| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the sirolimus-5975 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| AMPD1 | adenosine monophosphate deaminase 1 |
| AMT | aminomethyltransferase |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| AP1S2 | adaptor-related protein complex 1, sigma 2 subunit |
| ARL3 | ADP-ribosylation factor-like 3 |
| ARRB1 | arrestin, beta 1 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| C6ORF62 | chromosome 6 open reading frame 62 |
| CCNG2 | cyclin G2 |
| CCNO | cyclin O |
| CD1E | CD1e molecule |
| CDK13 | cyclin-dependent kinase 13 |
| CDK2 | cyclin-dependent kinase 2 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 |
| DEDD | death effector domain containing |
| DSTYK | dual serine/threonine and tyrosine protein kinase |
| DTNA | dystrobrevin, alpha |
| EPOR | erythropoietin receptor |
| ERP44 | endoplasmic reticulum protein 44 |
| EXOC7 | exocyst complex component 7 |
| FGF2 | fibroblast growth factor 2 (basic) |
| FGFR1 | fibroblast growth factor receptor 1 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GLB1L | galactosidase, beta 1-like |
| GPR21 | G protein-coupled receptor 21 |
| HBP1 | HMG-box transcription factor 1 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2AJ | histone cluster 1, H2aj |
| HN1L | hematological and neurological expressed 1-like |
| HOXA10 | homeobox A10 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
| KCNK5 | potassium channel, two pore domain subfamily K, member 5 |
| KIF1A | kinesin family member 1A |
| KLHL24 | kelch-like family member 24 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| LDLR | low density lipoprotein receptor |
| LIN7B | lin-7 homolog B (C. elegans) |
| LRRC14 | leucine rich repeat containing 14 |
| MAPK1IP1L | mitogen-activated protein kinase 1 interacting protein 1-like |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 |
| MEF2D | myocyte enhancer factor 2D |
| MEGF6 | multiple EGF-like-domains 6 |
| MLLT4-AS1 | MLLT4 antisense RNA 1 (head to head) |
| MST1 | macrophage stimulating 1 |
| NCKAP1 | NCK-associated protein 1 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NFIB | nuclear factor I/B |
| NFX1 | nuclear transcription factor, X-box binding 1 |
| NME5 | NME/NM23 family member 5 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PGAP3 | post-GPI attachment to proteins 3 |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PICALM | phosphatidylinositol binding clathrin assembly protein |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PITX1 | paired-like homeodomain 1 |
| POT1 | protection of telomeres 1 |
| PPP2R5D | protein phosphatase 2, regulatory subunit B', delta |
| PSD3 | pleckstrin and Sec7 domain containing 3 |
| QKI | QKI, KH domain containing, RNA binding |
| RARG | retinoic acid receptor, gamma |
| RGS10 | regulator of G-protein signaling 10 |
| ROM1 | retinal outer segment membrane protein 1 |
| SCAMP1 | secretory carrier membrane protein 1 |
| SCYL2 | SCY1-like 2 (S. cerevisiae) |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SIRT3 | sirtuin 3 |
| SKIL | SKI-like proto-oncogene |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SPAG9 | sperm associated antigen 9 |
| SRPR | signal recognition particle receptor (docking protein) |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa |
| TAZ | tafazzin |
| TDRKH | tudor and KH domain containing |
| TMED2 | transmembrane emp24 domain trafficking protein 2 |
| TMEM230 | transmembrane protein 230 |
| TNFRSF10C | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TRIM5 | tripartite motif containing 5 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 |
| TXNIP | thioredoxin interacting protein |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZNF510 | zinc finger protein 510 |
| ZNF586 | zinc finger protein 586 |
| Symbol | Name |
|---|---|
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ADAP2 | ArfGAP with dual PH domains 2 |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ASIC4 | acid sensing (proton gated) ion channel family member 4 |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| ATP2A1 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 |
| BAG4 | BCL2-associated athanogene 4 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| CACNG3 | calcium channel, voltage-dependent, gamma subunit 3 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CCRL2 | chemokine (C-C motif) receptor-like 2 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CD83 | CD83 molecule |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CNTN5 | contactin 5 |
| CORO7 | coronin 7 |
| CPNE7 | copine VII |
| CTRL | chymotrypsin-like |
| DAAM2 | dishevelled associated activator of morphogenesis 2 |
| DCUN1D2 | DCN1, defective in cullin neddylation 1, domain containing 2 |
| DSPP | dentin sialophosphoprotein |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| EDAR | ectodysplasin A receptor |
| ELAVL2 | ELAV like neuron-specific RNA binding protein 2 |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| FBXO2 | F-box protein 2 |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FLCN | folliculin |
| FOSL1 | FOS-like antigen 1 |
| GFAP | glial fibrillary acidic protein |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GRIP2 | glutamate receptor interacting protein 2 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HLA-DQB2 | major histocompatibility complex, class II, DQ beta 2 |
| IFT54 | intraflagellar transport 54 |
| IL17RA | interleukin 17 receptor A |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| ITM2C | integral membrane protein 2C |
| KRT15 | keratin 15, type I |
| LAMP5 | lysosomal-associated membrane protein family, member 5 |
| LHX3 | LIM homeobox 3 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LOC729164 | hCG1732469 |
| LRP4 | low density lipoprotein receptor-related protein 4 |
| LRRTM2 | leucine rich repeat transmembrane neuronal 2 |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MTERF4 | mitochondrial transcription termination factor 4 |
| NPHS2 | nephrosis 2, idiopathic, steroid-resistant (podocin) |
| NXPH4 | neurexophilin 4 |
| OGDHL | oxoglutarate dehydrogenase-like |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| PCBP3 | poly(rC) binding protein 3 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PODNL1 | podocan-like 1 |
| POLH | polymerase (DNA directed), eta |
| POU3F2 | POU class 3 homeobox 2 |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PRSS53 | protease, serine, 53 |
| PSAT1 | phosphoserine aminotransferase 1 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| RAB3A | RAB3A, member RAS oncogene family |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RORC | RAR-related orphan receptor C |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SHPK | sedoheptulokinase |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SOCS7 | suppressor of cytokine signaling 7 |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| ST5 | suppression of tumorigenicity 5 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| TMEM180 | transmembrane protein 180 |
| TMPRSS4 | transmembrane protease, serine 4 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| UNC13A | unc-13 homolog A (C. elegans) |
| USB1 | U6 snRNA biogenesis 1 |
| USP6NL | USP6 N-terminal like |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| VIM | vimentin |
| WDR4 | WD repeat domain 4 |
| ZDHHC18 | zinc finger, DHHC-type containing 18 |
| ZNF254 | zinc finger protein 254 |
| ZNF286A | zinc finger protein 286A |
| ZNF423 | zinc finger protein 423 |
