| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the sirolimus-2681 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A4GNT | alpha-1,4-N-acetylglucosaminyltransferase |
| ACTN2 | actinin, alpha 2 |
| ADCY2 | adenylate cyclase 2 (brain) |
| AHCYL1 | adenosylhomocysteinase-like 1 |
| ALOX5 | arachidonate 5-lipoxygenase |
| APOE | apolipoprotein E |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha |
| ASCL1 | achaete-scute family bHLH transcription factor 1 |
| ATP6AP2 | ATPase, H+ transporting, lysosomal accessory protein 2 |
| ATP9A | ATPase, class II, type 9A |
| C16ORF45 | chromosome 16 open reading frame 45 |
| CAV2 | caveolin 2 |
| CCDC85C | coiled-coil domain containing 85C |
| CCL19 | chemokine (C-C motif) ligand 19 |
| CD300C | CD300c molecule |
| CDH10 | cadherin 10, type 2 (T2-cadherin) |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) |
| CEACAM3 | carcinoembryonic antigen-related cell adhesion molecule 3 |
| CES3 | carboxylesterase 3 |
| CFHR4 | complement factor H-related 4 |
| CLEC1B | C-type lectin domain family 1, member B |
| COL11A2 | collagen, type XI, alpha 2 |
| CREBZF | CREB/ATF bZIP transcription factor |
| CST2 | cystatin SA |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| DGKG | diacylglycerol kinase, gamma 90kDa |
| EMC3 | ER membrane protein complex subunit 3 |
| EPYC | epiphycan |
| FLOT1 | flotillin 1 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| FOXG1 | forkhead box G1 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GLRA1 | glycine receptor, alpha 1 |
| GNB3 | guanine nucleotide binding protein (G protein), beta polypeptide 3 |
| GPATCH4 | G patch domain containing 4 |
| GPR37L1 | G protein-coupled receptor 37 like 1 |
| GRIK2 | glutamate receptor, ionotropic, kainate 2 |
| GRIN1 | glutamate receptor, ionotropic, N-methyl D-aspartate 1 |
| GRK4 | G protein-coupled receptor kinase 4 |
| GRM4 | glutamate receptor, metabotropic 4 |
| GRPR | gastrin-releasing peptide receptor |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| HEG1 | heart development protein with EGF-like domains 1 |
| HPSE2 | heparanase 2 (inactive) |
| HR | hair growth associated |
| ICAM1 | intercellular adhesion molecule 1 |
| IFIH1 | interferon induced with helicase C domain 1 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| ITGB4 | integrin, beta 4 |
| JPH3 | junctophilin 3 |
| KIF24 | kinesin family member 24 |
| KIF25 | kinesin family member 25 |
| LAT2 | linker for activation of T cells family, member 2 |
| LRRC6 | leucine rich repeat containing 6 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 |
| MAP9 | microtubule-associated protein 9 |
| MAX | MYC associated factor X |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MEP1B | meprin A, beta |
| MIIP | migration and invasion inhibitory protein |
| MIR622 | microRNA 622 |
| MOBP | myelin-associated oligodendrocyte basic protein |
| MROH7 | maestro heat-like repeat family member 7 |
| MTUS1 | microtubule associated tumor suppressor 1 |
| MYT1 | myelin transcription factor 1 |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NMU | neuromedin U |
| NPAS2 | neuronal PAS domain protein 2 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| NUP50 | nucleoporin 50kDa |
| OMG | oligodendrocyte myelin glycoprotein |
| PCDHGA8 | protocadherin gamma subfamily A, 8 |
| PHKG1 | phosphorylase kinase, gamma 1 (muscle) |
| PIN1P1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1 |
| PTPRF | protein tyrosine phosphatase, receptor type, F |
| RAB6B | RAB6B, member RAS oncogene family |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| SPRR2B | small proline-rich protein 2B |
| SYNGR3 | synaptogyrin 3 |
| TAGLN3 | transgelin 3 |
| TAPT1 | transmembrane anterior posterior transformation 1 |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| THBD | thrombomodulin |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
| TRD | T cell receptor delta locus |
| TRIM25 | tripartite motif containing 25 |
| TRPS1 | trichorhinophalangeal syndrome I |
| TTLL4 | tubulin tyrosine ligase-like family member 4 |
| USH1C | Usher syndrome 1C (autosomal recessive, severe) |
| WDR59 | WD repeat domain 59 |
