| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the sirolimus-362 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) |
| ABCD4 | ATP-binding cassette, sub-family D (ALD), member 4 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| ACVR1B | activin A receptor, type IB |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| AQP6 | aquaporin 6, kidney specific |
| ATP1B2 | ATPase, Na+/K+ transporting, beta 2 polypeptide |
| ATP5G2 | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) |
| AURKA | aurora kinase A |
| BRE | brain and reproductive organ-expressed (TNFRSF1A modulator) |
| C16ORF58 | chromosome 16 open reading frame 58 |
| CADM3 | cell adhesion molecule 3 |
| CARTPT | CART prepropeptide |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CD5 | CD5 molecule |
| CDHR2 | cadherin-related family member 2 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DIO2 | deiodinase, iodothyronine, type II |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta |
| ERMP1 | endoplasmic reticulum metallopeptidase 1 |
| FGFBP1 | fibroblast growth factor binding protein 1 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GBAP1 | glucosidase, beta, acid pseudogene 1 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 |
| GHRHR | growth hormone releasing hormone receptor |
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 |
| GLP1R | glucagon-like peptide 1 receptor |
| GLRA2 | glycine receptor, alpha 2 |
| GPR107 | G protein-coupled receptor 107 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 |
| HEATR6 | HEAT repeat containing 6 |
| HIF1AN | hypoxia inducible factor 1, alpha subunit inhibitor |
| HTRA1 | HtrA serine peptidase 1 |
| IL19 | interleukin 19 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KIFAP3 | kinesin-associated protein 3 |
| KIR2DS1 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 |
| KLHL25 | kelch-like family member 25 |
| KLHL28 | kelch-like family member 28 |
| KRT85 | keratin 85, type II |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LPP | LIM domain containing preferred translocation partner in lipoma |
| MAOA | monoamine oxidase A |
| MAOB | monoamine oxidase B |
| MAX | MYC associated factor X |
| MST1 | macrophage stimulating 1 |
| MYOC | myocilin, trabecular meshwork inducible glucocorticoid response |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NEU3 | sialidase 3 (membrane sialidase) |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 |
| NKIRAS2 | NFKB inhibitor interacting Ras-like 2 |
| NOTCH4 | notch 4 |
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 |
| OSBPL10 | oxysterol binding protein-like 10 |
| PDLIM4 | PDZ and LIM domain 4 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
| PKD2L1 | polycystic kidney disease 2-like 1 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
| POU2F2 | POU class 2 homeobox 2 |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta |
| PQLC3 | PQ loop repeat containing 3 |
| PRDM14 | PR domain containing 14 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RANBP17 | RAN binding protein 17 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 |
| RUNDC3A | RUN domain containing 3A |
| SCN5A | sodium channel, voltage gated, type V alpha subunit |
| SEC23IP | SEC23 interacting protein |
| SH3GL3 | SH3-domain GRB2-like 3 |
| SIM2 | single-minded family bHLH transcription factor 2 |
| SLC6A3 | solute carrier family 6 (neurotransmitter transporter), member 3 |
| SLC6A5 | solute carrier family 6 (neurotransmitter transporter), member 5 |
| SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal |
| STX1A | syntaxin 1A (brain) |
| STXBP5L | syntaxin binding protein 5-like |
| TCP10L | t-complex 10-like |
| TFE3 | transcription factor binding to IGHM enhancer 3 |
| TG | thyroglobulin |
| TGM3 | transglutaminase 3 |
| TMEM127 | transmembrane protein 127 |
| TMF1 | TATA element modulatory factor 1 |
| TMPRSS6 | transmembrane protease, serine 6 |
| TP53TG5 | TP53 target 5 |
| TP63 | tumor protein p63 |
| TP73-AS1 | TP73 antisense RNA 1 |
| TSPAN7 | tetraspanin 7 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| YLPM1 | YLP motif containing 1 |
| ZC3H13 | zinc finger CCCH-type containing 13 |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| ZNF473 | zinc finger protein 473 |
