| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the sirolimus-402 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADH6 | alcohol dehydrogenase 6 (class V) |
| ADRA2B | adrenoceptor alpha 2B |
| AGFG2 | ArfGAP with FG repeats 2 |
| AQP6 | aquaporin 6, kidney specific |
| ARHGEF15 | Rho guanine nucleotide exchange factor (GEF) 15 |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 |
| C17ORF59 | chromosome 17 open reading frame 59 |
| C1ORF61 | chromosome 1 open reading frame 61 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CAV3 | caveolin 3 |
| CCR2 | chemokine (C-C motif) receptor 2 |
| CD79A | CD79a molecule, immunoglobulin-associated alpha |
| CD82 | CD82 molecule |
| CD8B | CD8b molecule |
| CDKN2A | cyclin-dependent kinase inhibitor 2A |
| CFAP70 | cilia and flagella associated protein 70 |
| CHD2 | chromodomain helicase DNA binding protein 2 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) |
| CIITA | class II, major histocompatibility complex, transactivator |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLDN14 | claudin 14 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| COPG2IT1 | COPG2 imprinted transcript 1 (non-protein coding) |
| CYP2D6 | cytochrome P450, family 2, subfamily D, polypeptide 6 |
| CYP46A1 | cytochrome P450, family 46, subfamily A, polypeptide 1 |
| CYP4A11 | cytochrome P450, family 4, subfamily A, polypeptide 11 |
| DEFA4 | defensin, alpha 4, corticostatin |
| DENND3 | DENN/MADD domain containing 3 |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| EFNB3 | ephrin-B3 |
| EVPL | envoplakin |
| FN1 | fibronectin 1 |
| FUT2 | fucosyltransferase 2 (secretor status included) |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GK2 | glycerol kinase 2 |
| GLRA2 | glycine receptor, alpha 2 |
| GPR15 | G protein-coupled receptor 15 |
| GPR173 | G protein-coupled receptor 173 |
| GPR3 | G protein-coupled receptor 3 |
| GRIP2 | glutamate receptor interacting protein 2 |
| GRPR | gastrin-releasing peptide receptor |
| HAP1 | huntingtin-associated protein 1 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IL15RA | interleukin 15 receptor, alpha |
| IL18RAP | interleukin 18 receptor accessory protein |
| IL1B | interleukin 1, beta |
| IL5RA | interleukin 5 receptor, alpha |
| IL7R | interleukin 7 receptor |
| INSL4 | insulin-like 4 (placenta) |
| KCNJ8 | potassium channel, inwardly rectifying subfamily J, member 8 |
| KIR3DS1 | killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1 |
| KLHL28 | kelch-like family member 28 |
| KRTAP1-1 | keratin associated protein 1-1 |
| LHX2 | LIM homeobox 2 |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) |
| LMTK2 | lemur tyrosine kinase 2 |
| LOC441601 | septin 7 pseudogene |
| LRP4 | low density lipoprotein receptor-related protein 4 |
| LRP6 | low density lipoprotein receptor-related protein 6 |
| LTK | leukocyte receptor tyrosine kinase |
| LUZP4 | leucine zipper protein 4 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAS1 | MAS1 proto-oncogene, G protein-coupled receptor |
| MC5R | melanocortin 5 receptor |
| MFNG | MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow |
| NDRG2 | NDRG family member 2 |
| NOX5 | NADPH oxidase, EF-hand calcium binding domain 5 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| PCYT1B | phosphate cytidylyltransferase 1, choline, beta |
| PHOX2A | paired-like homeobox 2a |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RARG | retinoic acid receptor, gamma |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RBMXL2 | RNA binding motif protein, X-linked-like 2 |
| SLAMF8 | SLAM family member 8 |
| SLC22A17 | solute carrier family 22, member 17 |
| SLC45A2 | solute carrier family 45, member 2 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SMAD3 | SMAD family member 3 |
| SYT2 | synaptotagmin II |
| TCP11 | t-complex 11, testis-specific |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TNFSF8 | tumor necrosis factor (ligand) superfamily, member 8 |
| TP53TG5 | TP53 target 5 |
| TRAC | T cell receptor alpha constant |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| TTC22 | tetratricopeptide repeat domain 22 |
| TYMP | thymidine phosphorylase |
| USF2 | upstream transcription factor 2, c-fos interacting |
