| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the sirolimus-6927 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADCK3 | aarF domain containing kinase 3 |
| ADRBK1 | adrenergic, beta, receptor kinase 1 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 |
| AP2A2 | adaptor-related protein complex 2, alpha 2 subunit |
| ASTN2 | astrotactin 2 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BTD | biotinidase |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CCDC28A | coiled-coil domain containing 28A |
| CCNG2 | cyclin G2 |
| CCNO | cyclin O |
| CD58 | CD58 molecule |
| CHKB | choline kinase beta |
| CHMP6 | charged multivesicular body protein 6 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| COPE | coatomer protein complex, subunit epsilon |
| COQ7 | coenzyme Q7 homolog, ubiquinone (yeast) |
| CPE | carboxypeptidase E |
| DEDD | death effector domain containing |
| EMID1 | EMI domain containing 1 |
| EPHA2 | EPH receptor A2 |
| ESR1 | estrogen receptor 1 |
| FAM63A | family with sequence similarity 63, member A |
| FAS | Fas cell surface death receptor |
| FGFR2 | fibroblast growth factor receptor 2 |
| FRAT1 | frequently rearranged in advanced T-cell lymphomas 1 |
| FZD7 | frizzled class receptor 7 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
| GFER | growth factor, augmenter of liver regeneration |
| GLRX | glutaredoxin (thioltransferase) |
| GPR85 | G protein-coupled receptor 85 |
| GYPB | glycophorin B (MNS blood group) |
| HIST1H2BO | histone cluster 1, H2bo |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| HMHA1 | histocompatibility (minor) HA-1 |
| IBSP | integrin-binding sialoprotein |
| IFT27 | intraflagellar transport 27 |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KIAA0125 | KIAA0125 |
| KIF13B | kinesin family member 13B |
| KLHL22 | kelch-like family member 22 |
| KLHL24 | kelch-like family member 24 |
| MBTD1 | mbt domain containing 1 |
| MED14 | mediator complex subunit 14 |
| MEIS1 | Meis homeobox 1 |
| MIIP | migration and invasion inhibitory protein |
| MR1 | major histocompatibility complex, class I-related |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NEBL | nebulette |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| OR10C1 | olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene) |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDIA2 | protein disulfide isomerase family A, member 2 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| POLR2J4 | polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene |
| POT1 | protection of telomeres 1 |
| PRLR | prolactin receptor |
| PROSC | proline synthetase co-transcribed homolog (bacterial) |
| PSD4 | pleckstrin and Sec7 domain containing 4 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 |
| QKI | QKI, KH domain containing, RNA binding |
| RALGDS | ral guanine nucleotide dissociation stimulator |
| REEP1 | receptor accessory protein 1 |
| REPS2 | RALBP1 associated Eps domain containing 2 |
| RHEB | Ras homolog enriched in brain |
| RUNX1 | runt-related transcription factor 1 |
| S100A9 | S100 calcium binding protein A9 |
| SCARB2 | scavenger receptor class B, member 2 |
| SEC14L5 | SEC14-like 5 (S. cerevisiae) |
| SHARPIN | SHANK-associated RH domain interactor |
| SIK3 | SIK family kinase 3 |
| SLC41A3 | solute carrier family 41, member 3 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| SSH3 | slingshot protein phosphatase 3 |
| TMEM53 | transmembrane protein 53 |
| TRAK1 | trafficking protein, kinesin binding 1 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TSC22D4 | TSC22 domain family, member 4 |
| TTC9 | tetratricopeptide repeat domain 9 |
| TXNIP | thioredoxin interacting protein |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) |
| VAX2 | ventral anterior homeobox 2 |
| WDR1 | WD repeat domain 1 |
| WDR91 | WD repeat domain 91 |
| ZHX3 | zinc fingers and homeoboxes 3 |
| ZNF224 | zinc finger protein 224 |
| ZNF365 | zinc finger protein 365 |
| ZNF446 | zinc finger protein 446 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 |
