |
| TDRKH | tudor and KH domain containing |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) |
| THRA | thyroid hormone receptor, alpha |
| TLE2 | transducin-like enhancer of split 2 |
| TLE4 | transducin-like enhancer of split 4 |
| TNFSF15 | tumor necrosis factor (ligand) superfamily, member 15 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| UBE3A | ubiquitin protein ligase E3A |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| VWA1 | von Willebrand factor A domain containing 1 |
| WDR45 | WD repeat domain 45 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZBTB7A | zinc finger and BTB domain containing 7A |
| ZFP30 | ZFP30 zinc finger protein |
| ZNF528 | zinc finger protein 528 |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| ABHD8 | abhydrolase domain containing 8 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| ADAMTS3 | ADAM metallopeptidase with thrombospondin type 1 motif, 3 |
| AEN | apoptosis enhancing nuclease |
| ANAPC2 | anaphase promoting complex subunit 2 |
| ARMC6 | armadillo repeat containing 6 |
| BCL9 | B-cell CLL/lymphoma 9 |
| BDNF | brain-derived neurotrophic factor |
| BYSL | bystin-like |
| CARD8 | caspase recruitment domain family, member 8 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase |
| CCDC86 | coiled-coil domain containing 86 |
| CENPT | centromere protein T |
| CHMP7 | charged multivesicular body protein 7 |
| CHPF | chondroitin polymerizing factor |
| CHST10 | carbohydrate sulfotransferase 10 |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| EAF2 | ELL associated factor 2 |
| EDC4 | enhancer of mRNA decapping 4 |
| EFNA3 | ephrin-A3 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FANCE | Fanconi anemia, complementation group E |
| FARSA | phenylalanyl-tRNA synthetase, alpha subunit |
| GBX2 | gastrulation brain homeobox 2 |
| GDAP2 | ganglioside induced differentiation associated protein 2 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
| HOXA2 | homeobox A2 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IL7R | interleukin 7 receptor |
| KIAA0513 | KIAA0513 |
| LNPEP | leucyl/cystinyl aminopeptidase |
| LONRF3 | LON peptidase N-terminal domain and ring finger 3 |
| MAGEA6 | melanoma antigen family A6 |
| MAGEF1 | melanoma antigen family F1 |
| MAK16 | MAK16 homolog (S. cerevisiae) |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MON1B | MON1 secretory trafficking family member B |
| MPHOSPH10 | M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) |
| MRTO4 | mRNA turnover 4 homolog (S. cerevisiae) |
| MTERF4 | mitochondrial transcription termination factor 4 |
| MTRF1 | mitochondrial translational release factor 1 |
| MXRA8 | matrix-remodelling associated 8 |
| NID2 | nidogen 2 (osteonidogen) |
| NOC4L | nucleolar complex associated 4 homolog (S. cerevisiae) |
| NRSN2 | neurensin 2 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| NXT1 | nuclear transport factor 2-like export factor 1 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| POLR1C | polymerase (RNA) I polypeptide C, 30kDa |
| POLR1E | polymerase (RNA) I polypeptide E, 53kDa |
| POMT2 | protein-O-mannosyltransferase 2 |
| PROSER1 | proline and serine rich 1 |
| PRR3 | proline rich 3 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) |
| PTPN9 | protein tyrosine phosphatase, non-receptor type 9 |
| RARS | arginyl-tRNA synthetase |
| RBM42 | RNA binding motif protein 42 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RNF121 | ring finger protein 121 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| SCAMP5 | secretory carrier membrane protein 5 |
| SLC12A7 | solute carrier family 12 (potassium/chloride transporter), member 7 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| SLC25A15 | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 |
| SNTA1 | syntrophin, alpha 1 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| SREBF1 | sterol regulatory element binding transcription factor 1 |
| STX5 | syntaxin 5 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) |
| TGIF2 | TGFB-induced factor homeobox 2 |
| TMEM104 | transmembrane protein 104 |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TTLL12 | tubulin tyrosine ligase-like family member 12 |
| TXLNG | taxilin gamma |
| TXNL4B | thioredoxin-like 4B |
| UBE2O | ubiquitin-conjugating enzyme E2O |
| UTP20 | UTP20, small subunit (SSU) processome component, homolog (yeast) |
| WDR3 | WD repeat domain 3 |
| YRDC | yrdC N(6)-threonylcarbamoyltransferase domain containing |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZDHHC18 | zinc finger, DHHC-type containing 18 |
| ZNF143 | zinc finger protein 143 |
| ZNF324 | zinc finger protein 324 |
| ZNF408 | zinc finger protein 408 |
| ZNF574 | zinc finger protein 574 |
