| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the sirolimus-4431 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ACTC1 | actin, alpha, cardiac muscle 1 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CD52 | CD52 molecule |
| CD6 | CD6 molecule |
| CEP162 | centrosomal protein 162kDa |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CNPY4 | canopy FGF signaling regulator 4 |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CTSZ | cathepsin Z |
| CXORF21 | chromosome X open reading frame 21 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| DHRS12 | dehydrogenase/reductase (SDR family) member 12 |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| DPY19L1 | dpy-19-like 1 (C. elegans) |
| DST | dystonin |
| EFNA5 | ephrin-A5 |
| EGFR | epidermal growth factor receptor |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) |
| ERC2-IT1 | ERC2 intronic transcript 1 |
| ETV1 | ets variant 1 |
| EVX1 | even-skipped homeobox 1 |
| FLOT1 | flotillin 1 |
| FOXO4 | forkhead box O4 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GPLD1 | glycosylphosphatidylinositol specific phospholipase D1 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
| GYPC | glycophorin C (Gerbich blood group) |
| HBP1 | HMG-box transcription factor 1 |
| HEG1 | heart development protein with EGF-like domains 1 |
| HEMK1 | HemK methyltransferase family member 1 |
| HFE | hemochromatosis |
| ICOS | inducible T-cell co-stimulator |
| IGF1R | insulin-like growth factor 1 receptor |
| IRF4 | interferon regulatory factor 4 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| ITGB7 | integrin, beta 7 |
| KCNB1 | potassium channel, voltage gated Shab related subfamily B, member 1 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 |
| KLF1 | Kruppel-like factor 1 (erythroid) |
| KLHL24 | kelch-like family member 24 |
| LAMA4 | laminin, alpha 4 |
| LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| LOC79999 | uncharacterized LOC79999 |
| LPL | lipoprotein lipase |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LTC4S | leukotriene C4 synthase |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 |
| MCF2L | MCF.2 cell line derived transforming sequence-like |
| MIA | melanoma inhibitory activity |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NCOR2 | nuclear receptor corepressor 2 |
| NIPAL2 | NIPA-like domain containing 2 |
| NNMT | nicotinamide N-methyltransferase |
| NPAS3 | neuronal PAS domain protein 3 |
| PALM | paralemmin |
| PART1 | prostate androgen-regulated transcript 1 (non-protein coding) |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited |
| PIGR | polymeric immunoglobulin receptor |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PRB4 | proline-rich protein BstNI subfamily 4 |
| PRY | PTPN13-like, Y-linked |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| PTPRR | protein tyrosine phosphatase, receptor type, R |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| RND1 | Rho family GTPase 1 |
| RPLP2 | ribosomal protein, large, P2 |
| SCN11A | sodium channel, voltage gated, type XI alpha subunit |
| SCN8A | sodium channel, voltage gated, type VIII alpha subunit |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 |
| SLC44A4 | solute carrier family 44, member 4 |
| SLC52A1 | solute carrier family 52 (riboflavin transporter), member 1 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 |
| STAT2 | signal transducer and activator of transcription 2, 113kDa |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 |
| TNPO2 | transportin 2 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TPM1 | tropomyosin 1 (alpha) |
| TRD | T cell receptor delta locus |
| TSPAN9 | tetraspanin 9 |
| TXK | TXK tyrosine kinase |
| WSB1 | WD repeat and SOCS box containing 1 |
| ZBTB20 | zinc finger and BTB domain containing 20 |
| ZCCHC14 | zinc finger, CCHC domain containing 14 |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| Symbol | Name |
|---|---|
| ABCA11P | ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARL4A | ADP-ribosylation factor-like 4A |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BTC | betacellulin |
| BYSL | bystin-like |
| C12ORF43 | chromosome 12 open reading frame 43 |
| C1ORF109 | chromosome 1 open reading frame 109 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CAPN15 | calpain 15 |
| CCNJ | cyclin J |
| CCNJL | cyclin J-like |
| CCP110 | centriolar coiled coil protein 110kDa |
| CENPB | centromere protein B, 80kDa |
| CHN1 | chimerin 1 |
| COBL | cordon-bleu WH2 repeat protein |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| DBF4B | DBF4 zinc finger B |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DNAJC13 | DnaJ (Hsp40) homolog, subfamily C, member 13 |
| ECM1 | extracellular matrix protein 1 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 |
| GPR87 | G protein-coupled receptor 87 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HAS2 | hyaluronan synthase 2 |
| HIST1H2BJ | histone cluster 1, H2bj |
| HIST1H4C | histone cluster 1, H4c |
| HIST1H4E | histone cluster 1, H4e |
| HOMER2 | homer scaffolding protein 2 |
| HOXC10 | homeobox C10 |
| HOXC5 | homeobox C5 |
| IFRD1 | interferon-related developmental regulator 1 |
| JMJD4 | jumonji domain containing 4 |
| KCTD5 | potassium channel tetramerization domain containing 5 |
| KIAA0020 | KIAA0020 |
| LETM1 | leucine zipper-EF-hand containing transmembrane protein 1 |
| LIPG | lipase, endothelial |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LYPD3 | LY6/PLAUR domain containing 3 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| MNS1 | meiosis-specific nuclear structural 1 |
| MTA2 | metastasis associated 1 family, member 2 |
| MTCL1 | microtubule crosslinking factor 1 |
| MYLIP | myosin regulatory light chain interacting protein |
| NDUFAF4 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 |
| NOC4L | nucleolar complex associated 4 homolog (S. cerevisiae) |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NOP2 | NOP2 nucleolar protein |
| NXT1 | nuclear transport factor 2-like export factor 1 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PC | pyruvate carboxylase |
| PDSS1 | prenyl (decaprenyl) diphosphate synthase, subunit 1 |
| PDSS2 | prenyl (decaprenyl) diphosphate synthase, subunit 2 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLXNA3 | plexin A3 |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| PTGFR | prostaglandin F receptor (FP) |
| PTX3 | pentraxin 3, long |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SELL | selectin L |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SIAH2 | siah E3 ubiquitin protein ligase 2 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SNHG3 | small nucleolar RNA host gene 3 |
| SOWAHC | sosondowah ankyrin repeat domain family member C |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| THOP1 | thimet oligopeptidase 1 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TIPIN | TIMELESS interacting protein |
| TRIM16 | tripartite motif containing 16 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TUBA3C | tubulin, alpha 3c |
| TUBA3D | tubulin, alpha 3d |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| USB1 | U6 snRNA biogenesis 1 |
| VWA1 | von Willebrand factor A domain containing 1 |
| WDR3 | WD repeat domain 3 |
| WDR43 | WD repeat domain 43 |
| WDR46 | WD repeat domain 46 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZNF141 | zinc finger protein 141 |
| ZNF197 | zinc finger protein 197 |
| ZNF215 | zinc finger protein 215 |
| ZNF329 | zinc finger protein 329 |
| ZNF747 | zinc finger protein 747 |
