| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the sirolimus-5581 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACPP | acid phosphatase, prostate |
| ADCK3 | aarF domain containing kinase 3 |
| ADRA2B | adrenoceptor alpha 2B |
| ALDOB | aldolase B, fructose-bisphosphate |
| ANG | angiogenin, ribonuclease, RNase A family, 5 |
| ATP6V1B1 | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 |
| ATXN7L1 | ataxin 7-like 1 |
| BCL2 | B-cell CLL/lymphoma 2 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| C8ORF44 | chromosome 8 open reading frame 44 |
| CBX7 | chromobox homolog 7 |
| CCNG2 | cyclin G2 |
| CD48 | CD48 molecule |
| CD83 | CD83 molecule |
| CD8A | CD8a molecule |
| CDK19 | cyclin-dependent kinase 19 |
| CFAP70 | cilia and flagella associated protein 70 |
| CFHR4 | complement factor H-related 4 |
| CHI3L2 | chitinase 3-like 2 |
| CLDN17 | claudin 17 |
| CLEC4E | C-type lectin domain family 4, member E |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 |
| COL1A1 | collagen, type I, alpha 1 |
| CT62 | cancer/testis antigen 62 |
| CYHR1 | cysteine/histidine-rich 1 |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 |
| DIXDC1 | DIX domain containing 1 |
| DRD1 | dopamine receptor D1 |
| FAXDC2 | fatty acid hydroxylase domain containing 2 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GPER1 | G protein-coupled estrogen receptor 1 |
| GRM8 | glutamate receptor, metabotropic 8 |
| HIST1H3E | histone cluster 1, H3e |
| IFT27 | intraflagellar transport 27 |
| IL17RC | interleukin 17 receptor C |
| ING4 | inhibitor of growth family, member 4 |
| INSL4 | insulin-like 4 (placenta) |
| IRS2 | insulin receptor substrate 2 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
| KLHL24 | kelch-like family member 24 |
| KLK7 | kallikrein-related peptidase 7 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LPXN | leupaxin |
| LRP12 | low density lipoprotein receptor-related protein 12 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAK | male germ cell-associated kinase |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| METTL7A | methyltransferase like 7A |
| MFSD6 | major facilitator superfamily domain containing 6 |
| MMP11 | matrix metallopeptidase 11 |
| MR1 | major histocompatibility complex, class I-related |
| MUC6 | mucin 6, oligomeric mucus/gel-forming |
| MXD3 | MAX dimerization protein 3 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NRG2 | neuregulin 2 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PKLR | pyruvate kinase, liver and RBC |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PMEL | premelanosome protein |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PQBP1 | polyglutamine binding protein 1 |
| PRDM10 | PR domain containing 10 |
| PVRL1 | poliovirus receptor-related 1 (herpesvirus entry mediator C) |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| R3HDM1 | R3H domain containing 1 |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SH3GL3 | SH3-domain GRB2-like 3 |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| STON1 | stonin 1 |
| TM4SF4 | transmembrane 4 L six family member 4 |
| TREX1 | three prime repair exonuclease 1 |
| TXNIP | thioredoxin interacting protein |
| TYRP1 | tyrosinase-related protein 1 |
| WDR59 | WD repeat domain 59 |
| WIPI2 | WD repeat domain, phosphoinositide interacting 2 |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZNF287 | zinc finger protein 287 |
| ZNF682 | zinc finger protein 682 |
| Symbol | Name |
|---|---|
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ACSF2 | acyl-CoA synthetase family member 2 |
| AEN | apoptosis enhancing nuclease |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| BYSL | bystin-like |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CA11 | carbonic anhydrase XI |
| CBX8 | chromobox homolog 8 |
| CCDC86 | coiled-coil domain containing 86 |
| CD82 | CD82 molecule |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CEP72 | centrosomal protein 72kDa |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CRYGC | crystallin, gamma C |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DUSP8 | dual specificity phosphatase 8 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EFHD2 | EF-hand domain family, member D2 |
| ELK4 | ELK4, ETS-domain protein (SRF accessory protein 1) |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| FAM155B | family with sequence similarity 155, member B |
| FAM198B | family with sequence similarity 198, member B |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GAMT | guanidinoacetate N-methyltransferase |
| GHR | growth hormone receptor |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GMPR | guanosine monophosphate reductase |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| IFRD1 | interferon-related developmental regulator 1 |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LIN7A | lin-7 homolog A (C. elegans) |
| LRRC61 | leucine rich repeat containing 61 |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MCMBP | minichromosome maintenance complex binding protein |
| MIR22HG | MIR22 host gene |
| MYL5 | myosin, light chain 5, regulatory |
| NOL12 | nucleolar protein 12 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NXPH4 | neurexophilin 4 |
| ONECUT2 | one cut homeobox 2 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PADI1 | peptidyl arginine deiminase, type I |
| PARD6A | par-6 family cell polarity regulator alpha |
| PARG | poly (ADP-ribose) glycohydrolase |
| PDE8B | phosphodiesterase 8B |
| PLXNA3 | plexin A3 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PRSS53 | protease, serine, 53 |
| PTCD1 | pentatricopeptide repeat domain 1 |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| PVRL3 | poliovirus receptor-related 3 |
| QSER1 | glutamine and serine rich 1 |
| RAB3A | RAB3A, member RAS oncogene family |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RGS19 | regulator of G-protein signaling 19 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SLC10A3 | solute carrier family 10, member 3 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| SRPX | sushi-repeat containing protein, X-linked |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| SUSD4 | sushi domain containing 4 |
| SYBU | syntabulin (syntaxin-interacting) |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TMEM180 | transmembrane protein 180 |
| TRABD | TraB domain containing |
| TRAF2 | TNF receptor-associated factor 2 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| USB1 | U6 snRNA biogenesis 1 |
| USP20 | ubiquitin specific peptidase 20 |
| UTP20 | UTP20, small subunit (SSU) processome component, homolog (yeast) |
| WDR62 | WD repeat domain 62 |
| WLS | wntless Wnt ligand secretion mediator |
| XK | X-linked Kx blood group |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZFHX2 | zinc finger homeobox 2 |
| ZNF250 | zinc finger protein 250 |
| ZNF34 | zinc finger protein 34 |
