| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the sirolimus-4445 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACSS3 | acyl-CoA synthetase short-chain family member 3 |
| AMACR | alpha-methylacyl-CoA racemase |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 |
| APOE | apolipoprotein E |
| ARL14 | ADP-ribosylation factor-like 14 |
| ATM | ATM serine/threonine kinase |
| ATN1 | atrophin 1 |
| ATP9A | ATPase, class II, type 9A |
| ATXN7L1 | ataxin 7-like 1 |
| BCAM | basal cell adhesion molecule (Lutheran blood group) |
| C10ORF10 | chromosome 10 open reading frame 10 |
| CADM3 | cell adhesion molecule 3 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CCDC132 | coiled-coil domain containing 132 |
| CCNG2 | cyclin G2 |
| CDKN2B | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CLIC5 | chloride intracellular channel 5 |
| CPN2 | carboxypeptidase N, polypeptide 2 |
| CSF1 | colony stimulating factor 1 (macrophage) |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| EDN1 | endothelin 1 |
| EFCAB6 | EF-hand calcium binding domain 6 |
| ETV1 | ets variant 1 |
| FAM135A | family with sequence similarity 135, member A |
| FAS | Fas cell surface death receptor |
| FGF6 | fibroblast growth factor 6 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GAS7 | growth arrest-specific 7 |
| GPR19 | G protein-coupled receptor 19 |
| GYG2 | glycogenin 2 |
| HBP1 | HMG-box transcription factor 1 |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| IGF1R | insulin-like growth factor 1 receptor |
| IRF4 | interferon regulatory factor 4 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| KCNB1 | potassium channel, voltage gated Shab related subfamily B, member 1 |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 |
| KIAA1456 | KIAA1456 |
| KIF1A | kinesin family member 1A |
| KLF13 | Kruppel-like factor 13 |
| KLHL24 | kelch-like family member 24 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| LAMA4 | laminin, alpha 4 |
| LOX | lysyl oxidase |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MAP2K7 | mitogen-activated protein kinase kinase 7 |
| MAP7D3 | MAP7 domain containing 3 |
| MED16 | mediator complex subunit 16 |
| MSL3 | male-specific lethal 3 homolog (Drosophila) |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NDUFA2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NF1 | neurofibromin 1 |
| NNMT | nicotinamide N-methyltransferase |
| NPAS3 | neuronal PAS domain protein 3 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NR1H4 | nuclear receptor subfamily 1, group H, member 4 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OSBPL7 | oxysterol binding protein-like 7 |
| PADI3 | peptidyl arginine deiminase, type III |
| PCDH12 | protocadherin 12 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| PRUNE2 | prune homolog 2 (Drosophila) |
| PVRL1 | poliovirus receptor-related 1 (herpesvirus entry mediator C) |
| RAB36 | RAB36, member RAS oncogene family |
| RNFT1 | ring finger protein, transmembrane 1 |
| SCN11A | sodium channel, voltage gated, type XI alpha subunit |
| SEMA4F | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F |
| SFRP4 | secreted frizzled-related protein 4 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SMAD1 | SMAD family member 1 |
| SYT12 | synaptotagmin XII |
| SZT2 | seizure threshold 2 homolog (mouse) |
| TFEB | transcription factor EB |
| THSD4 | thrombospondin, type I, domain containing 4 |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 |
| TMPRSS2 | transmembrane protease, serine 2 |
| TRPV4 | transient receptor potential cation channel, subfamily V, member 4 |
| TSPAN7 | tetraspanin 7 |
| TTC30A | tetratricopeptide repeat domain 30A |
| VEZT | vezatin, adherens junctions transmembrane protein |
| WSB1 | WD repeat and SOCS box containing 1 |
| ZIC3 | Zic family member 3 |
| ZIM2 | zinc finger, imprinted 2 |
| ZNF516 | zinc finger protein 516 |
| Symbol | Name |
|---|---|
| AGMAT | agmatine ureohydrolase (agmatinase) |
| AOC2 | amine oxidase, copper containing 2 (retina-specific) |
| ARPC5L | actin related protein 2/3 complex, subunit 5-like |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
| C3 | complement component 3 |
| CA11 | carbonic anhydrase XI |
| CCDC85C | coiled-coil domain containing 85C |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CD82 | CD82 molecule |
| CENPO | centromere protein O |
| CISH | cytokine inducible SH2-containing protein |
| CORO1A | coronin, actin binding protein, 1A |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DDN | dendrin |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DENND2D | DENN/MADD domain containing 2D |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DUSP9 | dual specificity phosphatase 9 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EFNA3 | ephrin-A3 |
| EFNB1 | ephrin-B1 |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FBXO31 | F-box protein 31 |
| FGFBP1 | fibroblast growth factor binding protein 1 |
| FRMD1 | FERM domain containing 1 |
| GLB1L2 | galactosidase, beta 1-like 2 |
| HIST1H4C | histone cluster 1, H4c |
| HOXC13 | homeobox C13 |
| HYMAI | hydatidiform mole associated and imprinted (non-protein coding) |
| IFNA14 | interferon, alpha 14 |
| IL17RB | interleukin 17 receptor B |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ITPKA | inositol-trisphosphate 3-kinase A |
| KLK7 | kallikrein-related peptidase 7 |
| LAMC3 | laminin, gamma 3 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| MAP6D1 | MAP6 domain containing 1 |
| MDFI | MyoD family inhibitor |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MMP2 | matrix metallopeptidase 2 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MTA2 | metastasis associated 1 family, member 2 |
| NCALD | neurocalcin delta |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NID2 | nidogen 2 (osteonidogen) |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| NUFIP1 | nuclear fragile X mental retardation protein interacting protein 1 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PAM16 | presequence translocase-associated motor 16 homolog (S. cerevisiae) |
| PDSS1 | prenyl (decaprenyl) diphosphate synthase, subunit 1 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PITX1 | paired-like homeodomain 1 |
| PLSCR2 | phospholipid scramblase 2 |
| PLXNB3 | plexin B3 |
| PMM2 | phosphomannomutase 2 |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa |
| PPAT | phosphoribosyl pyrophosphate amidotransferase |
| PPM1G | protein phosphatase, Mg2+/Mn2+ dependent, 1G |
| PTPRH | protein tyrosine phosphatase, receptor type, H |
| PUS1 | pseudouridylate synthase 1 |
| PXMP4 | peroxisomal membrane protein 4, 24kDa |
| RNF122 | ring finger protein 122 |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SOSTDC1 | sclerostin domain containing 1 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| STRN | striatin, calmodulin binding protein |
| SYT17 | synaptotagmin XVII |
| TCEAL2 | transcription elongation factor A (SII)-like 2 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) |
| TIPIN | TIMELESS interacting protein |
| TMEM206 | transmembrane protein 206 |
| TOMM40 | translocase of outer mitochondrial membrane 40 homolog (yeast) |
| TTLL12 | tubulin tyrosine ligase-like family member 12 |
| UNC119 | unc-119 homolog (C. elegans) |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| VGF | VGF nerve growth factor inducible |
| WDR4 | WD repeat domain 4 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZNF124 | zinc finger protein 124 |
| ZNF222 | zinc finger protein 222 |
| ZNF639 | zinc finger protein 639 |
| ZNF747 | zinc finger protein 747 |
| ZNF787 | zinc finger protein 787 |
| ZNF816 | zinc finger protein 816 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
