| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the sirolimus-2667 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM28 | ADAM metallopeptidase domain 28 |
| ADAMTS8 | ADAM metallopeptidase with thrombospondin type 1 motif, 8 |
| AHCYL1 | adenosylhomocysteinase-like 1 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 |
| ALK | anaplastic lymphoma receptor tyrosine kinase |
| APOE | apolipoprotein E |
| ARHGAP35 | Rho GTPase activating protein 35 |
| ARMC4 | armadillo repeat containing 4 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| CAPN2 | calpain 2, (m/II) large subunit |
| CD2 | CD2 molecule |
| CELA2A | chymotrypsin-like elastase family, member 2A |
| CES3 | carboxylesterase 3 |
| CHPF | chondroitin polymerizing factor |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CHST5 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 |
| CLPS | colipase, pancreatic |
| COLEC10 | collectin sub-family member 10 (C-type lectin) |
| CUL2 | cullin 2 |
| CYLC1 | cylicin, basic protein of sperm head cytoskeleton 1 |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| DGCR5 | DiGeorge syndrome critical region gene 5 (non-protein coding) |
| DGKG | diacylglycerol kinase, gamma 90kDa |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| ESM1 | endothelial cell-specific molecule 1 |
| F5 | coagulation factor V (proaccelerin, labile factor) |
| FCMR | Fc fragment of IgM receptor |
| FKBP9 | FK506 binding protein 9, 63 kDa |
| FLOT1 | flotillin 1 |
| FOXD2 | forkhead box D2 |
| FOXO4 | forkhead box O4 |
| GALC | galactosylceramidase |
| GJA4 | gap junction protein, alpha 4, 37kDa |
| GOLGA2P5 | golgin A2 pseudogene 5 |
| GPR35 | G protein-coupled receptor 35 |
| GRSF1 | G-rich RNA sequence binding factor 1 |
| GSPT1 | G1 to S phase transition 1 |
| HEMK1 | HemK methyltransferase family member 1 |
| HHIPL2 | HHIP-like 2 |
| HIST1H2BJ | histone cluster 1, H2bj |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like |
| HOXA11 | homeobox A11 |
| IFT54 | intraflagellar transport 54 |
| IGHM | immunoglobulin heavy constant mu |
| IL11 | interleukin 11 |
| IL24 | interleukin 24 |
| IL2RA | interleukin 2 receptor, alpha |
| IL3RA | interleukin 3 receptor, alpha (low affinity) |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| LILRA2 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 |
| LIMK2 | LIM domain kinase 2 |
| LOC647070 | uncharacterized LOC647070 |
| MCM3AP | minichromosome maintenance complex component 3 associated protein |
| MIIP | migration and invasion inhibitory protein |
| MKL2 | MKL/myocardin-like 2 |
| MPZL1 | myelin protein zero-like 1 |
| MTUS1 | microtubule associated tumor suppressor 1 |
| MUC1 | mucin 1, cell surface associated |
| MYBPC3 | myosin binding protein C, cardiac |
| NF1 | neurofibromin 1 |
| NINJ2 | ninjurin 2 |
| NLE1 | notchless homolog 1 (Drosophila) |
| NPEPL1 | aminopeptidase-like 1 |
| NPVF | neuropeptide VF precursor |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 |
| NRP2 | neuropilin 2 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| OR2H2 | olfactory receptor, family 2, subfamily H, member 2 |
| PAX5 | paired box 5 |
| PDLIM5 | PDZ and LIM domain 5 |
| PEG10 | paternally expressed 10 |
| PKNOX1 | PBX/knotted 1 homeobox 1 |
| PLD2 | phospholipase D2 |
| PRDM1 | PR domain containing 1, with ZNF domain |
| PRDM10 | PR domain containing 10 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 |
| RAB26 | RAB26, member RAS oncogene family |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 |
| RANBP1 | RAN binding protein 1 |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| SAFB | scaffold attachment factor B |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SIKE1 | suppressor of IKBKE 1 |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SOCS3 | suppressor of cytokine signaling 3 |
| SP110 | SP110 nuclear body protein |
| SSH3 | slingshot protein phosphatase 3 |
| TJP3 | tight junction protein 3 |
| TYMP | thymidine phosphorylase |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 |
| ZBTB20 | zinc finger and BTB domain containing 20 |
| ZFHX3 | zinc finger homeobox 3 |
| ZNF492 | zinc finger protein 492 |
| Symbol | Name |
|---|---|
| ACYP2 | acylphosphatase 2, muscle type |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| APBB1IP | amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| C8A | complement component 8, alpha polypeptide |
| C8ORF44 | chromosome 8 open reading frame 44 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CCDC109B | coiled-coil domain containing 109B |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CDKL1 | cyclin-dependent kinase-like 1 (CDC2-related kinase) |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLDN3 | claudin 3 |
| CNN1 | calponin 1, basic, smooth muscle |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CPNE7 | copine VII |
| CRYGC | crystallin, gamma C |
| CTH | cystathionine gamma-lyase |
| DBR1 | debranching RNA lariats 1 |
| DDN | dendrin |
| DENND5B | DENN/MADD domain containing 5B |
| DSPP | dentin sialophosphoprotein |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| FBRS | fibrosin |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) |
| GATA6 | GATA binding protein 6 |
| GPR68 | G protein-coupled receptor 68 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2AM | histone cluster 1, H2am |
| HIST1H2BN | histone cluster 1, H2bn |
| HIST1H3B | histone cluster 1, H3b |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HPR | haptoglobin-related protein |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| INHBE | inhibin, beta E |
| KDM8 | lysine (K)-specific demethylase 8 |
| KHDRBS2 | KH domain containing, RNA binding, signal transduction associated 2 |
| KIAA1456 | KIAA1456 |
| KLF3 | Kruppel-like factor 3 (basic) |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) |
| KRT81 | keratin 81, type II |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
| MEGF8 | multiple EGF-like-domains 8 |
| MPZ | myelin protein zero |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like |
| MX2 | MX dynamin-like GTPase 2 |
| NABP2 | nucleic acid binding protein 2 |
| NAG18 | NAG18 mRNA |
| NCS1 | neuronal calcium sensor 1 |
| NNAT | neuronatin |
| NSD1 | nuclear receptor binding SET domain protein 1 |
| NXF2 | nuclear RNA export factor 2 |
| OCLN | occludin |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PIGH | phosphatidylinositol glycan anchor biosynthesis, class H |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 |
| PPM1E | protein phosphatase, Mg2+/Mn2+ dependent, 1E |
| RAB33B | RAB33B, member RAS oncogene family |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RFXAP | regulatory factor X-associated protein |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SERPINI2 | serpin peptidase inhibitor, clade I (pancpin), member 2 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC16A6 | solute carrier family 16, member 6 |
| SNX16 | sorting nexin 16 |
| SPAG4 | sperm associated antigen 4 |
| SPATA1 | spermatogenesis associated 1 |
| SPRYD7 | SPRY domain containing 7 |
| SV2A | synaptic vesicle glycoprotein 2A |
| SYTL2 | synaptotagmin-like 2 |
| TAGLN | transgelin |
| TBC1D17 | TBC1 domain family, member 17 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TIGD6 | tigger transposable element derived 6 |
| TMEM212 | transmembrane protein 212 |
| TTC33 | tetratricopeptide repeat domain 33 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| UPB1 | ureidopropionase, beta |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VEGFC | vascular endothelial growth factor C |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |
