| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the sirolimus-326 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABI1 | abl-interactor 1 |
| ACADM | acyl-CoA dehydrogenase, C-4 to C-12 straight chain |
| ACTN1 | actinin, alpha 1 |
| AFF1 | AF4/FMR2 family, member 1 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| ANKRD28 | ankyrin repeat domain 28 |
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like |
| ATOX1 | antioxidant 1 copper chaperone |
| ATP13A3 | ATPase type 13A3 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like |
| BTBD2 | BTB (POZ) domain containing 2 |
| C14ORF1 | chromosome 14 open reading frame 1 |
| C19ORF66 | chromosome 19 open reading frame 66 |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| C20ORF27 | chromosome 20 open reading frame 27 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CCBL2 | cysteine conjugate-beta lyase 2 |
| CCDC85C | coiled-coil domain containing 85C |
| CCNG2 | cyclin G2 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
| CFAP70 | cilia and flagella associated protein 70 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CLASP1 | cytoplasmic linker associated protein 1 |
| COBL | cordon-bleu WH2 repeat protein |
| CPOX | coproporphyrinogen oxidase |
| CUL4B | cullin 4B |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| ECE1 | endothelin converting enzyme 1 |
| EID1 | EP300 interacting inhibitor of differentiation 1 |
| ESR1 | estrogen receptor 1 |
| FASTK | Fas-activated serine/threonine kinase |
| FKBP8 | FK506 binding protein 8, 38kDa |
| FOXD1 | forkhead box D1 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GLG1 | golgi glycoprotein 1 |
| GPRC5C | G protein-coupled receptor, class C, group 5, member C |
| GRIP2 | glutamate receptor interacting protein 2 |
| HINFP | histone H4 transcription factor |
| HLA-G | major histocompatibility complex, class I, G |
| HMGN4 | high mobility group nucleosomal binding domain 4 |
| HSPB11 | heat shock protein family B (small), member 11 |
| ICA1 | islet cell autoantigen 1, 69kDa |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| ITM2B | integral membrane protein 2B |
| JAKMIP2 | janus kinase and microtubule interacting protein 2 |
| KDM4B | lysine (K)-specific demethylase 4B |
| KLHL24 | kelch-like family member 24 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| KTN1 | kinectin 1 (kinesin receptor) |
| L1CAM | L1 cell adhesion molecule |
| LAMP2 | lysosomal-associated membrane protein 2 |
| LIN7C | lin-7 homolog C (C. elegans) |
| MAP3K12 | mitogen-activated protein kinase kinase kinase 12 |
| MOAP1 | modulator of apoptosis 1 |
| MPPE1 | metallophosphoesterase 1 |
| MTF1 | metal-regulatory transcription factor 1 |
| MYL12B | myosin, light chain 12B, regulatory |
| NADK | NAD kinase |
| NDE1 | nudE neurodevelopment protein 1 |
| NDUFA1 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa |
| NEK1 | NIMA-related kinase 1 |
| NSMAF | neutral sphingomyelinase (N-SMase) activation associated factor |
| OLFM1 | olfactomedin 1 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme |
| PRPF39 | pre-mRNA processing factor 39 |
| PSMD5 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 |
| PTOV1 | prostate tumor overexpressed 1 |
| RAB40B | RAB40B, member RAS oncogene family |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 |
| RBL2 | retinoblastoma-like 2 |
| RHOD | ras homolog family member D |
| RPS2 | ribosomal protein S2 |
| SAP18 | Sin3A-associated protein, 18kDa |
| SCAMP1 | secretory carrier membrane protein 1 |
| SIGMAR1 | sigma non-opioid intracellular receptor 1 |
| SNAPC4 | small nuclear RNA activating complex, polypeptide 4, 190kDa |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| SSH3 | slingshot protein phosphatase 3 |
| SYT13 | synaptotagmin XIII |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 |
| TBC1D17 | TBC1 domain family, member 17 |
| TESK2 | testis-specific kinase 2 |
| TMEM161A | transmembrane protein 161A |
| TMSB4Y | thymosin beta 4, Y-linked |
| TRAC | T cell receptor alpha constant |
| TRIO | trio Rho guanine nucleotide exchange factor |
| TSPAN31 | tetraspanin 31 |
| URI1 | URI1, prefoldin-like chaperone |
| USF2 | upstream transcription factor 2, c-fos interacting |
| WAS | Wiskott-Aldrich syndrome |
| WWTR1 | WW domain containing transcription regulator 1 |
| YIPF2 | Yip1 domain family, member 2 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZFYVE26 | zinc finger, FYVE domain containing 26 |
| ZIC1 | Zic family member 1 |
