| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the sirolimus-5927 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AGPAT2 | 1-acylglycerol-3-phosphate O-acyltransferase 2 |
| AJAP1 | adherens junctions associated protein 1 |
| AKAP7 | A kinase (PRKA) anchor protein 7 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| ALOX5 | arachidonate 5-lipoxygenase |
| AP4E1 | adaptor-related protein complex 4, epsilon 1 subunit |
| APCS | amyloid P component, serum |
| ARC | activity-regulated cytoskeleton-associated protein |
| ASIC1 | acid sensing (proton gated) ion channel 1 |
| ATXN3 | ataxin 3 |
| AUTS2 | autism susceptibility candidate 2 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| C8ORF17 | chromosome 8 open reading frame 17 |
| CD22 | CD22 molecule |
| CD52 | CD52 molecule |
| CEP152 | centrosomal protein 152kDa |
| CHRNA10 | cholinergic receptor, nicotinic, alpha 10 (neuronal) |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| COL1A2 | collagen, type I, alpha 2 |
| CREB1 | cAMP responsive element binding protein 1 |
| CYP3A4 | cytochrome P450, family 3, subfamily A, polypeptide 4 |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| DST | dystonin |
| ECM1 | extracellular matrix protein 1 |
| EMID1 | EMI domain containing 1 |
| EMP1 | epithelial membrane protein 1 |
| ENO3 | enolase 3 (beta, muscle) |
| ESR1 | estrogen receptor 1 |
| ETV6 | ets variant 6 |
| FAM110B | family with sequence similarity 110, member B |
| FAM214B | family with sequence similarity 214, member B |
| FBRS | fibrosin |
| FGF13 | fibroblast growth factor 13 |
| FOLH1 | folate hydrolase (prostate-specific membrane antigen) 1 |
| FUT7 | fucosyltransferase 7 (alpha (1,3) fucosyltransferase) |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) |
| GLP1R | glucagon-like peptide 1 receptor |
| GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 |
| GRIP2 | glutamate receptor interacting protein 2 |
| HEY2 | hes-related family bHLH transcription factor with YRPW motif 2 |
| HOXB2 | homeobox B2 |
| KALRN | kalirin, RhoGEF kinase |
| KCNA3 | potassium channel, voltage gated shaker related subfamily A, member 3 |
| KCNQ1 | potassium channel, voltage gated KQT-like subfamily Q, member 1 |
| KIAA0125 | KIAA0125 |
| KIAA0391 | KIAA0391 |
| KRT8 | keratin 8, type II |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LRRC40 | leucine rich repeat containing 40 |
| LTB4R | leukotriene B4 receptor |
| MAP4 | microtubule-associated protein 4 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MXD4 | MAX dimerization protein 4 |
| NNAT | neuronatin |
| NOL10 | nucleolar protein 10 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PLAC4 | placenta-specific 4 |
| PLEC | plectin |
| PORCN | porcupine homolog (Drosophila) |
| POU3F4 | POU class 3 homeobox 4 |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta |
| PTPRH | protein tyrosine phosphatase, receptor type, H |
| RUSC2 | RUN and SH3 domain containing 2 |
| SCARA3 | scavenger receptor class A, member 3 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SECTM1 | secreted and transmembrane 1 |
| SELL | selectin L |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
| SERHL2 | serine hydrolase-like 2 |
| SFTPD | surfactant protein D |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SIPA1 | signal-induced proliferation-associated 1 |
| SLC12A3 | solute carrier family 12 (sodium/chloride transporter), member 3 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SLC35A2 | solute carrier family 35 (UDP-galactose transporter), member A2 |
| SLC6A2 | solute carrier family 6 (neurotransmitter transporter), member 2 |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| SRPR | signal recognition particle receptor (docking protein) |
| STAC | SH3 and cysteine rich domain |
| TEP1 | telomerase-associated protein 1 |
| THRA | thyroid hormone receptor, alpha |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TMEM63A | transmembrane protein 63A |
