| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the sirolimus-5218 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AGRP | agouti related neuropeptide |
| ALK | anaplastic lymphoma receptor tyrosine kinase |
| ALPPL2 | alkaline phosphatase, placental-like 2 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| ARMC4 | armadillo repeat containing 4 |
| ARTN | artemin |
| ASPH | aspartate beta-hydroxylase |
| ATF7IP | activating transcription factor 7 interacting protein |
| ATP6V0A4 | ATPase, H+ transporting, lysosomal V0 subunit a4 |
| BBC3 | BCL2 binding component 3 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CD36 | CD36 molecule (thrombospondin receptor) |
| COMT | catechol-O-methyltransferase |
| CROCC | ciliary rootlet coiled-coil, rootletin |
| CTNS | cystinosin, lysosomal cystine transporter |
| CUL7 | cullin 7 |
| DEPDC5 | DEP domain containing 5 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog |
| FBXO2 | F-box protein 2 |
| FGF12 | fibroblast growth factor 12 |
| FLJ22184 | |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GLB1L | galactosidase, beta 1-like |
| GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 |
| GPNMB | glycoprotein (transmembrane) nmb |
| GPR143 | G protein-coupled receptor 143 |
| GRB7 | growth factor receptor-bound protein 7 |
| GREB1 | growth regulation by estrogen in breast cancer 1 |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| HAMP | hepcidin antimicrobial peptide |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HTR1F | 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled |
| HYAL3 | hyaluronoglucosaminidase 3 |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IFNA14 | interferon, alpha 14 |
| IGHA1 | immunoglobulin heavy constant alpha 1 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 |
| KIAA0319L | KIAA0319-like |
| KLHL24 | kelch-like family member 24 |
| KRT15 | keratin 15, type I |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MAP4 | microtubule-associated protein 4 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MFAP2 | microfibrillar-associated protein 2 |
| MSL3 | male-specific lethal 3 homolog (Drosophila) |
| NAG18 | NAG18 mRNA |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NOL10 | nucleolar protein 10 |
| NOVA2 | neuro-oncological ventral antigen 2 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| NSUN6 | NOP2/Sun domain family, member 6 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCDHGA8 | protocadherin gamma subfamily A, 8 |
| PDE4C | phosphodiesterase 4C, cAMP-specific |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PLCD1 | phospholipase C, delta 1 |
| PLLP | plasmolipin |
| POU2F2 | POU class 2 homeobox 2 |
| PSG9 | pregnancy specific beta-1-glycoprotein 9 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| PTK6 | protein tyrosine kinase 6 |
| RAB6B | RAB6B, member RAS oncogene family |
| RHBDD3 | rhomboid domain containing 3 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 |
| S100A7 | S100 calcium binding protein A7 |
| S100A9 | S100 calcium binding protein A9 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SPAG4 | sperm associated antigen 4 |
| SPAG8 | sperm associated antigen 8 |
| SPN | sialophorin |
| STAB2 | stabilin 2 |
| TAOK1 | TAO kinase 1 |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TIGD6 | tigger transposable element derived 6 |
| TP63 | tumor protein p63 |
| TRIM21 | tripartite motif containing 21 |
| TSPAN31 | tetraspanin 31 |
| TTC23 | tetratricopeptide repeat domain 23 |
| TXNIP | thioredoxin interacting protein |
| UCN | urocortin |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZNF862 | zinc finger protein 862 |
| ZSCAN2 | zinc finger and SCAN domain containing 2 |
| Symbol | Name |
|---|---|
| AGO1 | argonaute RISC catalytic component 1 |
| AKIRIN1 | akirin 1 |
| ALDOC | aldolase C, fructose-bisphosphate |
| ALPK1 | alpha-kinase 1 |
| ARSB | arylsulfatase B |
| ATG4A | autophagy related 4A, cysteine peptidase |
| AUNIP | aurora kinase A and ninein interacting protein |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CCDC86 | coiled-coil domain containing 86 |
| CCDC88C | coiled-coil domain containing 88C |
| CDC25A | cell division cycle 25A |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 |
| COA7 | cytochrome c oxidase assembly factor 7 (putative) |
| CORO1A | coronin, actin binding protein, 1A |
| CPTP | ceramide-1-phosphate transfer protein |
| CRYBG3 | beta-gamma crystallin domain containing 3 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CTPS1 | CTP synthase 1 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DEAF1 | DEAF1 transcription factor |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 |
| DUSP5 | dual specificity phosphatase 5 |
| DVL1 | dishevelled segment polarity protein 1 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| E2F8 | E2F transcription factor 8 |
| EIF5 | eukaryotic translation initiation factor 5 |
| ENO2 | enolase 2 (gamma, neuronal) |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM155B | family with sequence similarity 155, member B |
| FASTKD5 | FAST kinase domains 5 |
| FKBP14 | FK506 binding protein 14, 22 kDa |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| GALK1 | galactokinase 1 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GSTT1 | glutathione S-transferase theta 1 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IDH3A | isocitrate dehydrogenase 3 (NAD+) alpha |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFRD1 | interferon-related developmental regulator 1 |
| IP6K1 | inositol hexakisphosphate kinase 1 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| LYRM9 | LYR motif containing 9 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MAMLD1 | mastermind-like domain containing 1 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| METTL1 | methyltransferase like 1 |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MSL1 | male-specific lethal 1 homolog (Drosophila) |
| MTHFS | 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) |
| NXN | nucleoredoxin |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PCTP | phosphatidylcholine transfer protein |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| POGLUT1 | protein O-glucosyltransferase 1 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 |
| PRR3 | proline rich 3 |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RAI14 | retinoic acid induced 14 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RGS16 | regulator of G-protein signaling 16 |
| RNF25 | ring finger protein 25 |
| RNF31 | ring finger protein 31 |
| RPIA | ribose 5-phosphate isomerase A |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 |
| SPHK1 | sphingosine kinase 1 |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| SRRD | SRR1 domain containing |
| STEAP3 | STEAP family member 3, metalloreductase |
| STRN | striatin, calmodulin binding protein |
| SUSD4 | sushi domain containing 4 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TMEM180 | transmembrane protein 180 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TSLIG2 | tRNA splicing ligase complex subunit 2 |
| UBE2Q1 | ubiquitin-conjugating enzyme E2Q family member 1 |
| UBE2S | ubiquitin-conjugating enzyme E2S |
| UBQLN4 | ubiquilin 4 |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| WDR3 | WD repeat domain 3 |
| WDR4 | WD repeat domain 4 |
| WDR91 | WD repeat domain 91 |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZNF34 | zinc finger protein 34 |
| ZNF692 | zinc finger protein 692 |
