| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the sirolimus-2702 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAK1 | AP2 associated kinase 1 |
| AASS | aminoadipate-semialdehyde synthase |
| ACSM1 | acyl-CoA synthetase medium-chain family member 1 |
| ADAM20 | ADAM metallopeptidase domain 20 |
| ADAM3A | ADAM metallopeptidase domain 3A (pseudogene) |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| APOE | apolipoprotein E |
| ASPH | aspartate beta-hydroxylase |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| BGN | biglycan |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit |
| CD300C | CD300c molecule |
| CDH10 | cadherin 10, type 2 (T2-cadherin) |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
| COL5A1 | collagen, type V, alpha 1 |
| COPG2IT1 | COPG2 imprinted transcript 1 (non-protein coding) |
| CPT1A | carnitine palmitoyltransferase 1A (liver) |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CREM | cAMP responsive element modulator |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CYP2E1 | cytochrome P450, family 2, subfamily E, polypeptide 1 |
| DDR1 | discoidin domain receptor tyrosine kinase 1 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| EGOT | eosinophil granule ontogeny transcript (non-protein coding) |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) |
| EPHA5 | EPH receptor A5 |
| EPN2 | epsin 2 |
| EXPH5 | exophilin 5 |
| FDXR | ferredoxin reductase |
| FMO3 | flavin containing monooxygenase 3 |
| FNTB | farnesyltransferase, CAAX box, beta |
| FOXO4 | forkhead box O4 |
| GABRA1 | gamma-aminobutyric acid (GABA) A receptor, alpha 1 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GLE1 | GLE1 RNA export mediator |
| GLRA2 | glycine receptor, alpha 2 |
| GUCA2B | guanylate cyclase activator 2B (uroguanylin) |
| H6PD | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HTR7P1 | 5-hydroxytryptamine (serotonin) receptor 7 pseudogene 1 |
| HUS1 | HUS1 checkpoint homolog (S. pombe) |
| IL17RC | interleukin 17 receptor C |
| IL1R1 | interleukin 1 receptor, type I |
| JPH3 | junctophilin 3 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KCNE2 | potassium channel, voltage gated subfamily E regulatory beta subunit 2 |
| KCNH6 | potassium channel, voltage gated eag related subfamily H, member 6 |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| LAMC3 | laminin, gamma 3 |
| LBX1 | ladybird homeobox 1 |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| MAP9 | microtubule-associated protein 9 |
| MYO7A | myosin VIIA |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NID1 | nidogen 1 |
| NME8 | NME/NM23 family member 8 |
| NPC1 | Niemann-Pick disease, type C1 |
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 |
| OLFM4 | olfactomedin 4 |
| ONECUT2 | one cut homeobox 2 |
| PAX1 | paired box 1 |
| PCDHGA8 | protocadherin gamma subfamily A, 8 |
| PDE11A | phosphodiesterase 11A |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDLIM5 | PDZ and LIM domain 5 |
| PHF3 | PHD finger protein 3 |
| PHKG1 | phosphorylase kinase, gamma 1 (muscle) |
| PHTF2 | putative homeodomain transcription factor 2 |
| PLA2G3 | phospholipase A2, group III |
| PLCE1 | phospholipase C, epsilon 1 |
| PLXDC1 | plexin domain containing 1 |
| PP14571 | uncharacterized LOC100130449 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) |
| PRO2964 | uncharacterized protein PRO2964 |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RAB38 | RAB38, member RAS oncogene family |
| RBP4 | retinol binding protein 4, plasma |
| RPL3L | ribosomal protein L3-like |
| RPLP2 | ribosomal protein, large, P2 |
| SIT1 | signaling threshold regulating transmembrane adaptor 1 |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC35A2 | solute carrier family 35 (UDP-galactose transporter), member A2 |
| SORBS1 | sorbin and SH3 domain containing 1 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) |
| STK3 | serine/threonine kinase 3 |
| STON1 | stonin 1 |
| SULF1 | sulfatase 1 |
| SYT13 | synaptotagmin XIII |
| TESK1 | testis-specific kinase 1 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
| TRIM2 | tripartite motif containing 2 |