| WIZ | widely interspaced zinc finger motifs |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZNF362 | zinc finger protein 362 |
| ZNF385D | zinc finger protein 385D |
| Symbol | Name |
|---|---|
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 |
| APBB1IP | amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein |
| APOC4 | apolipoprotein C-IV |
| ARMC7 | armadillo repeat containing 7 |
| BCAR3 | breast cancer anti-estrogen resistance 3 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| C3 | complement component 3 |
| C8A | complement component 8, alpha polypeptide |
| C9ORF91 | chromosome 9 open reading frame 91 |
| CASS4 | Cas scaffolding protein family member 4 |
| CDK20 | cyclin-dependent kinase 20 |
| CDON | cell adhesion associated, oncogene regulated |
| CFP | complement factor properdin |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHRNA10 | cholinergic receptor, nicotinic, alpha 10 (neuronal) |
| CHRNA5 | cholinergic receptor, nicotinic, alpha 5 (neuronal) |
| CNN1 | calponin 1, basic, smooth muscle |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CTH | cystathionine gamma-lyase |
| DNM3 | dynamin 3 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| DYM | dymeclin |
| EPHB6 | EPH receptor B6 |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FAM102A | family with sequence similarity 102, member A |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| GALE | UDP-galactose-4-epimerase |
| GATA6 | GATA binding protein 6 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GCHFR | GTP cyclohydrolase I feedback regulator |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPR22 | G protein-coupled receptor 22 |
| GPR3 | G protein-coupled receptor 3 |
| GRB7 | growth factor receptor-bound protein 7 |
| HEYL | hes-related family bHLH transcription factor with YRPW motif-like |
| HOXA5 | homeobox A5 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| KCNA5 | potassium channel, voltage gated shaker related subfamily A, member 5 |
| KLK5 | kallikrein-related peptidase 5 |
| KPTN | kaptin (actin binding protein) |
| LPPR3 | lipid phosphate phosphatase-related protein type 3 |
| MEGF8 | multiple EGF-like-domains 8 |
| MTA2 | metastasis associated 1 family, member 2 |
| MXD3 | MAX dimerization protein 3 |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NARFL | nuclear prelamin A recognition factor-like |
| NCS1 | neuronal calcium sensor 1 |
| NDE1 | nudE neurodevelopment protein 1 |
| NEUROD4 | neuronal differentiation 4 |
| NKX3-2 | NK3 homeobox 2 |
| NLGN1 | neuroligin 1 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| P2RY11 | purinergic receptor P2Y, G-protein coupled, 11 |
| PADI2 | peptidyl arginine deiminase, type II |
| PBOV1 | prostate and breast cancer overexpressed 1 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| PGM3 | phosphoglucomutase 3 |
| PGP | phosphoglycolate phosphatase |
| PIAS3 | protein inhibitor of activated STAT, 3 |
| PLA2G15 | phospholipase A2, group XV |
| PMCH | pro-melanin-concentrating hormone |
| PRDM12 | PR domain containing 12 |
| PRKCZ | protein kinase C, zeta |
| PSAT1 | phosphoserine aminotransferase 1 |
| PSKH1 | protein serine kinase H1 |
| PYGB | phosphorylase, glycogen; brain |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| RWDD2A | RWD domain containing 2A |
| SCRN3 | secernin 3 |
| SH3PXD2A | SH3 and PX domains 2A |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC15A3 | solute carrier family 15 (oligopeptide transporter), member 3 |
| SLC35C2 | solute carrier family 35 (GDP-fucose transporter), member C2 |
| SNX15 | sorting nexin 15 |
| SREBF1 | sterol regulatory element binding transcription factor 1 |
| STC2 | stanniocalcin 2 |
| SYNPO2L | synaptopodin 2-like |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TAS2R10 | taste receptor, type 2, member 10 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 |
| TMEM104 | transmembrane protein 104 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TUFT1 | tuftelin 1 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| ZNF177 | zinc finger protein 177 |
| ZNF408 | zinc finger protein 408 |
| ZNF76 | zinc finger protein 76 |
| ZNF768 | zinc finger protein 768 |