| USP29 | ubiquitin specific peptidase 29 |
| USP46 | ubiquitin specific peptidase 46 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked |
| VARS | valyl-tRNA synthetase |
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| AES | amino-terminal enhancer of split |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ARMC7 | armadillo repeat containing 7 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| CARS2 | cysteinyl-tRNA synthetase 2, mitochondrial (putative) |
| CBX7 | chromobox homolog 7 |
| CCDC130 | coiled-coil domain containing 130 |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CEP72 | centrosomal protein 72kDa |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| CLDN17 | claudin 17 |
| CLPB | ClpB homolog, mitochondrial AAA ATPase chaperonin |
| CLSTN2 | calsyntenin 2 |
| CROT | carnitine O-octanoyltransferase |
| CRY1 | cryptochrome circadian clock 1 |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CUEDC1 | CUE domain containing 1 |
| CYB5R2 | cytochrome b5 reductase 2 |
| DGKD | diacylglycerol kinase, delta 130kDa |
| ECE2 | endothelin converting enzyme 2 |
| EFNA3 | ephrin-A3 |
| EXOC5 | exocyst complex component 5 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FANCF | Fanconi anemia, complementation group F |
| FCGR1B | Fc fragment of IgG, high affinity Ib, receptor (CD64) |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| FXN | frataxin |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GALR3 | galanin receptor 3 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HMHA1 | histocompatibility (minor) HA-1 |
| IL4R | interleukin 4 receptor |
| ITPKB | inositol-trisphosphate 3-kinase B |
| JOSD1 | Josephin domain containing 1 |
| KBTBD4 | kelch repeat and BTB (POZ) domain containing 4 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIF20B | kinesin family member 20B |
| KIR2DL3 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 |
| KLHL2 | kelch-like family member 2 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LINC00574 | long intergenic non-protein coding RNA 574 |
| LTBP3 | latent transforming growth factor beta binding protein 3 |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| METTL8 | methyltransferase like 8 |
| MGA | MGA, MAX dimerization protein |
| MON1B | MON1 secretory trafficking family member B |
| MORC3 | MORC family CW-type zinc finger 3 |
| MRPL12 | mitochondrial ribosomal protein L12 |
| MXD3 | MAX dimerization protein 3 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| OR7A17 | olfactory receptor, family 7, subfamily A, member 17 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| P3H4 | prolyl 3-hydroxylase family member 4 (non-enzymatic) |
| PCDHB3 | protocadherin beta 3 |
| PCTP | phosphatidylcholine transfer protein |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PFAS | phosphoribosylformylglycinamidine synthase |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PLCD1 | phospholipase C, delta 1 |
| RAD54L | RAD54-like (S. cerevisiae) |
| RAI14 | retinoic acid induced 14 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain |
| RGP1 | RGP1 retrograde golgi transport homolog (S. cerevisiae) |
| RGS17 | regulator of G-protein signaling 17 |
| RHOH | ras homolog family member H |
| RNF185 | ring finger protein 185 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC50A1 | solute carrier family 50 (sugar efflux transporter), member 1 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SMCO4 | single-pass membrane protein with coiled-coil domains 4 |
| SPEG | SPEG complex locus |
| T | T, brachyury homolog (mouse) |
| TCEA2 | transcription elongation factor A (SII), 2 |
| TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 |
| THOC6 | THO complex 6 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) |
| TJP2 | tight junction protein 2 |
| TOE1 | target of EGR1, member 1 (nuclear) |
| TTC1 | tetratricopeptide repeat domain 1 |
| TTC4 | tetratricopeptide repeat domain 4 |
| TTR | transthyretin |
| TUBGCP3 | tubulin, gamma complex associated protein 3 |
| WDR18 | WD repeat domain 18 |
| WDR46 | WD repeat domain 46 |
| WDR91 | WD repeat domain 91 |
| WT1-AS | WT1 antisense RNA |
| WWC2 | WW and C2 domain containing 2 |
| ZFP36 | ZFP36 ring finger protein |
