| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the sirolimus-5239 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AHNAK2 | AHNAK nucleoprotein 2 |
| AMPD1 | adenosine monophosphate deaminase 1 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| APC | adenomatous polyposis coli |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
| ASPH | aspartate beta-hydroxylase |
| ATP6V0A4 | ATPase, H+ transporting, lysosomal V0 subunit a4 |
| ATXN3 | ataxin 3 |
| BLNK | B-cell linker |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| CAPN9 | calpain 9 |
| CARF | calcium responsive transcription factor |
| CCNG2 | cyclin G2 |
| CCPG1 | cell cycle progression 1 |
| CDK19 | cyclin-dependent kinase 19 |
| CEP295 | centrosomal protein 295kDa |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CTH | cystathionine gamma-lyase |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DIXDC1 | DIX domain containing 1 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DUSP4 | dual specificity phosphatase 4 |
| EZH1 | enhancer of zeste 1 polycomb repressive complex 2 subunit |
| FAM105A | family with sequence similarity 105, member A |
| FCF1 | FCF1 rRNA-processing protein |
| FLJ21369 | uncharacterized protein FLJ21369 |
| GSPT1 | G1 to S phase transition 1 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HMGN5 | high mobility group nucleosome binding domain 5 |
| HMOX1 | heme oxygenase 1 |
| IFI6 | interferon, alpha-inducible protein 6 |
| ING4 | inhibitor of growth family, member 4 |
| KLHL22 | kelch-like family member 22 |
| KLHL24 | kelch-like family member 24 |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LEPR | leptin receptor |
| LRRC20 | leucine rich repeat containing 20 |
| LUZP4 | leucine zipper protein 4 |
| MADCAM1 | mucosal vascular addressin cell adhesion molecule 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MCOLN1 | mucolipin 1 |
| MSMB | microseminoprotein, beta- |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| PARD6B | par-6 family cell polarity regulator beta |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCDHA5 | protocadherin alpha 5 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLA2R1 | phospholipase A2 receptor 1, 180kDa |
| PLCD1 | phospholipase C, delta 1 |
| PLLP | plasmolipin |
| POLL | polymerase (DNA directed), lambda |
| PXN | paxillin |
| RAB3B | RAB3B, member RAS oncogene family |
| RB1CC1 | RB1-inducible coiled-coil 1 |
| RBBP9 | retinoblastoma binding protein 9 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RECQL5 | RecQ protein-like 5 |
| RIOK3 | RIO kinase 3 |
| RLN1 | relaxin 1 |
| RNMT | RNA (guanine-7-) methyltransferase |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 |
| RTN2 | reticulon 2 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor |
| SMIM14 | small integral membrane protein 14 |
| SORT1 | sortilin 1 |
| SP100 | SP100 nuclear antigen |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| SRCAP | Snf2-related CREBBP activator protein |
| SSPN | sarcospan |
| TBC1D22A | TBC1 domain family, member 22A |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TMEM254 | transmembrane protein 254 |
| TTC33 | tetratricopeptide repeat domain 33 |
| TXNIP | thioredoxin interacting protein |
| WDR48 | WD repeat domain 48 |
| WSB1 | WD repeat and SOCS box containing 1 |
| WWTR1 | WW domain containing transcription regulator 1 |
| ZBTB25 | zinc finger and BTB domain containing 25 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZMYND8 | zinc finger, MYND-type containing 8 |
| ZNF226 | zinc finger protein 226 |
| ZNF362 | zinc finger protein 362 |
| ZNF783 | zinc finger family member 783 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| ARPC5L | actin related protein 2/3 complex, subunit 5-like |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BMP4 | bone morphogenetic protein 4 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| CCDC86 | coiled-coil domain containing 86 |
| CDC25A | cell division cycle 25A |
| CDK3 | cyclin-dependent kinase 3 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CIC | capicua transcriptional repressor |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLDN15 | claudin 15 |
| CORO1A | coronin, actin binding protein, 1A |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CPTP | ceramide-1-phosphate transfer protein |
| CRLF1 | cytokine receptor-like factor 1 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DHDDS | dehydrodolichyl diphosphate synthase |
| ENO2 | enolase 2 (gamma, neuronal) |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| FAM53B | family with sequence similarity 53, member B |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 |
| GPR27 | G protein-coupled receptor 27 |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| HMHA1 | histocompatibility (minor) HA-1 |
| HOXA4 | homeobox A4 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IL22 | interleukin 22 |
| IL4R | interleukin 4 receptor |
| INPP1 | inositol polyphosphate-1-phosphatase |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| LAMP3 | lysosomal-associated membrane protein 3 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MMP3 | matrix metallopeptidase 3 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MTCL1 | microtubule crosslinking factor 1 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NRSN2 | neurensin 2 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PGBD5 | piggyBac transposable element derived 5 |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PNP | purine nucleoside phosphorylase |
| POLH | polymerase (DNA directed), eta |
| POM121 | POM121 transmembrane nucleoporin |
| POPDC3 | popeye domain containing 3 |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RAI14 | retinoic acid induced 14 |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RFPL1S | RFPL1 antisense RNA 1 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RGS16 | regulator of G-protein signaling 16 |
| RGS2 | regulator of G-protein signaling 2 |
| RNF43 | ring finger protein 43 |
| SECTM1 | secreted and transmembrane 1 |
| SETBP1 | SET binding protein 1 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SSBP3 | single stranded DNA binding protein 3 |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| STRN | striatin, calmodulin binding protein |
| TARS | threonyl-tRNA synthetase |
| TCTN2 | tectonic family member 2 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TMEM120B | transmembrane protein 120B |
| TMEM121 | transmembrane protein 121 |
| TMEM19 | transmembrane protein 19 |
| TMEM212 | transmembrane protein 212 |
| TPCN1 | two pore segment channel 1 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 |
| VPS11 | vacuolar protein sorting 11 homolog (S. cerevisiae) |
| WDR62 | WD repeat domain 62 |
| WFDC2 | WAP four-disulfide core domain 2 |
| YRDC | yrdC N(6)-threonylcarbamoyltransferase domain containing |
| ZNF41 | zinc finger protein 41 |
| ZNF428 | zinc finger protein 428 |
| ZNF639 | zinc finger protein 639 |
