| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the sirolimus-1242 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAMDC | adipogenesis associated, Mth938 domain containing |
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| ANXA10 | annexin A10 |
| ATP13A2 | ATPase type 13A2 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| BBC3 | BCL2 binding component 3 |
| BCL2L11 | BCL2-like 11 (apoptosis facilitator) |
| C11ORF71 | chromosome 11 open reading frame 71 |
| C1RL | complement component 1, r subcomponent-like |
| C5 | complement component 5 |
| CALHM2 | calcium homeostasis modulator 2 |
| CAPN10 | calpain 10 |
| CCNG2 | cyclin G2 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CUL7 | cullin 7 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 |
| DIDO1 | death inducer-obliterator 1 |
| DLX2 | distal-less homeobox 2 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| EGR1 | early growth response 1 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) |
| EZH1 | enhancer of zeste 1 polycomb repressive complex 2 subunit |
| FAM134B | family with sequence similarity 134, member B |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| H2AFX | H2A histone family, member X |
| HBP1 | HMG-box transcription factor 1 |
| HEMK1 | HemK methyltransferase family member 1 |
| IGF1R | insulin-like growth factor 1 receptor |
| IL15 | interleukin 15 |
| ING4 | inhibitor of growth family, member 4 |
| ITGB4 | integrin, beta 4 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 |
| KLF6 | Kruppel-like factor 6 |
| KLHL24 | kelch-like family member 24 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| MT1F | metallothionein 1F |
| MT1X | metallothionein 1X |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NLE1 | notchless homolog 1 (Drosophila) |
| NNMT | nicotinamide N-methyltransferase |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| OGFR | opioid growth factor receptor |
| OPCML | opioid binding protein/cell adhesion molecule-like |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| PGAP1 | post-GPI attachment to proteins 1 |
| PHF3 | PHD finger protein 3 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PLD1 | phospholipase D1, phosphatidylcholine-specific |
| PLD3 | phospholipase D family, member 3 |
| PLSCR4 | phospholipid scramblase 4 |
| POU2F3 | POU class 2 homeobox 3 |
| PTHLH | parathyroid hormone-like hormone |
| PTN | pleiotrophin |
| RERE | arginine-glutamic acid dipeptide (RE) repeats |
| RNF216 | ring finger protein 216 |
| ROR1 | receptor tyrosine kinase-like orphan receptor 1 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SOX10 | SRY (sex determining region Y)-box 10 |
| SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 |
| SSX3 | synovial sarcoma, X breakpoint 3 |
| STON1 | stonin 1 |
| TBC1D17 | TBC1 domain family, member 17 |
| TDRKH | tudor and KH domain containing |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| THRB | thyroid hormone receptor, beta |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TMEM209 | transmembrane protein 209 |
| TNFSF15 | tumor necrosis factor (ligand) superfamily, member 15 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TRABD | TraB domain containing |
| TRIM25 | tripartite motif containing 25 |
| TRIM45 | tripartite motif containing 45 |
| ULK1 | unc-51 like autophagy activating kinase 1 |
| VCAN | versican |
| WDR25 | WD repeat domain 25 |
| WDR45 | WD repeat domain 45 |
| WFDC2 | WAP four-disulfide core domain 2 |
| WIPI2 | WD repeat domain, phosphoinositide interacting 2 |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZNF197 | zinc finger protein 197 |
| ZNF287 | zinc finger protein 287 |
| ZNF7 | zinc finger protein 7 |
| ZNF767P | zinc finger family member 767, pseudogene |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| ABHD8 | abhydrolase domain containing 8 |
| ADAMTS3 | ADAM metallopeptidase with thrombospondin type 1 motif, 3 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARMC6 | armadillo repeat containing 6 |
| ATAD3A | ATPase family, AAA domain containing 3A |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| BCHE | butyrylcholinesterase |
| BTBD2 | BTB (POZ) domain containing 2 |
| BYSL | bystin-like |
| C10ORF2 | chromosome 10 open reading frame 2 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| CCDC86 | coiled-coil domain containing 86 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHEK2 | checkpoint kinase 2 |
| CLUH | clustered mitochondria (cluA/CLU1) homolog |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| COA7 | cytochrome c oxidase assembly factor 7 (putative) |
| CORO1A | coronin, actin binding protein, 1A |
| CTPS1 | CTP synthase 1 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DMTN | dematin actin binding protein |
| EAF2 | ELL associated factor 2 |
| EFNA3 | ephrin-A3 |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FAM102A | family with sequence similarity 102, member A |
| FAM169A | family with sequence similarity 169, member A |
| FAM184A | family with sequence similarity 184, member A |
| FKBPL | FK506 binding protein like |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GPR1 | G protein-coupled receptor 1 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 |
| HERC2P3 | hect domain and RLD 2 pseudogene 3 |
| HOXA1 | homeobox A1 |
| HSPA4L | heat shock 70kDa protein 4-like |
| IL17RA | interleukin 17 receptor A |
| ISL1 | ISL LIM homeobox 1 |
| KIAA0895 | KIAA0895 |
| KRT4 | keratin 4, type II |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| MANEA | mannosidase, endo-alpha |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MCC | mutated in colorectal cancers |
| METTL1 | methyltransferase like 1 |
| MOCS3 | molybdenum cofactor synthesis 3 |
| NDP | Norrie disease (pseudoglioma) |
| NOC3L | nucleolar complex associated 3 homolog (S. cerevisiae) |
| NOP2 | NOP2 nucleolar protein |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 |
| OXTR | oxytocin receptor |
| PARM1 | prostate androgen-regulated mucin-like protein 1 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 |
| PC | pyruvate carboxylase |
| PDSS1 | prenyl (decaprenyl) diphosphate synthase, subunit 1 |
| PEX11A | peroxisomal biogenesis factor 11 alpha |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PMM2 | phosphomannomutase 2 |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PTX3 | pentraxin 3, long |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RAB23 | RAB23, member RAS oncogene family |
| RABEPK | Rab9 effector protein with kelch motifs |
| RANBP17 | RAN binding protein 17 |
| RARS | arginyl-tRNA synthetase |
| RNF122 | ring finger protein 122 |
| SECTM1 | secreted and transmembrane 1 |
| SETBP1 | SET binding protein 1 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| SLC25A32 | solute carrier family 25 (mitochondrial folate carrier), member 32 |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SMYD5 | SMYD family member 5 |
| SYNPO | synaptopodin |
| TMEM104 | transmembrane protein 104 |
| TMEM40 | transmembrane protein 40 |
| TRAIP | TRAF interacting protein |
| TRIM9 | tripartite motif containing 9 |
| TRMT12 | tRNA methyltransferase 12 homolog (S. cerevisiae) |
| TSPAN15 | tetraspanin 15 |
| TSSC4 | tumor suppressing subtransferable candidate 4 |
| TTLL12 | tubulin tyrosine ligase-like family member 12 |
| TUBA3C | tubulin, alpha 3c |
| WDR3 | WD repeat domain 3 |
| WDR43 | WD repeat domain 43 |
| ZNF143 | zinc finger protein 143 |
| ZNF254 | zinc finger protein 254 |
| ZNF286A | zinc finger protein 286A |
| ZNF324 | zinc finger protein 324 |
| ZNF408 | zinc finger protein 408 |