| TONSL | tonsoku-like, DNA repair protein |
| UPK3B | uroplakin 3B |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| WNT2B | wingless-type MMTV integration site family, member 2B |
| ZMYM6 | zinc finger, MYM-type 6 |
| ZNF552 | zinc finger protein 552 |
| ZNF821 | zinc finger protein 821 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ACTN4 | actinin, alpha 4 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| ALOX15 | arachidonate 15-lipoxygenase |
| APPL2 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 |
| ARSB | arylsulfatase B |
| ATG9A | autophagy related 9A |
| BAG4 | BCL2-associated athanogene 4 |
| BIRC7 | baculoviral IAP repeat containing 7 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID |
| CCDC85C | coiled-coil domain containing 85C |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CEP85 | centrosomal protein 85kDa |
| CES3 | carboxylesterase 3 |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CKMT2 | creatine kinase, mitochondrial 2 (sarcomeric) |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CSF1R | colony stimulating factor 1 receptor |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CYP4F8 | cytochrome P450, family 4, subfamily F, polypeptide 8 |
| DLK1 | delta-like 1 homolog (Drosophila) |
| DNASE1L3 | deoxyribonuclease I-like 3 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EAF2 | ELL associated factor 2 |
| EFNA3 | ephrin-A3 |
| ELSPBP1 | epididymal sperm binding protein 1 |
| EN2 | engrailed homeobox 2 |
| ERCC2 | excision repair cross-complementation group 2 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FADS2 | fatty acid desaturase 2 |
| FAM120C | family with sequence similarity 120C |
| FGF4 | fibroblast growth factor 4 |
| FKBP14 | FK506 binding protein 14, 22 kDa |
| FUBP3 | far upstream element (FUSE) binding protein 3 |
| FZD3 | frizzled class receptor 3 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GAPDHS | glyceraldehyde-3-phosphate dehydrogenase, spermatogenic |
| GLDC | glycine dehydrogenase (decarboxylating) |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GRB7 | growth factor receptor-bound protein 7 |
| HOXA4 | homeobox A4 |
| HOXC4 | homeobox C4 |
| INCENP | inner centromere protein antigens 135/155kDa |
| INO80D | INO80 complex subunit D |
| IQCG | IQ motif containing G |
| KIAA1456 | KIAA1456 |
| KRT15 | keratin 15, type I |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MORN1 | MORN repeat containing 1 |
| MPDU1 | mannose-P-dolichol utilization defect 1 |
| NAA16 | N(alpha)-acetyltransferase 16, NatA auxiliary subunit |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PADI1 | peptidyl arginine deiminase, type I |
| PCBP3 | poly(rC) binding protein 3 |
| PDE9A | phosphodiesterase 9A |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| POGK | pogo transposable element with KRAB domain |
| POLM | polymerase (DNA directed), mu |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRF1 | perforin 1 (pore forming protein) |
| PRKCE | protein kinase C, epsilon |
| PRR3 | proline rich 3 |
| PRRG2 | proline rich Gla (G-carboxyglutamic acid) 2 |
| PSKH1 | protein serine kinase H1 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAB23 | RAB23, member RAS oncogene family |
| RAB3A | RAB3A, member RAS oncogene family |
| RHBG | Rh family, B glycoprotein (gene/pseudogene) |
| RNF25 | ring finger protein 25 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SH3GLB2 | SH3-domain GRB2-like endophilin B2 |
| SLC52A1 | solute carrier family 52 (riboflavin transporter), member 1 |
| TBC1D31 | TBC1 domain family, member 31 |
| TFF2 | trefoil factor 2 |
| TMC7 | transmembrane channel-like 7 |
| TRABD | TraB domain containing |
| TUBA4B | tubulin, alpha 4b |
| WNT1 | wingless-type MMTV integration site family, member 1 |
| YIPF5 | Yip1 domain family, member 5 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZNF212 | zinc finger protein 212 |
| ZNF76 | zinc finger protein 76 |