| USP6NL | USP6 N-terminal like |
| WNT8B | wingless-type MMTV integration site family, member 8B |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 |
| ZFHX3 | zinc finger homeobox 3 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF385D | zinc finger protein 385D |
| Symbol | Name |
|---|---|
| ACPP | acid phosphatase, prostate |
| ALOX12 | arachidonate 12-lipoxygenase |
| ANKRD55 | ankyrin repeat domain 55 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 |
| ARMC7 | armadillo repeat containing 7 |
| ASPN | asporin |
| BCAS3 | breast carcinoma amplified sequence 3 |
| BDKRB1 | bradykinin receptor B1 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| CCDC92 | coiled-coil domain containing 92 |
| CD160 | CD160 molecule |
| CDK20 | cyclin-dependent kinase 20 |
| CEMP1 | cementum protein 1 |
| CEP97 | centrosomal protein 97kDa |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLGN | calmegin |
| CLIP2 | CAP-GLY domain containing linker protein 2 |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| CORO2B | coronin, actin binding protein, 2B |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CST1 | cystatin SN |
| CTH | cystathionine gamma-lyase |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| GABARAPL3 | GABA(A) receptors associated protein like 3, pseudogene |
| GAREM | GRB2 associated, regulator of MAPK1 |
| GATA6 | GATA binding protein 6 |
| GID4 | GID complex subunit 4 |
| GPR22 | G protein-coupled receptor 22 |
| GPR3 | G protein-coupled receptor 3 |
| GTF2IRD1 | GTF2I repeat domain containing 1 |
| HIST1H1E | histone cluster 1, H1e |
| HRH2 | histamine receptor H2 |
| IBSP | integrin-binding sialoprotein |
| ICAM4 | intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) |
| IL12RB2 | interleukin 12 receptor, beta 2 |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| IRF7 | interferon regulatory factor 7 |
| IRS1 | insulin receptor substrate 1 |
| JAM3 | junctional adhesion molecule 3 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KANSL3 | KAT8 regulatory NSL complex subunit 3 |
| KCNA6 | potassium channel, voltage gated shaker related subfamily A, member 6 |
| KIAA1024 | KIAA1024 |
| KLK5 | kallikrein-related peptidase 5 |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LIMD2 | LIM domain containing 2 |
| MAK | male germ cell-associated kinase |
| MDM4 | MDM4, p53 regulator |
| MEFV | Mediterranean fever |
| MLPH | melanophilin |
| MREG | melanoregulin |
| MXD3 | MAX dimerization protein 3 |
| MYBPC1 | myosin binding protein C, slow type |
| MYH3 | myosin, heavy chain 3, skeletal muscle, embryonic |
| NBEA | neurobeachin |
| NEUROD1 | neuronal differentiation 1 |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PADI2 | peptidyl arginine deiminase, type II |
| PDGFRL | platelet-derived growth factor receptor-like |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PSAT1 | phosphoserine aminotransferase 1 |
| PYGB | phosphorylase, glycogen; brain |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RBM47 | RNA binding motif protein 47 |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RIN2 | Ras and Rab interactor 2 |
| RNF122 | ring finger protein 122 |
| RWDD2A | RWD domain containing 2A |
| SH3PXD2A | SH3 and PX domains 2A |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SMUG1 | single-strand-selective monofunctional uracil-DNA glycosylase 1 |
| STC2 | stanniocalcin 2 |
| SV2B | synaptic vesicle glycoprotein 2B |
| SYCP2 | synaptonemal complex protein 2 |
| TEX15 | testis expressed 15 |
| THBS3 | thrombospondin 3 |
| TMEM212 | transmembrane protein 212 |
| TMEM246 | transmembrane protein 246 |
| TMEM53 | transmembrane protein 53 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TPM3 | tropomyosin 3 |
| TRAF2 | TNF receptor-associated factor 2 |
| TSC22D4 | TSC22 domain family, member 4 |
| UNC13A | unc-13 homolog A (C. elegans) |
| VN1R1 | vomeronasal 1 receptor 1 |
| XKR8 | XK, Kell blood group complex subunit-related family, member 8 |
| ZNF276 | zinc finger protein 276 |
| ZNF528 | zinc finger protein 528 |
| ZNF76 | zinc finger protein 76 |
| ZNF768 | zinc finger protein 768 |
