| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the sirolimus-5567 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAK1 | AP2 associated kinase 1 |
| ACACB | acetyl-CoA carboxylase beta |
| ADAM12 | ADAM metallopeptidase domain 12 |
| ADCK3 | aarF domain containing kinase 3 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| APC | adenomatous polyposis coli |
| ARMC4 | armadillo repeat containing 4 |
| ATP6AP2 | ATPase, H+ transporting, lysosomal accessory protein 2 |
| BCL6 | B-cell CLL/lymphoma 6 |
| BIN1 | bridging integrator 1 |
| BLNK | B-cell linker |
| C14ORF79 | chromosome 14 open reading frame 79 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID |
| CARTPT | CART prepropeptide |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CCDC181 | coiled-coil domain containing 181 |
| CCDC70 | coiled-coil domain containing 70 |
| CCL23 | chemokine (C-C motif) ligand 23 |
| CCNG2 | cyclin G2 |
| CD300A | CD300a molecule |
| CENPO | centromere protein O |
| CIITA | class II, major histocompatibility complex, transactivator |
| CLDN1 | claudin 1 |
| CLUL1 | clusterin-like 1 (retinal) |
| CNTNAP2 | contactin associated protein-like 2 |
| CYHR1 | cysteine/histidine-rich 1 |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| EHD2 | EH-domain containing 2 |
| ELAVL2 | ELAV like neuron-specific RNA binding protein 2 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| EXOSC1 | exosome component 1 |
| EXT1 | exostosin glycosyltransferase 1 |
| FAXDC2 | fatty acid hydroxylase domain containing 2 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide |
| FCMR | Fc fragment of IgM receptor |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GNAS | GNAS complex locus |
| GPR143 | G protein-coupled receptor 143 |
| HAP1 | huntingtin-associated protein 1 |
| HCN2 | hyperpolarization activated cyclic nucleotide gated potassium channel 2 |
| HEG1 | heart development protein with EGF-like domains 1 |
| HHAT | hedgehog acyltransferase |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HLA-G | major histocompatibility complex, class I, G |
| HOXA7 | homeobox A7 |
| ING4 | inhibitor of growth family, member 4 |
| IQCK | IQ motif containing K |
| KLHL24 | kelch-like family member 24 |
| KRT20 | keratin 20, type I |
| LAMA4 | laminin, alpha 4 |
| LIF | leukemia inhibitory factor |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MATN1 | matrilin 1, cartilage matrix protein |
| MEP1B | meprin A, beta |
| MFSD7 | major facilitator superfamily domain containing 7 |
| MUC3B | mucin 3B, cell surface associated |
| MXD3 | MAX dimerization protein 3 |
| N4BP3 | NEDD4 binding protein 3 |
| NDUFA2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa |
| NEU3 | sialidase 3 (membrane sialidase) |
| NOX3 | NADPH oxidase 3 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| ORAI2 | ORAI calcium release-activated calcium modulator 2 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PDCD6 | programmed cell death 6 |
| PDLIM3 | PDZ and LIM domain 3 |
| PLD1 | phospholipase D1, phosphatidylcholine-specific |
| POU2F2 | POU class 2 homeobox 2 |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PSD4 | pleckstrin and Sec7 domain containing 4 |
| S100A13 | S100 calcium binding protein A13 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SLC22A17 | solute carrier family 22, member 17 |
| SLC35A2 | solute carrier family 35 (UDP-galactose transporter), member A2 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SP100 | SP100 nuclear antigen |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| SPTBN5 | spectrin, beta, non-erythrocytic 5 |
| STEAP4 | STEAP family member 4 |
| STMN4 | stathmin-like 4 |
| STON1 | stonin 1 |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TPMT | thiopurine S-methyltransferase |
| TREX1 | three prime repair exonuclease 1 |
| TRIM10 | tripartite motif containing 10 |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| TSPAN9 | tetraspanin 9 |
| TTC38 | tetratricopeptide repeat domain 38 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TXNIP | thioredoxin interacting protein |
| ZNF224 | zinc finger protein 224 |
| ZNF3 | zinc finger protein 3 |
| ZNF329 | zinc finger protein 329 |
| ZNF750 | zinc finger protein 750 |
| ZNF76 | zinc finger protein 76 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ABCA12 | ATP-binding cassette, sub-family A (ABC1), member 12 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
| ALPK1 | alpha-kinase 1 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BAX | BCL2-associated X protein |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CEP85 | centrosomal protein 85kDa |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLEC16A | C-type lectin domain family 16, member A |
| CRY2 | cryptochrome circadian clock 2 |
| CTPS1 | CTP synthase 1 |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DUSP8 | dual specificity phosphatase 8 |
| EVPL | envoplakin |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FADS2 | fatty acid desaturase 2 |
| FAM204A | family with sequence similarity 204, member A |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| FOSL1 | FOS-like antigen 1 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| GAMT | guanidinoacetate N-methyltransferase |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GLI3 | GLI family zinc finger 3 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HAUS6 | HAUS augmin-like complex, subunit 6 |
| HCFC1 | host cell factor C1 |
| HIST1H4D | histone cluster 1, H4d |
| HMOX1 | heme oxygenase 1 |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HOXB2 | homeobox B2 |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IFRD1 | interferon-related developmental regulator 1 |
| IFT54 | intraflagellar transport 54 |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| IL4R | interleukin 4 receptor |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KIAA0125 | KIAA0125 |
| KIAA0319L | KIAA0319-like |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| LOC157562 | uncharacterized LOC157562 |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MIR22HG | MIR22 host gene |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MUC3A | mucin 3A, cell surface associated |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive |
| NOP2 | NOP2 nucleolar protein |
| NOTCH1 | notch 1 |
| OLFML2A | olfactomedin-like 2A |
| ONECUT2 | one cut homeobox 2 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PER3 | period circadian clock 3 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLA2G3 | phospholipase A2, group III |
| PPAN | peter pan homolog (Drosophila) |
| PRMT7 | protein arginine methyltransferase 7 |
| PRR4 | proline rich 4 (lacrimal) |
| PTDSS2 | phosphatidylserine synthase 2 |
| PTPN9 | protein tyrosine phosphatase, non-receptor type 9 |
| RAB30 | RAB30, member RAS oncogene family |
| RGS19 | regulator of G-protein signaling 19 |
| RGS2 | regulator of G-protein signaling 2 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SCD5 | stearoyl-CoA desaturase 5 |
| SDC3 | syndecan 3 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 |
| SNHG3 | small nucleolar RNA host gene 3 |
| SPATA2L | spermatogenesis associated 2-like |
| STX1A | syntaxin 1A (brain) |
| TCTN2 | tectonic family member 2 |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TMEM120B | transmembrane protein 120B |
| TMEM121 | transmembrane protein 121 |
| TMEM242 | transmembrane protein 242 |
| TMEM39B | transmembrane protein 39B |
| TOE1 | target of EGR1, member 1 (nuclear) |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| UPK2 | uroplakin 2 |
| VASP | vasodilator-stimulated phosphoprotein |
| WDR76 | WD repeat domain 76 |
| WLS | wntless Wnt ligand secretion mediator |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF350 | zinc finger protein 350 |
| ZNF573 | zinc finger protein 573 |
| ZNF675 | zinc finger protein 675 |
| ZNF747 | zinc finger protein 747 |