| Symbol | Name |
|---|---|
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 |
| ACIN1 | apoptotic chromatin condensation inducer 1 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ANXA1 | annexin A1 |
| ARMC6 | armadillo repeat containing 6 |
| ASB9 | ankyrin repeat and SOCS box containing 9 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BRIX1 | BRX1, biogenesis of ribosomes |
| C16ORF59 | chromosome 16 open reading frame 59 |
| CAPN15 | calpain 15 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CCDC88C | coiled-coil domain containing 88C |
| CENPC | centromere protein C |
| CENPJ | centromere protein J |
| CEP97 | centrosomal protein 97kDa |
| CHMP7 | charged multivesicular body protein 7 |
| CHUK | conserved helix-loop-helix ubiquitous kinase |
| CNPY3 | canopy FGF signaling regulator 3 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| EFCAB2 | EF-hand calcium binding domain 2 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 |
| ENDOG | endonuclease G |
| FLT4 | fms-related tyrosine kinase 4 |
| FOXJ2 | forkhead box J2 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 |
| GOLGA3 | golgin A3 |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| HEATR3 | HEAT repeat containing 3 |
| HMOX1 | heme oxygenase 1 |
| HYAL2 | hyaluronoglucosaminidase 2 |
| IFRD1 | interferon-related developmental regulator 1 |
| INPPL1 | inositol polyphosphate phosphatase-like 1 |
| IRX4 | iroquois homeobox 4 |
| ITPKC | inositol-trisphosphate 3-kinase C |
| KCTD15 | potassium channel tetramerization domain containing 15 |
| KIAA0232 | KIAA0232 |
| MAMLD1 | mastermind-like domain containing 1 |
| MBD5 | methyl-CpG binding domain protein 5 |
| MCMBP | minichromosome maintenance complex binding protein |
| MIR22HG | MIR22 host gene |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MPP6 | membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NDUFAF4 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 |
| NME6 | NME/NM23 nucleoside diphosphate kinase 6 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NT5C | 5', 3'-nucleotidase, cytosolic |
| NUPL2 | nucleoporin like 2 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| POLH | polymerase (DNA directed), eta |
| POU2F1 | POU class 2 homeobox 1 |
| PPIP5K2 | diphosphoinositol pentakisphosphate kinase 2 |
| PRKX | protein kinase, X-linked |
| PROCR | protein C receptor, endothelial |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PRR3 | proline rich 3 |
| RABL6 | RAB, member RAS oncogene family-like 6 |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RBM42 | RNA binding motif protein 42 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF25 | ring finger protein 25 |
| RNF31 | ring finger protein 31 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| SFXN1 | sideroflexin 1 |
| SLC25A32 | solute carrier family 25 (mitochondrial folate carrier), member 32 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SNIP1 | Smad nuclear interacting protein 1 |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| SNX16 | sorting nexin 16 |
| SOWAHC | sosondowah ankyrin repeat domain family member C |
| SPATA2L | spermatogenesis associated 2-like |
| TESK2 | testis-specific kinase 2 |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| THAP7 | THAP domain containing 7 |
| THUMPD2 | THUMP domain containing 2 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM104 | transmembrane protein 104 |
| TMEM51 | transmembrane protein 51 |
| TOE1 | target of EGR1, member 1 (nuclear) |
| TPCN1 | two pore segment channel 1 |
| TRIP10 | thyroid hormone receptor interactor 10 |
| TRMT13 | tRNA methyltransferase 13 homolog (S. cerevisiae) |
| TSSC4 | tumor suppressing subtransferable candidate 4 |
| USP18 | ubiquitin specific peptidase 18 |
| WDR13 | WD repeat domain 13 |
| XKR8 | XK, Kell blood group complex subunit-related family, member 8 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZNF552 | zinc finger protein 552 |
| ZNF767P | zinc finger family member 767, pseudogene |
