| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the sirolimus-5980 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AADAC | arylacetamide deacetylase |
| ACPP | acid phosphatase, prostate |
| ADRA1D | adrenoceptor alpha 1D |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| AMBRA1 | autophagy/beclin-1 regulator 1 |
| ANKRD36B | ankyrin repeat domain 36B |
| ARL14 | ADP-ribosylation factor-like 14 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| BCAS3 | breast carcinoma amplified sequence 3 |
| BTN3A1 | butyrophilin, subfamily 3, member A1 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| C10ORF10 | chromosome 10 open reading frame 10 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C1S | complement component 1, s subcomponent |
| CCDC28A | coiled-coil domain containing 28A |
| CDK18 | cyclin-dependent kinase 18 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CEACAM3 | carcinoembryonic antigen-related cell adhesion molecule 3 |
| CEP295 | centrosomal protein 295kDa |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| COL3A1 | collagen, type III, alpha 1 |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| CYLD | cylindromatosis (turban tumor syndrome) |
| DHODH | dihydroorotate dehydrogenase (quinone) |
| DOCK6 | dedicator of cytokinesis 6 |
| EFNA3 | ephrin-A3 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ETV1 | ets variant 1 |
| FAM63A | family with sequence similarity 63, member A |
| FGFR1 | fibroblast growth factor receptor 1 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FLT1 | fms-related tyrosine kinase 1 |
| GAL | galanin/GMAP prepropeptide |
| GAS2L1 | growth arrest-specific 2 like 1 |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 |
| HBP1 | HMG-box transcription factor 1 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HOXA6 | homeobox A6 |
| IL11 | interleukin 11 |
| IL17RA | interleukin 17 receptor A |
| IL33 | interleukin 33 |
| ING4 | inhibitor of growth family, member 4 |
| KANK3 | KN motif and ankyrin repeat domains 3 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIAA0319L | KIAA0319-like |
| KIRREL | kin of IRRE like (Drosophila) |
| KLF12 | Kruppel-like factor 12 |
| KLF2 | Kruppel-like factor 2 |
| KLHL24 | kelch-like family member 24 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 |
| MAPK11 | mitogen-activated protein kinase 11 |
| MAPK8IP2 | mitogen-activated protein kinase 8 interacting protein 2 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MEGF8 | multiple EGF-like-domains 8 |
| MMP11 | matrix metallopeptidase 11 |
| MRPS12 | mitochondrial ribosomal protein S12 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| PALM | paralemmin |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 |
| PGLYRP4 | peptidoglycan recognition protein 4 |
| PPARD | peroxisome proliferator-activated receptor delta |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| RASAL2 | RAS protein activator like 2 |
| RTCA | RNA 3'-terminal phosphate cyclase |
| RXRB | retinoid X receptor, beta |
| SCD5 | stearoyl-CoA desaturase 5 |
| SERHL2 | serine hydrolase-like 2 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| STON1 | stonin 1 |
| TAT | tyrosine aminotransferase |
| TFEB | transcription factor EB |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| THRA | thyroid hormone receptor, alpha |
| TMEM209 | transmembrane protein 209 |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| TRANK1 | tetratricopeptide repeat and ankyrin repeat containing 1 |
| TREX1 | three prime repair exonuclease 1 |
| TRIM3 | tripartite motif containing 3 |
| TROVE2 | TROVE domain family, member 2 |
| VCAN | versican |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase |
| YPEL1 | yippee-like 1 (Drosophila) |
| YTHDC1 | YTH domain containing 1 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 |
| Symbol | Name |
|---|---|
| ABCA11P | ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene |
| ACSBG2 | acyl-CoA synthetase bubblegum family member 2 |
| AIRE | autoimmune regulator |
| APOH | apolipoprotein H (beta-2-glycoprotein I) |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| ATAD3A | ATPase family, AAA domain containing 3A |
| AUTS2 | autism susceptibility candidate 2 |
| BMP4 | bone morphogenetic protein 4 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C19ORF26 | chromosome 19 open reading frame 26 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CD79A | CD79a molecule, immunoglobulin-associated alpha |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CIDEB | cell death-inducing DFFA-like effector b |
| DPF3 | D4, zinc and double PHD fingers, family 3 |
| DSCAM | Down syndrome cell adhesion molecule |
| EVI2B | ecotropic viral integration site 2B |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| GALK1 | galactokinase 1 |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| HIST1H1T | histone cluster 1, H1t |
| IGFBP1 | insulin-like growth factor binding protein 1 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KISS1 | KiSS-1 metastasis-suppressor |
| KLF15 | Kruppel-like factor 15 |
| KLHL25 | kelch-like family member 25 |
| KLHL29 | kelch-like family member 29 |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LIPG | lipase, endothelial |
| LMTK2 | lemur tyrosine kinase 2 |
| LPPR1 | lipid phosphate phosphatase-related protein type 1 |
| LTC4S | leukotriene C4 synthase |
| MADCAM1 | mucosal vascular addressin cell adhesion molecule 1 |
| METTL1 | methyltransferase like 1 |
| MSI1 | musashi RNA-binding protein 1 |
| MTA2 | metastasis associated 1 family, member 2 |
| MYOC | myocilin, trabecular meshwork inducible glucocorticoid response |
| NAG18 | NAG18 mRNA |
| NCALD | neurocalcin delta |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) |
| NGF | nerve growth factor (beta polypeptide) |
| NID2 | nidogen 2 (osteonidogen) |
| NME5 | NME/NM23 family member 5 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| OSMR | oncostatin M receptor |
| PARP6 | poly (ADP-ribose) polymerase family, member 6 |
| PDE8B | phosphodiesterase 8B |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PROL1 | proline rich, lacrimal 1 |
| PRSS22 | protease, serine, 22 |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| RAB36 | RAB36, member RAS oncogene family |
| RABEPK | Rab9 effector protein with kelch motifs |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SMIM14 | small integral membrane protein 14 |
| SOSTDC1 | sclerostin domain containing 1 |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TAS2R1 | taste receptor, type 2, member 1 |
| TBKBP1 | TBK1 binding protein 1 |
| TCTN2 | tectonic family member 2 |
| TMEM144 | transmembrane protein 144 |
| TRIM25 | tripartite motif containing 25 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| VGF | VGF nerve growth factor inducible |
| VNN2 | vanin 2 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WDR3 | WD repeat domain 3 |
| WDR33 | WD repeat domain 33 |
| WFDC2 | WAP four-disulfide core domain 2 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| XYLT1 | xylosyltransferase I |
| ZNF205 | zinc finger protein 205 |
| ZNF215 | zinc finger protein 215 |
| ZNF385D | zinc finger protein 385D |
| ZNF428 | zinc finger protein 428 |
| ZNF711 | zinc finger protein 711 |
| ZXDB | zinc finger, X-linked, duplicated B |