| ZNF277 | zinc finger protein 277 |
| Symbol | Name |
|---|---|
| ABLIM3 | actin binding LIM protein family, member 3 |
| AIM2 | absent in melanoma 2 |
| AMN | amnion associated transmembrane protein |
| ARPC5L | actin related protein 2/3 complex, subunit 5-like |
| ATP1B2 | ATPase, Na+/K+ transporting, beta 2 polypeptide |
| C7ORF43 | chromosome 7 open reading frame 43 |
| C8B | complement component 8, beta polypeptide |
| CARTPT | CART prepropeptide |
| CAV3 | caveolin 3 |
| CCL21 | chemokine (C-C motif) ligand 21 |
| CD2 | CD2 molecule |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CHRNA5 | cholinergic receptor, nicotinic, alpha 5 (neuronal) |
| CHRNA9 | cholinergic receptor, nicotinic, alpha 9 (neuronal) |
| CORO2B | coronin, actin binding protein, 2B |
| CP | ceruloplasmin (ferroxidase) |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| DENND6B | DENN/MADD domain containing 6B |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DMTN | dematin actin binding protein |
| DSG3 | desmoglein 3 |
| DYNC1I1 | dynein, cytoplasmic 1, intermediate chain 1 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| ETV7 | ets variant 7 |
| EXOC2 | exocyst complex component 2 |
| EXOSC9 | exosome component 9 |
| FMO6P | flavin containing monooxygenase 6 pseudogene |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| FXYD6 | FXYD domain containing ion transport regulator 6 |
| GLRA2 | glycine receptor, alpha 2 |
| GMIP | GEM interacting protein |
| GMPR | guanosine monophosphate reductase |
| GNAT3 | guanine nucleotide binding protein, alpha transducing 3 |
| GPA33 | glycoprotein A33 (transmembrane) |
| GSTA3 | glutathione S-transferase alpha 3 |
| GTF2I | general transcription factor IIi |
| HIST1H3G | histone cluster 1, H3g |
| HIST1H3I | histone cluster 1, H3i |
| HTR6 | 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled |
| IDO1 | indoleamine 2,3-dioxygenase 1 |
| IFI35 | interferon-induced protein 35 |
| IL15RA | interleukin 15 receptor, alpha |
| IP6K1 | inositol hexakisphosphate kinase 1 |
| KIR2DS1 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 |
| KIR3DS1 | killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1 |
| KLHL3 | kelch-like family member 3 |
| LOC100127972 | uncharacterized LOC100127972 |
| LUZP4 | leucine zipper protein 4 |
| MAL | mal, T-cell differentiation protein |
| MED9 | mediator complex subunit 9 |
| MGC2889 | uncharacterized protein MGC2889 |
| MMP3 | matrix metallopeptidase 3 |
| MVP | major vault protein |
| MYH7 | myosin, heavy chain 7, cardiac muscle, beta |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NOX5 | NADPH oxidase, EF-hand calcium binding domain 5 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDE6A | phosphodiesterase 6A, cGMP-specific, rod, alpha |
| PDE8B | phosphodiesterase 8B |
| PFKFB1 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 |
| PHACTR4 | phosphatase and actin regulator 4 |
| PICK1 | protein interacting with PRKCA 1 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PRDM14 | PR domain containing 14 |
| PTPRN | protein tyrosine phosphatase, receptor type, N |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| PVRIG | poliovirus receptor related immunoglobulin domain containing |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 |
| RBP1 | retinol binding protein 1, cellular |
| RDH5 | retinol dehydrogenase 5 (11-cis/9-cis) |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RSPH6A | radial spoke head 6 homolog A (Chlamydomonas) |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SLC13A4 | solute carrier family 13 (sodium/sulfate symporter), member 4 |
| SLC35G2 | solute carrier family 35, member G2 |
| SPRR3 | small proline-rich protein 3 |
| SSTR4 | somatostatin receptor 4 |
| STAC | SH3 and cysteine rich domain |
| STARD8 | StAR-related lipid transfer (START) domain containing 8 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TBR1 | T-box, brain, 1 |
| TET3 | tet methylcytosine dioxygenase 3 |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| TMEM176A | transmembrane protein 176A |
| TMEM39B | transmembrane protein 39B |
| TMEM62 | transmembrane protein 62 |
| TMPRSS5 | transmembrane protease, serine 5 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| TSPAN32 | tetraspanin 32 |
| TSPO2 | translocator protein 2 |
| UCP1 | uncoupling protein 1 (mitochondrial, proton carrier) |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| WDR13 | WD repeat domain 13 |
| ZNF408 | zinc finger protein 408 |
| ZNF646 | zinc finger protein 646 |
