| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the sirolimus-5204 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACPP | acid phosphatase, prostate |
| ADCK3 | aarF domain containing kinase 3 |
| AHCYL2 | adenosylhomocysteinase-like 2 |
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 |
| ALOXE3 | arachidonate lipoxygenase 3 |
| AMH | anti-Mullerian hormone |
| AMT | aminomethyltransferase |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 |
| APOM | apolipoprotein M |
| ARTN | artemin |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like |
| BST2 | bone marrow stromal cell antigen 2 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CAPN9 | calpain 9 |
| CBX7 | chromobox homolog 7 |
| CCNG2 | cyclin G2 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CNPPD1 | cyclin Pas1/PHO80 domain containing 1 |
| COL1A1 | collagen, type I, alpha 1 |
| CTBS | chitobiase, di-N-acetyl- |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| EFCAB2 | EF-hand calcium binding domain 2 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| EZH1 | enhancer of zeste 1 polycomb repressive complex 2 subunit |
| FCN2 | ficolin (collagen/fibrinogen domain containing lectin) 2 |
| FHIT | fragile histidine triad |
| FLJ22184 | |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GFI1 | growth factor independent 1 transcription repressor |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GM2A | GM2 ganglioside activator |
| GPER1 | G protein-coupled estrogen receptor 1 |
| GPR143 | G protein-coupled receptor 143 |
| HAMP | hepcidin antimicrobial peptide |
| HEG1 | heart development protein with EGF-like domains 1 |
| HR | hair growth associated |
| HSPB11 | heat shock protein family B (small), member 11 |
| IFT27 | intraflagellar transport 27 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| ING4 | inhibitor of growth family, member 4 |
| IRS2 | insulin receptor substrate 2 |
| ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) |
| KIAA1456 | KIAA1456 |
| KLHL24 | kelch-like family member 24 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| METTL7A | methyltransferase like 7A |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MPPE1 | metallophosphoesterase 1 |
| MTCP1 | mature T-cell proliferation 1 |
| MXD4 | MAX dimerization protein 4 |
| MZF1 | myeloid zinc finger 1 |
| N4BP3 | NEDD4 binding protein 3 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NELL2 | NEL-like 2 (chicken) |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PIN4 | peptidylprolyl cis/trans isomerase, NIMA-interacting 4 |
| PLK3 | polo-like kinase 3 |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAD52 | RAD52 homolog (S. cerevisiae) |
| RALGDS | ral guanine nucleotide dissociation stimulator |
| RBL2 | retinoblastoma-like 2 |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 |
| SDC3 | syndecan 3 |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 |
| SLC35E2 | solute carrier family 35, member E2 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SMIM14 | small integral membrane protein 14 |
| SNX13 | sorting nexin 13 |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| SRCAP | Snf2-related CREBBP activator protein |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| TACC1 | transforming, acidic coiled-coil containing protein 1 |
| TECTA | tectorin alpha |
| TMCO6 | transmembrane and coiled-coil domains 6 |
| TRAK1 | trafficking protein, kinesin binding 1 |
| TTC9 | tetratricopeptide repeat domain 9 |
| TUBA4B | tubulin, alpha 4b |
| TXNIP | thioredoxin interacting protein |
| ULK2 | unc-51 like autophagy activating kinase 2 |
| UROD | uroporphyrinogen decarboxylase |
| VPS9D1 | VPS9 domain containing 1 |
| YY2 | YY2 transcription factor |
| ZNF350 | zinc finger protein 350 |
| ZNF532 | zinc finger protein 532 |
| ZNF862 | zinc finger protein 862 |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| AFF4 | AF4/FMR2 family, member 4 |
| AKIRIN1 | akirin 1 |
| ARMC6 | armadillo repeat containing 6 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa |
| BYSL | bystin-like |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CBX8 | chromobox homolog 8 |
| CCDC86 | coiled-coil domain containing 86 |
| CCDC88C | coiled-coil domain containing 88C |
| CCNO | cyclin O |
| CDR2 | cerebellar degeneration-related protein 2, 62kDa |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHMP6 | charged multivesicular body protein 6 |
| CHMP7 | charged multivesicular body protein 7 |
| CORO1A | coronin, actin binding protein, 1A |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DCP1A | decapping mRNA 1A |
| DCUN1D2 | DCN1, defective in cullin neddylation 1, domain containing 2 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 |
| DUSP8 | dual specificity phosphatase 8 |
| DVL1 | dishevelled segment polarity protein 1 |
| EAF2 | ELL associated factor 2 |
| ERCC5 | excision repair cross-complementation group 5 |
| FAAH | fatty acid amide hydrolase |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FOSL1 | FOS-like antigen 1 |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GALE | UDP-galactose-4-epimerase |
| GALK1 | galactokinase 1 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HCFC2 | host cell factor C2 |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| IFRD1 | interferon-related developmental regulator 1 |
| IL22 | interleukin 22 |
| INPPL1 | inositol polyphosphate phosphatase-like 1 |
| IRF9 | interferon regulatory factor 9 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| METTL16 | methyltransferase like 16 |
| MLYCD | malonyl-CoA decarboxylase |
| MRPL52 | mitochondrial ribosomal protein L52 |
| MSX1 | msh homeobox 1 |
| MUC3A | mucin 3A, cell surface associated |
| NARFL | nuclear prelamin A recognition factor-like |
| NCS1 | neuronal calcium sensor 1 |
| NOL12 | nucleolar protein 12 |
| NRSN2 | neurensin 2 |
| NSD1 | nuclear receptor binding SET domain protein 1 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PCDHA6 | protocadherin alpha 6 |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PRR14L | proline rich 14-like |
| PRR4 | proline rich 4 (lacrimal) |
| PTDSS2 | phosphatidylserine synthase 2 |
| RAI14 | retinoic acid induced 14 |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RGS16 | regulator of G-protein signaling 16 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RNF43 | ring finger protein 43 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| SURF2 | surfeit 2 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TMEM39B | transmembrane protein 39B |
| TMEM53 | transmembrane protein 53 |
| TNS2 | tensin 2 |
| TRABD | TraB domain containing |
| TRIM25 | tripartite motif containing 25 |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TRNAU1AP | tRNA selenocysteine 1 associated protein 1 |
| TWISTNB | TWIST neighbor |
| UNC119 | unc-119 homolog (C. elegans) |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| VGF | VGF nerve growth factor inducible |
| WDR4 | WD repeat domain 4 |
| WDR43 | WD repeat domain 43 |
| YEATS2 | YEATS domain containing 2 |
| YRDC | yrdC N(6)-threonylcarbamoyltransferase domain containing |
| ZNF205 | zinc finger protein 205 |
| ZNF446 | zinc finger protein 446 |
| ZNF696 | zinc finger protein 696 |