| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the sirolimus-5932 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABR | active BCR-related |
| ACVR2B | activin A receptor, type IIB |
| ADAM10 | ADAM metallopeptidase domain 10 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ARSD | arylsulfatase D |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| ASB7 | ankyrin repeat and SOCS box containing 7 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 |
| C16ORF58 | chromosome 16 open reading frame 58 |
| C1RL | complement component 1, r subcomponent-like |
| C20ORF195 | chromosome 20 open reading frame 195 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CCDC28A | coiled-coil domain containing 28A |
| CCNG2 | cyclin G2 |
| CCPG1 | cell cycle progression 1 |
| CDC25C | cell division cycle 25C |
| CDK19 | cyclin-dependent kinase 19 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CLEC11A | C-type lectin domain family 11, member A |
| DENND3 | DENN/MADD domain containing 3 |
| DNAH3 | dynein, axonemal, heavy chain 3 |
| DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 |
| DNAL4 | dynein, axonemal, light chain 4 |
| EFNB1 | ephrin-B1 |
| EPOR | erythropoietin receptor |
| FLI1 | Fli-1 proto-oncogene, ETS transcription factor |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GALK2 | galactokinase 2 |
| GFOD2 | glucose-fructose oxidoreductase domain containing 2 |
| GLB1L | galactosidase, beta 1-like |
| GPR19 | G protein-coupled receptor 19 |
| GREM1 | gremlin 1, DAN family BMP antagonist |
| GSTM4 | glutathione S-transferase mu 4 |
| GZMK | granzyme K (granzyme 3; tryptase II) |
| HAUS5 | HAUS augmin-like complex, subunit 5 |
| HEATR6 | HEAT repeat containing 6 |
| HNMT | histamine N-methyltransferase |
| HPS4 | Hermansky-Pudlak syndrome 4 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFT27 | intraflagellar transport 27 |
| IL17RC | interleukin 17 receptor C |
| ING4 | inhibitor of growth family, member 4 |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
| KDM6B | lysine (K)-specific demethylase 6B |
| KLHL24 | kelch-like family member 24 |
| KRT15 | keratin 15, type I |
| LRRK1 | leucine-rich repeat kinase 1 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MCTP2 | multiple C2 domains, transmembrane 2 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MT1HL1 | metallothionein 1H-like 1 |
| MT1M | metallothionein 1M |
| MUC3B | mucin 3B, cell surface associated |
| MXD3 | MAX dimerization protein 3 |
| MYL5 | myosin, light chain 5, regulatory |
| MYO1B | myosin IB |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NXT2 | nuclear transport factor 2-like export factor 2 |
| PARVA | parvin, alpha |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PFDN4 | prefoldin subunit 4 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PML | promyelocytic leukemia |
| POLL | polymerase (DNA directed), lambda |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PPARD | peroxisome proliferator-activated receptor delta |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) |
| PRPH | peripherin |
| PRR4 | proline rich 4 (lacrimal) |
| PTHLH | parathyroid hormone-like hormone |
| PTPN18 | protein tyrosine phosphatase, non-receptor type 18 (brain-derived) |
| RNASE4 | ribonuclease, RNase A family, 4 |
| RNF170 | ring finger protein 170 |
| RNMT | RNA (guanine-7-) methyltransferase |
| SIX2 | SIX homeobox 2 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SNAPC5 | small nuclear RNA activating complex, polypeptide 5, 19kDa |
| STON1 | stonin 1 |
| SYNJ2 | synaptojanin 2 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TMEM53 | transmembrane protein 53 |
| TMEM8B | transmembrane protein 8B |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| UNC13A | unc-13 homolog A (C. elegans) |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| VCAN | versican |
| VGLL3 | vestigial-like family member 3 |
| WDR48 | WD repeat domain 48 |
| WIPF1 | WAS/WASL interacting protein family, member 1 |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| AMPH | amphiphysin |
| ART1 | ADP-ribosyltransferase 1 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C8A | complement component 8, alpha polypeptide |
| CA9 | carbonic anhydrase IX |
| CADPS2 | Ca++-dependent secretion activator 2 |
| CCDC57 | coiled-coil domain containing 57 |
| CCNO | cyclin O |
| CD1C | CD1c molecule |
| CDIP1 | cell death-inducing p53 target 1 |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CHRDL1 | chordin-like 1 |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CPNE7 | copine VII |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DSCAM | Down syndrome cell adhesion molecule |
| EHF | ets homologous factor |
| EXOSC1 | exosome component 1 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| F2RL3 | coagulation factor II (thrombin) receptor-like 3 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM53B | family with sequence similarity 53, member B |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPR1 | G protein-coupled receptor 1 |
| GPT | glutamic-pyruvate transaminase (alanine aminotransferase) |
| HCN4 | hyperpolarization activated cyclic nucleotide gated potassium channel 4 |
| HIST1H1T | histone cluster 1, H1t |
| HIST1H2AL | histone cluster 1, H2al |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HOXA3 | homeobox A3 |
| IL17RA | interleukin 17 receptor A |
| IL7R | interleukin 7 receptor |
| INHA | inhibin, alpha |
| KRT4 | keratin 4, type II |
| LOC257152 | uncharacterized LOC257152 |
| LPPR4 | lipid phosphate phosphatase-related protein type 4 |
| MAGIX | MAGI family member, X-linked |
| MAGOHB | mago-nashi homolog B (Drosophila) |
| METTL1 | methyltransferase like 1 |
| MFI2 | antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 |
| MICALL2 | MICAL-like 2 |
| MIR622 | microRNA 622 |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MMP9 | matrix metallopeptidase 9 |
| MTCP1 | mature T-cell proliferation 1 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming |
| NAA16 | N(alpha)-acetyltransferase 16, NatA auxiliary subunit |
| NABP1 | nucleic acid binding protein 1 |
| NEUROD4 | neuronal differentiation 4 |
| OR10H1 | olfactory receptor, family 10, subfamily H, member 1 |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PRR14L | proline rich 14-like |
| PRR7 | proline rich 7 (synaptic) |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| PUS1 | pseudouridylate synthase 1 |
| RAB36 | RAB36, member RAS oncogene family |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| REC8 | REC8 meiotic recombination protein |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RPA4 | replication protein A4, 30kDa |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| SAMHD1 | SAM domain and HD domain 1 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCIN | scinderin |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SH3GL2 | SH3-domain GRB2-like 2 |
| SHC3 | SHC (Src homology 2 domain containing) transforming protein 3 |
| SIRAL2 | SIR2 antiphage like 2 |
| SLC17A4 | solute carrier family 17, member 4 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| SNRPN | small nuclear ribonucleoprotein polypeptide N |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| STAB2 | stabilin 2 |
| STC2 | stanniocalcin 2 |
| TADA2A | transcriptional adaptor 2A |
| TGM1 | transglutaminase 1 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) |
| TLR2 | toll-like receptor 2 |
| TOM1 | target of myb1 (chicken) |
| TOMM40 | translocase of outer mitochondrial membrane 40 homolog (yeast) |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TUBA4B | tubulin, alpha 4b |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| WDR3 | WD repeat domain 3 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| ZNF215 | zinc finger protein 215 |
| ZNF253 | zinc finger protein 253 |
| ZNF668 | zinc finger protein 668 |
| ZNF749 | zinc finger protein 749 |
| ZNF768 | zinc finger protein 768 |
| ZNF778 | zinc finger protein 778 |
