| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the sirolimus-1632 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD2 | abhydrolase domain containing 2 |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ADCK3 | aarF domain containing kinase 3 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| ATP9A | ATPase, class II, type 9A |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| BEX4 | brain expressed, X-linked 4 |
| BFSP1 | beaded filament structural protein 1, filensin |
| BTBD7 | BTB (POZ) domain containing 7 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C20ORF27 | chromosome 20 open reading frame 27 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase |
| CDC25C | cell division cycle 25C |
| CSNK1G2 | casein kinase 1, gamma 2 |
| CTAGE5 | CTAGE family, member 5 |
| CTH | cystathionine gamma-lyase |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DLX2 | distal-less homeobox 2 |
| EGFR | epidermal growth factor receptor |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| EXPH5 | exophilin 5 |
| FBXO9 | F-box protein 9 |
| FSCN1 | fascin actin-bundling protein 1 |
| FZD1 | frizzled class receptor 1 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GPR19 | G protein-coupled receptor 19 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit |
| HBP1 | HMG-box transcription factor 1 |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HLA-G | major histocompatibility complex, class I, G |
| HRASLS2 | HRAS-like suppressor 2 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IFI35 | interferon-induced protein 35 |
| IGL | immunoglobulin lambda locus |
| IQCK | IQ motif containing K |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) |
| KDM6A | lysine (K)-specific demethylase 6A |
| KIF13B | kinesin family member 13B |
| KLHL24 | kelch-like family member 24 |
| LMAN1 | lectin, mannose-binding, 1 |
| LOC647070 | uncharacterized LOC647070 |
| MECOM | MDS1 and EVI1 complex locus |
| MR1 | major histocompatibility complex, class I-related |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| NPPA | natriuretic peptide A |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NXT2 | nuclear transport factor 2-like export factor 2 |
| OLFML2A | olfactomedin-like 2A |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| POLL | polymerase (DNA directed), lambda |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha |
| PRDX2 | peroxiredoxin 2 |
| PRLR | prolactin receptor |
| PRRG2 | proline rich Gla (G-carboxyglutamic acid) 2 |
| PTCH1 | patched 1 |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RAD51B | RAD51 paralog B |
| RBM12 | RNA binding motif protein 12 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RPS2 | ribosomal protein S2 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SASH1 | SAM and SH3 domain containing 1 |
| SIDT1 | SID1 transmembrane family, member 1 |
| SIX1 | SIX homeobox 1 |
| SPHK2 | sphingosine kinase 2 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 |
| SRI | sorcin |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STAB2 | stabilin 2 |
| SULF1 | sulfatase 1 |
| TARS2 | threonyl-tRNA synthetase 2, mitochondrial (putative) |
| TESC | tescalcin |
| TGFB3 | transforming growth factor, beta 3 |
| TPR | translocated promoter region, nuclear basket protein |
| TREX1 | three prime repair exonuclease 1 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TSC22D4 | TSC22 domain family, member 4 |
| TXNIP | thioredoxin interacting protein |
| VN1R1 | vomeronasal 1 receptor 1 |
| WDR25 | WD repeat domain 25 |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase |
| ZBTB43 | zinc finger and BTB domain containing 43 |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZNF33B | zinc finger protein 33B |
| ZNF350 | zinc finger protein 350 |
| ZNF419 | zinc finger protein 419 |
| Symbol | Name |
|---|---|
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
| BCL7B | B-cell CLL/lymphoma 7B |
| BCORL1 | BCL6 corepressor-like 1 |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CCDC9 | coiled-coil domain containing 9 |
| CEP72 | centrosomal protein 72kDa |
| CERK | ceramide kinase |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CRY2 | cryptochrome circadian clock 2 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DHX16 | DEAH (Asp-Glu-Ala-His) box polypeptide 16 |
| DPH2 | DPH2 homolog (S. cerevisiae) |
| DSE | dermatan sulfate epimerase |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| ENTPD6 | ectonucleoside triphosphate diphosphohydrolase 6 (putative) |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FPGS | folylpolyglutamate synthase |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| FXR2 | fragile X mental retardation, autosomal homolog 2 |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GAN | gigaxonin |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| HAUS6 | HAUS augmin-like complex, subunit 6 |
| HCFC2 | host cell factor C2 |
| HDAC4 | histone deacetylase 4 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HOMER1 | homer scaffolding protein 1 |
| IFRD1 | interferon-related developmental regulator 1 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KIAA0125 | KIAA0125 |
| KLHL21 | kelch-like family member 21 |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| METTL1 | methyltransferase like 1 |
| MIR22HG | MIR22 host gene |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MVD | mevalonate (diphospho) decarboxylase |
| NCAM2 | neural cell adhesion molecule 2 |
| NDUFAF4 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NUPL2 | nucleoporin like 2 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PADI2 | peptidyl arginine deiminase, type II |
| PARG | poly (ADP-ribose) glycohydrolase |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PMM2 | phosphomannomutase 2 |
| POMZP3 | POM121 and ZP3 fusion |
| PPM1E | protein phosphatase, Mg2+/Mn2+ dependent, 1E |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PTK6 | protein tyrosine kinase 6 |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RGS19 | regulator of G-protein signaling 19 |
| RNF121 | ring finger protein 121 |
| RRP15 | ribosomal RNA processing 15 homolog (S. cerevisiae) |
| SARS2 | seryl-tRNA synthetase 2, mitochondrial |
| SCAMP4 | secretory carrier membrane protein 4 |
| SDCCAG3 | serologically defined colon cancer antigen 3 |
| SF3A3 | splicing factor 3a, subunit 3, 60kDa |
| SHPK | sedoheptulokinase |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| SNHG20 | small nucleolar RNA host gene 20 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPATA2L | spermatogenesis associated 2-like |
| SPHK1 | sphingosine kinase 1 |
| STK16 | serine/threonine kinase 16 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| THOP1 | thimet oligopeptidase 1 |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TWF2 | twinfilin actin binding protein 2 |
| VEGFC | vascular endothelial growth factor C |
| VPS4A | vacuolar protein sorting 4 homolog A (S. cerevisiae) |
| VWA1 | von Willebrand factor A domain containing 1 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZDHHC18 | zinc finger, DHHC-type containing 18 |
| ZNF205 | zinc finger protein 205 |
| ZNF324 | zinc finger protein 324 |
| ZNF331 | zinc finger protein 331 |
| ZNF787 | zinc finger protein 787 |
