| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the sirolimus-5602 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ACOX2 | acyl-CoA oxidase 2, branched chain |
| ADAM12 | ADAM metallopeptidase domain 12 |
| ADCK3 | aarF domain containing kinase 3 |
| AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| ALS2CL | ALS2 C-terminal like |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
| APOC1 | apolipoprotein C-I |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARID1A | AT rich interactive domain 1A (SWI-like) |
| ASB1 | ankyrin repeat and SOCS box containing 1 |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| BEX4 | brain expressed, X-linked 4 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| C21ORF2 | chromosome 21 open reading frame 2 |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID |
| CCNG2 | cyclin G2 |
| CCRL2 | chemokine (C-C motif) receptor-like 2 |
| CDK19 | cyclin-dependent kinase 19 |
| CEL | carboxyl ester lipase |
| CEND1 | cell cycle exit and neuronal differentiation 1 |
| COL6A1 | collagen, type VI, alpha 1 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| CTH | cystathionine gamma-lyase |
| CYLD | cylindromatosis (turban tumor syndrome) |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DRD1 | dopamine receptor D1 |
| ECEL1 | endothelin converting enzyme-like 1 |
| EDNRA | endothelin receptor type A |
| EFCAB11 | EF-hand calcium binding domain 11 |
| EMP1 | epithelial membrane protein 1 |
| EXT1 | exostosin glycosyltransferase 1 |
| FAXDC2 | fatty acid hydroxylase domain containing 2 |
| FH | fumarate hydratase |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GJA9 | gap junction protein, alpha 9, 59kDa |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) |
| HLA-DOA | major histocompatibility complex, class II, DO alpha |
| HOXA10 | homeobox A10 |
| IFT27 | intraflagellar transport 27 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| ING4 | inhibitor of growth family, member 4 |
| INHBC | inhibin, beta C |
| IRS2 | insulin receptor substrate 2 |
| KIF13B | kinesin family member 13B |
| KLHL24 | kelch-like family member 24 |
| LONP2 | lon peptidase 2, peroxisomal |
| LTC4S | leukotriene C4 synthase |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAN2A2 | mannosidase, alpha, class 2A, member 2 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MOBP | myelin-associated oligodendrocyte basic protein |
| MPPE1 | metallophosphoesterase 1 |
| MTSS1L | metastasis suppressor 1-like |
| MXD3 | MAX dimerization protein 3 |
| MXD4 | MAX dimerization protein 4 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric |
| NDUFB7 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa |
| NF1 | neurofibromin 1 |
| NIPSNAP3B | nipsnap homolog 3B (C. elegans) |
| NPAS1 | neuronal PAS domain protein 1 |
| OR10H1 | olfactory receptor, family 10, subfamily H, member 1 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PDLIM5 | PDZ and LIM domain 5 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PMEL | premelanosome protein |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PSCA | prostate stem cell antigen |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| RALGPS1 | Ral GEF with PH domain and SH3 binding motif 1 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 |
| RORC | RAR-related orphan receptor C |
| RPLP2 | ribosomal protein, large, P2 |
| RUNX1 | runt-related transcription factor 1 |
| SH3GL3 | SH3-domain GRB2-like 3 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SLCO2B1 | solute carrier organic anion transporter family, member 2B1 |
| SPG20 | spastic paraplegia 20 (Troyer syndrome) |
| SSPN | sarcospan |
| STON1 | stonin 1 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TM4SF4 | transmembrane 4 L six family member 4 |
| TPMT | thiopurine S-methyltransferase |
| TRAK1 | trafficking protein, kinesin binding 1 |
| TSC22D2 | TSC22 domain family, member 2 |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| TXNIP | thioredoxin interacting protein |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| VASH2 | vasohibin 2 |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |
| Symbol | Name |
|---|---|
| ADAMTS13 | ADAM metallopeptidase with thrombospondin type 1 motif, 13 |
| AHCYL2 | adenosylhomocysteinase-like 2 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| APOBEC1 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C19ORF24 | chromosome 19 open reading frame 24 |
| C5AR2 | complement component 5a receptor 2 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CD1A | CD1a molecule |
| CEP112 | centrosomal protein 112kDa |
| CEP72 | centrosomal protein 72kDa |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLDN15 | claudin 15 |
| CORO1A | coronin, actin binding protein, 1A |
| CRLF1 | cytokine receptor-like factor 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DOK5 | docking protein 5 |
| EFHD2 | EF-hand domain family, member D2 |
| EFNA3 | ephrin-A3 |
| FAM120C | family with sequence similarity 120C |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FHIT | fragile histidine triad |
| FLJ22184 | |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GALK1 | galactokinase 1 |
| GAN | gigaxonin |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GPATCH3 | G patch domain containing 3 |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HOXB2 | homeobox B2 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| HYI | hydroxypyruvate isomerase (putative) |
| IFRD1 | interferon-related developmental regulator 1 |
| INO80D | INO80 complex subunit D |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| KRT15 | keratin 15, type I |
| KRT31 | keratin 31, type I |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| LPAR3 | lysophosphatidic acid receptor 3 |
| LRRC61 | leucine rich repeat containing 61 |
| LRRTM2 | leucine rich repeat transmembrane neuronal 2 |
| LTBP3 | latent transforming growth factor beta binding protein 3 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAP6D1 | MAP6 domain containing 1 |
| MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MCOLN1 | mucolipin 1 |
| MUC3A | mucin 3A, cell surface associated |
| NOL10 | nucleolar protein 10 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NOP2 | NOP2 nucleolar protein |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPR3 | natriuretic peptide receptor 3 |
| OLFML2A | olfactomedin-like 2A |
| PAK1IP1 | PAK1 interacting protein 1 |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PDE8B | phosphodiesterase 8B |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLSCR4 | phospholipid scramblase 4 |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRPH | peripherin |
| PRSS22 | protease, serine, 22 |
| PRSS53 | protease, serine, 53 |
| RAB3A | RAB3A, member RAS oncogene family |
| RELN | reelin |
| RGS2 | regulator of G-protein signaling 2 |
| RHBG | Rh family, B glycoprotein (gene/pseudogene) |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF25 | ring finger protein 25 |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| S100A9 | S100 calcium binding protein A9 |
| SAA4 | serum amyloid A4, constitutive |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SPATA2L | spermatogenesis associated 2-like |
| SSTR4 | somatostatin receptor 4 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TGFBR3 | transforming growth factor, beta receptor III |
| TRAF5 | TNF receptor-associated factor 5 |
| TUBA3C | tubulin, alpha 3c |
| UPP1 | uridine phosphorylase 1 |
| UTP20 | UTP20, small subunit (SSU) processome component, homolog (yeast) |
| WLS | wntless Wnt ligand secretion mediator |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZFHX2 | zinc finger homeobox 2 |
| ZFHX4 | zinc finger homeobox 4 |
| ZNF204P | zinc finger protein 204, pseudogene |
| ZNF516 | zinc finger protein 516 |
| ZNF639 | zinc finger protein 639 |
| ZXDB | zinc finger, X-linked, duplicated B |
