| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the sirolimus-4466 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ABCC9 | ATP-binding cassette, sub-family C (CFTR/MRP), member 9 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein |
| ALOXE3 | arachidonate lipoxygenase 3 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| APAF1 | apoptotic peptidase activating factor 1 |
| ARL14 | ADP-ribosylation factor-like 14 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| CACFD1 | calcium channel flower domain containing 1 |
| CAMSAP1 | calmodulin regulated spectrin-associated protein 1 |
| CCNG2 | cyclin G2 |
| CCPG1 | cell cycle progression 1 |
| CDK20 | cyclin-dependent kinase 20 |
| CDKN2B | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CIC | capicua transcriptional repressor |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CTSZ | cathepsin Z |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DENND3 | DENN/MADD domain containing 3 |
| DNAJC16 | DnaJ (Hsp40) homolog, subfamily C, member 16 |
| ERC2-IT1 | ERC2 intronic transcript 1 |
| FLT1 | fms-related tyrosine kinase 1 |
| FN1 | fibronectin 1 |
| GGT1 | gamma-glutamyltransferase 1 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide |
| GPR182 | G protein-coupled receptor 182 |
| HBP1 | HMG-box transcription factor 1 |
| HSF2BP | heat shock transcription factor 2 binding protein |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IL22RA1 | interleukin 22 receptor, alpha 1 |
| IL33 | interleukin 33 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| ITGB4 | integrin, beta 4 |
| KIR2DL1 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 |
| KLF13 | Kruppel-like factor 13 |
| KLHL24 | kelch-like family member 24 |
| KSR1 | kinase suppressor of ras 1 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 |
| LRP1 | low density lipoprotein receptor-related protein 1 |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| MAGEA5 | melanoma antigen family A5 |
| MEGF6 | multiple EGF-like-domains 6 |
| MMP7 | matrix metallopeptidase 7 |
| MORN1 | MORN repeat containing 1 |
| MST1L | macrophage stimulating 1-like |
| MTMR8 | myotubularin related protein 8 |
| NFIB | nuclear factor I/B |
| NNMT | nicotinamide N-methyltransferase |
| NPHS2 | nephrosis 2, idiopathic, steroid-resistant (podocin) |
| OR2S2 | olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene) |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDE5A | phosphodiesterase 5A, cGMP-specific |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PRDM9 | PR domain containing 9 |
| PSMD5 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RNASE4 | ribonuclease, RNase A family, 4 |
| RND1 | Rho family GTPase 1 |
| RNF208 | ring finger protein 208 |
| RPL7 | ribosomal protein L7 |
| RUNX1 | runt-related transcription factor 1 |
| SDC3 | syndecan 3 |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) |
| SH3GL3 | SH3-domain GRB2-like 3 |
| SNN | stannin |
| SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 |
| STON1 | stonin 1 |
| SZT2 | seizure threshold 2 homolog (mouse) |
| TBL1Y | transducin (beta)-like 1, Y-linked |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TEF | thyrotrophic embryonic factor |
| TENM1 | teneurin transmembrane protein 1 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TFR2 | transferrin receptor 2 |
| THRA | thyroid hormone receptor, alpha |
| TMPRSS3 | transmembrane protease, serine 3 |
| TNFSF15 | tumor necrosis factor (ligand) superfamily, member 15 |
| TOM1L2 | target of myb1-like 2 (chicken) |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TRIM29 | tripartite motif containing 29 |
| ULK1 | unc-51 like autophagy activating kinase 1 |
| VPS9D1 | VPS9 domain containing 1 |
| VWA5A | von Willebrand factor A domain containing 5A |
| WDR48 | WD repeat domain 48 |
| WSB1 | WD repeat and SOCS box containing 1 |
| ZBTB20 | zinc finger and BTB domain containing 20 |
| ZNF154 | zinc finger protein 154 |
| ZNF518A | zinc finger protein 518A |
| ZNF771 | zinc finger protein 771 |
| Symbol | Name |
|---|---|
| ADAM23 | ADAM metallopeptidase domain 23 |
| ARMCX2 | armadillo repeat containing, X-linked 2 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| AURKC | aurora kinase C |
| BBC3 | BCL2 binding component 3 |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
| BMPR1B | bone morphogenetic protein receptor, type IB |
| BRIX1 | BRX1, biogenesis of ribosomes |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CCDC121 | coiled-coil domain containing 121 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CEP295 | centrosomal protein 295kDa |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CYB5R2 | cytochrome b5 reductase 2 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDN | dendrin |
| DEPDC5 | DEP domain containing 5 |
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FGFBP1 | fibroblast growth factor binding protein 1 |
| FKBP5 | FK506 binding protein 5 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GRTP1 | growth hormone regulated TBC protein 1 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2BN | histone cluster 1, H2bn |
| HIST1H3A | histone cluster 1, H3a |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HOXB2 | homeobox B2 |
| HSPA1L | heat shock 70kDa protein 1-like |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| KIAA0020 | KIAA0020 |
| KIAA0513 | KIAA0513 |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| KLHL28 | kelch-like family member 28 |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| KRT32 | keratin 32, type I |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LIN7B | lin-7 homolog B (C. elegans) |
| LINS | lines homolog (Drosophila) |
| METTL16 | methyltransferase like 16 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase |
| MTA2 | metastasis associated 1 family, member 2 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NRTN | neurturin |
| NXT1 | nuclear transport factor 2-like export factor 1 |
| OSMR | oncostatin M receptor |
| PAX9 | paired box 9 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 |
| PGP | phosphoglycolate phosphatase |
| PITX2 | paired-like homeodomain 2 |
| PPAN | peter pan homolog (Drosophila) |
| PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PRR14L | proline rich 14-like |
| PTX3 | pentraxin 3, long |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RNF122 | ring finger protein 122 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPGRIP1L | RPGRIP1-like |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| RUNDC3B | RUN domain containing 3B |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| SLC35F6 | solute carrier family 35, member F6 |
| STAC | SH3 and cysteine rich domain |
| TCEAL2 | transcription elongation factor A (SII)-like 2 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 |
| TIPIN | TIMELESS interacting protein |
| TMEM206 | transmembrane protein 206 |
| TRIM9 | tripartite motif containing 9 |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| UTP20 | UTP20, small subunit (SSU) processome component, homolog (yeast) |
| VASH1 | vasohibin 1 |
| YARS | tyrosyl-tRNA synthetase |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZBTB33 | zinc finger and BTB domain containing 33 |
| ZNF276 | zinc finger protein 276 |
| ZNF280B | zinc finger protein 280B |
| ZNF41 | zinc finger protein 41 |
| ZNF639 | zinc finger protein 639 |
| ZNF675 | zinc finger protein 675 |
| ZNF711 | zinc finger protein 711 |
