| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the sirolimus-1646 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AHNAK2 | AHNAK nucleoprotein 2 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| ALS2CL | ALS2 C-terminal like |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BLVRA | biliverdin reductase A |
| BOLA1 | bolA family member 1 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CABIN1 | calcineurin binding protein 1 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CCDC28A | coiled-coil domain containing 28A |
| CCNG2 | cyclin G2 |
| CDK12 | cyclin-dependent kinase 12 |
| CDK17 | cyclin-dependent kinase 17 |
| CEP162 | centrosomal protein 162kDa |
| CEP68 | centrosomal protein 68kDa |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CSNK1E | casein kinase 1, epsilon |
| CTH | cystathionine gamma-lyase |
| DSCAM | Down syndrome cell adhesion molecule |
| DTNA | dystrobrevin, alpha |
| ESR1 | estrogen receptor 1 |
| EXOSC2 | exosome component 2 |
| FAS | Fas cell surface death receptor |
| FBXO2 | F-box protein 2 |
| GPER1 | G protein-coupled estrogen receptor 1 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HIST1H2AI | histone cluster 1, H2ai |
| HOXA4 | homeobox A4 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFITM1 | interferon induced transmembrane protein 1 |
| ING4 | inhibitor of growth family, member 4 |
| IRF9 | interferon regulatory factor 9 |
| ISG15 | ISG15 ubiquitin-like modifier |
| ITGB5 | integrin, beta 5 |
| KATNB1 | katanin p80 (WD repeat containing) subunit B 1 |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| KLHL24 | kelch-like family member 24 |
| LPXN | leupaxin |
| MAPK13 | mitogen-activated protein kinase 13 |
| MSL3 | male-specific lethal 3 homolog (Drosophila) |
| MT1X | metallothionein 1X |
| MTAP | methylthioadenosine phosphorylase |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| MYO10 | myosin X |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NFYA | nuclear transcription factor Y, alpha |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OTUD4 | OTU deubiquitinase 4 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| POFUT1 | protein O-fucosyltransferase 1 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha |
| RECQL5 | RecQ protein-like 5 |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| RNF208 | ring finger protein 208 |
| RPL10 | ribosomal protein L10 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RPL7 | ribosomal protein L7 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 |
| RTN2 | reticulon 2 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SH2B1 | SH2B adaptor protein 1 |
| SIRT3 | sirtuin 3 |
| SIRT5 | sirtuin 5 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SP100 | SP100 nuclear antigen |
| SP110 | SP110 nuclear body protein |
| SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 |
| SREBF2 | sterol regulatory element binding transcription factor 2 |
| TAPBP | TAP binding protein (tapasin) |
| TCTA | T-cell leukemia translocation altered |
| TLR5 | toll-like receptor 5 |
| TMEM80 | transmembrane protein 80 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TPMT | thiopurine S-methyltransferase |
| TREX1 | three prime repair exonuclease 1 |
| TXNIP | thioredoxin interacting protein |
| TXNL4B | thioredoxin-like 4B |
| UBE2H | ubiquitin-conjugating enzyme E2H |
| UTRN | utrophin |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| YTHDC1 | YTH domain containing 1 |
| ZBTB40 | zinc finger and BTB domain containing 40 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZNF442 | zinc finger protein 442 |
| Symbol | Name |
|---|---|
| AAR2 | AAR2 splicing factor homolog (S. cerevisiae) |
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
| ADGRA3 | adhesion G protein-coupled receptor A3 |
| AEN | apoptosis enhancing nuclease |
| ALDOC | aldolase C, fructose-bisphosphate |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ARMC6 | armadillo repeat containing 6 |
| ARNTL2 | aryl hydrocarbon receptor nuclear translocator-like 2 |
| BCL2L2 | BCL2-like 2 |
| C18ORF8 | chromosome 18 open reading frame 8 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CCND3 | cyclin D3 |
| CCNO | cyclin O |
| CEP72 | centrosomal protein 72kDa |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHPF | chondroitin polymerizing factor |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CORO1A | coronin, actin binding protein, 1A |
| CPTP | ceramide-1-phosphate transfer protein |
| CRY2 | cryptochrome circadian clock 2 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| EIF2B3 | eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| EPHA2 | EPH receptor A2 |
| EXOSC9 | exosome component 9 |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| GATA6 | GATA binding protein 6 |
| GHR | growth hormone receptor |
| GLB1L2 | galactosidase, beta 1-like 2 |
| GLCE | glucuronic acid epimerase |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| HCFC2 | host cell factor C2 |
| HECTD3 | HECT domain containing E3 ubiquitin protein ligase 3 |
| IFRD1 | interferon-related developmental regulator 1 |
| INSIG2 | insulin induced gene 2 |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KIAA0125 | KIAA0125 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MAP9 | microtubule-associated protein 9 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MED9 | mediator complex subunit 9 |
| MIR22HG | MIR22 host gene |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NPLOC4 | nuclear protein localization 4 homolog (S. cerevisiae) |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PARG | poly (ADP-ribose) glycohydrolase |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PLA2G15 | phospholipase A2, group XV |
| PLD3 | phospholipase D family, member 3 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| POMZP3 | POM121 and ZP3 fusion |
| PRR3 | proline rich 3 |
| PWP2 | PWP2 periodic tryptophan protein homolog (yeast) |
| RAI14 | retinoic acid induced 14 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RARS | arginyl-tRNA synthetase |
| RBBP5 | retinoblastoma binding protein 5 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
| SALL2 | spalt-like transcription factor 2 |
| SDCCAG3 | serologically defined colon cancer antigen 3 |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SNX15 | sorting nexin 15 |
| SRSF4 | serine/arginine-rich splicing factor 4 |
| SSFA2 | sperm specific antigen 2 |
| STBD1 | starch binding domain 1 |
| STEAP3 | STEAP family member 3, metalloreductase |
| SUSD4 | sushi domain containing 4 |
| THOP1 | thimet oligopeptidase 1 |
| TMEM104 | transmembrane protein 104 |
| TMEM127 | transmembrane protein 127 |
| TMEM183A | transmembrane protein 183A |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRABD | TraB domain containing |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 |
| WFS1 | Wolfram syndrome 1 (wolframin) |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZNF106 | zinc finger protein 106 |
| ZNF408 | zinc finger protein 408 |
| ZNF516 | zinc finger protein 516 |
| ZNF557 | zinc finger protein 557 |
| ZNF668 | zinc finger protein 668 |
| ZNF787 | zinc finger protein 787 |
| ZNF85 | zinc finger protein 85 |
| ZYX | zyxin |
