| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the sirolimus-1221 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACVR2B | activin A receptor, type IIB |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) |
| ARMC8 | armadillo repeat containing 8 |
| ATP9A | ATPase, class II, type 9A |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) |
| BTBD7 | BTB (POZ) domain containing 7 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| C1ORF95 | chromosome 1 open reading frame 95 |
| C21ORF2 | chromosome 21 open reading frame 2 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CACNB3 | calcium channel, voltage-dependent, beta 3 subunit |
| CADM3 | cell adhesion molecule 3 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CCDC9 | coiled-coil domain containing 9 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CEP162 | centrosomal protein 162kDa |
| CEP97 | centrosomal protein 97kDa |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| CNPPD1 | cyclin Pas1/PHO80 domain containing 1 |
| COL6A1 | collagen, type VI, alpha 1 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| DIDO1 | death inducer-obliterator 1 |
| DSCAM | Down syndrome cell adhesion molecule |
| DSTYK | dual serine/threonine and tyrosine protein kinase |
| DUSP4 | dual specificity phosphatase 4 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 |
| EMP1 | epithelial membrane protein 1 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| FAM204A | family with sequence similarity 204, member A |
| FGF13 | fibroblast growth factor 13 |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GPATCH2L | G patch domain containing 2-like |
| GRB7 | growth factor receptor-bound protein 7 |
| H2AFJ | H2A histone family, member J |
| HAMP | hepcidin antimicrobial peptide |
| HAUS5 | HAUS augmin-like complex, subunit 5 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H4D | histone cluster 1, H4d |
| HMOX1 | heme oxygenase 1 |
| HPS4 | Hermansky-Pudlak syndrome 4 |
| ING4 | inhibitor of growth family, member 4 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KLHL24 | kelch-like family member 24 |
| LRRK1 | leucine-rich repeat kinase 1 |
| MSL3 | male-specific lethal 3 homolog (Drosophila) |
| MT2A | metallothionein 2A |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NNMT | nicotinamide N-methyltransferase |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| PGAP1 | post-GPI attachment to proteins 1 |
| PGPEP1 | pyroglutamyl-peptidase I |
| PHF3 | PHD finger protein 3 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| PPP1R7 | protein phosphatase 1, regulatory subunit 7 |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
| PTGES | prostaglandin E synthase |
| RAB31 | RAB31, member RAS oncogene family |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 |
| RB1CC1 | RB1-inducible coiled-coil 1 |
| RGS14 | regulator of G-protein signaling 14 |
| RNASE4 | ribonuclease, RNase A family, 4 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLC25A30 | solute carrier family 25, member 30 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 |
| SPATA6 | spermatogenesis associated 6 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 |
| STON1 | stonin 1 |
| SUPT20H | suppressor of Ty 20 homolog (S. cerevisiae) |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TNFSF15 | tumor necrosis factor (ligand) superfamily, member 15 |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| TRIM25 | tripartite motif containing 25 |
| TRIM29 | tripartite motif containing 29 |
| TTC30A | tetratricopeptide repeat domain 30A |
| VN1R1 | vomeronasal 1 receptor 1 |
| VWA5A | von Willebrand factor A domain containing 5A |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZC3H13 | zinc finger CCCH-type containing 13 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF667 | zinc finger protein 667 |
| ZNF783 | zinc finger family member 783 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| AEN | apoptosis enhancing nuclease |
| ANKEF1 | ankyrin repeat and EF-hand domain containing 1 |
| ARSJ | arylsulfatase family, member J |
| BAK1 | BCL2-antagonist/killer 1 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| BMP4 | bone morphogenetic protein 4 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| CCDC86 | coiled-coil domain containing 86 |
| CHKA | choline kinase alpha |
| COBL | cordon-bleu WH2 repeat protein |
| COPS7B | COP9 signalosome subunit 7B |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CTPS1 | CTP synthase 1 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 |
| DNM1 | dynamin 1 |
| DVL1 | dishevelled segment polarity protein 1 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EFNA3 | ephrin-A3 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 |
| EHD3 | EH-domain containing 3 |
| ELAVL2 | ELAV like neuron-specific RNA binding protein 2 |
| EXTL2 | exostosin-like glycosyltransferase 2 |
| FAM50B | family with sequence similarity 50, member B |
| FOXC1 | forkhead box C1 |
| FUZ | fuzzy planar cell polarity protein |
| GBX2 | gastrulation brain homeobox 2 |
| GDAP2 | ganglioside induced differentiation associated protein 2 |
| GLCE | glucuronic acid epimerase |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GRAMD3 | GRAM domain containing 3 |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| IL17RA | interleukin 17 receptor A |
| INPPL1 | inositol polyphosphate phosphatase-like 1 |
| KIAA0513 | KIAA0513 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAGEH1 | melanoma antigen family H1 |
| MAK16 | MAK16 homolog (S. cerevisiae) |
| MAP6D1 | MAP6 domain containing 1 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 |
| METTL8 | methyltransferase like 8 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MOB3B | MOB kinase activator 3B |
| MOXD1 | monooxygenase, DBH-like 1 |
| MPP1 | membrane protein, palmitoylated 1, 55kDa |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| NAA16 | N(alpha)-acetyltransferase 16, NatA auxiliary subunit |
| NARFL | nuclear prelamin A recognition factor-like |
| NDUFAF4 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 |
| NOC3L | nucleolar complex associated 3 homolog (S. cerevisiae) |
| NOP2 | NOP2 nucleolar protein |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| NUDT3 | nudix (nucleoside diphosphate linked moiety X)-type motif 3 |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PCBP4 | poly(rC) binding protein 4 |
| PDSS1 | prenyl (decaprenyl) diphosphate synthase, subunit 1 |
| PEX11A | peroxisomal biogenesis factor 11 alpha |
| PHGDH | phosphoglycerate dehydrogenase |
| PISD | phosphatidylserine decarboxylase |
| PMM2 | phosphomannomutase 2 |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| POLR3K | polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRKRIR | protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) |
| PRPF38B | pre-mRNA processing factor 38B |
| RABEPK | Rab9 effector protein with kelch motifs |
| RARS | arginyl-tRNA synthetase |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RNF25 | ring finger protein 25 |
| RPP40 | ribonuclease P/MRP 40kDa subunit |
| RRP1 | ribosomal RNA processing 1 |
| SIRT2 | sirtuin 2 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SLC25A38 | solute carrier family 25, member 38 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SOWAHC | sosondowah ankyrin repeat domain family member C |
| SPATA2L | spermatogenesis associated 2-like |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| STEAP3 | STEAP family member 3, metalloreductase |
| STIM1 | stromal interaction molecule 1 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMEM242 | transmembrane protein 242 |
| TMEM40 | transmembrane protein 40 |
| TRAIP | TRAF interacting protein |
| TRMT12 | tRNA methyltransferase 12 homolog (S. cerevisiae) |
| WDR3 | WD repeat domain 3 |
| WDR43 | WD repeat domain 43 |
| WDR46 | WD repeat domain 46 |
| WDR74 | WD repeat domain 74 |
| YRDC | yrdC N(6)-threonylcarbamoyltransferase domain containing |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZNF143 | zinc finger protein 143 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