| Symbol | Name |
|---|---|
| ADM2 | adrenomedullin 2 |
| ADRA2B | adrenoceptor alpha 2B |
| AMN | amnion associated transmembrane protein |
| APOL6 | apolipoprotein L, 6 |
| APOLD1 | apolipoprotein L domain containing 1 |
| AQP8 | aquaporin 8 |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| ATXN2L | ataxin 2-like |
| AXIN1 | axin 1 |
| BCL7B | B-cell CLL/lymphoma 7B |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| C5ORF28 | chromosome 5 open reading frame 28 |
| CCNO | cyclin O |
| CD151 | CD151 molecule (Raph blood group) |
| CEP41 | centrosomal protein 41kDa |
| CFAP74 | cilia and flagella associated protein 74 |
| CLPB | ClpB homolog, mitochondrial AAA ATPase chaperonin |
| CMA1 | chymase 1, mast cell |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| COL4A3BP | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein |
| DDX47 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| ENTPD6 | ectonucleoside triphosphate diphosphohydrolase 6 (putative) |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM189B | family with sequence similarity 189, member B |
| FAM76A | family with sequence similarity 76, member A |
| FGGY | FGGY carbohydrate kinase domain containing |
| FOLR3 | folate receptor 3 (gamma) |
| FTCD | formimidoyltransferase cyclodeaminase |
| FZD4 | frizzled class receptor 4 |
| GLI3 | GLI family zinc finger 3 |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| GUCA1B | guanylate cyclase activator 1B (retina) |
| HAPLN2 | hyaluronan and proteoglycan link protein 2 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| HTR3B | 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic |
| IFITM3 | interferon induced transmembrane protein 3 |
| ITGB7 | integrin, beta 7 |
| KIR3DS1 | killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1 |
| LMTK1 | lemur tail kinase 1 |
| LRRC16A | leucine rich repeat containing 16A |
| LRRC48 | leucine rich repeat containing 48 |
| MCOLN1 | mucolipin 1 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MOCS2 | molybdenum cofactor synthesis 2 |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MRTO4 | mRNA turnover 4 homolog (S. cerevisiae) |
| MSMO1 | methylsterol monooxygenase 1 |
| MTCP1 | mature T-cell proliferation 1 |
| MVD | mevalonate (diphospho) decarboxylase |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
| NPC1L1 | NPC1-like 1 |
| NUP93 | nucleoporin 93kDa |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) |
| PAGR1 | PAXIP1 associated glutamate-rich protein 1 |
| PALM | paralemmin |
| PAX1 | paired box 1 |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PDZD7 | PDZ domain containing 7 |
| PICK1 | protein interacting with PRKCA 1 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 |
| PIGT | phosphatidylinositol glycan anchor biosynthesis, class T |
| PLEK2 | pleckstrin 2 |
| PMP22 | peripheral myelin protein 22 |
| PODNL1 | podocan-like 1 |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| PPP4C | protein phosphatase 4, catalytic subunit |
| PRKY | protein kinase, Y-linked, pseudogene |
| PROL1 | proline rich, lacrimal 1 |
| PRSS8 | protease, serine, 8 |
| PSG7 | pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene) |
| PTDSS2 | phosphatidylserine synthase 2 |
| PTPRT | protein tyrosine phosphatase, receptor type, T |
| QPRT | quinolinate phosphoribosyltransferase |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain |
| RNF144A | ring finger protein 144A |
| RNF186 | ring finger protein 186 |
| RPAP2 | RNA polymerase II associated protein 2 |
| RPH3A | rabphilin 3A |
| SEMA6B | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B |
| SETMAR | SET domain and mariner transposase fusion gene |
| SIL1 | SIL1 nucleotide exchange factor |
| SMA4 | glucuronidase, beta pseudogene |
| TET3 | tet methylcytosine dioxygenase 3 |
| TLR8 | toll-like receptor 8 |
| TMED1 | transmembrane emp24 protein transport domain containing 1 |
| TPM3 | tropomyosin 3 |
| TPSG1 | tryptase gamma 1 |
| TRABD | TraB domain containing |
| TTN | titin |
| TTPA | tocopherol (alpha) transfer protein |
| UCP1 | uncoupling protein 1 (mitochondrial, proton carrier) |
| ZNF557 | zinc finger protein 557 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
