| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the sirolimus-6940 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD2 | abhydrolase domain containing 2 |
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ACTA1 | actin, alpha 1, skeletal muscle |
| ADD2 | adducin 2 (beta) |
| ALOX15 | arachidonate 15-lipoxygenase |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ASTN2 | astrotactin 2 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta |
| CCNG2 | cyclin G2 |
| CDKL1 | cyclin-dependent kinase-like 1 (CDC2-related kinase) |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CPE | carboxypeptidase E |
| CRLF1 | cytokine receptor-like factor 1 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DFNB31 | deafness, autosomal recessive 31 |
| DSTYK | dual serine/threonine and tyrosine protein kinase |
| DUSP9 | dual specificity phosphatase 9 |
| DXO | decapping exoribonuclease |
| EDNRA | endothelin receptor type A |
| ELL2 | elongation factor, RNA polymerase II, 2 |
| EMP3 | epithelial membrane protein 3 |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FCMR | Fc fragment of IgM receptor |
| GLI3 | GLI family zinc finger 3 |
| HBP1 | HMG-box transcription factor 1 |
| HBS1L | HBS1-like translational GTPase |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2BJ | histone cluster 1, H2bj |
| IDS | iduronate 2-sulfatase |
| INPP5K | inositol polyphosphate-5-phosphatase K |
| IQCE | IQ motif containing E |
| JMJD4 | jumonji domain containing 4 |
| KCNK15 | potassium channel, two pore domain subfamily K, member 15 |
| KIAA1109 | KIAA1109 |
| LBX1 | ladybird homeobox 1 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| LUZP1 | leucine zipper protein 1 |
| LUZP4 | leucine zipper protein 4 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MAP2K7 | mitogen-activated protein kinase kinase 7 |
| MAPK11 | mitogen-activated protein kinase 11 |
| MOG | myelin oligodendrocyte glycoprotein |
| MST1L | macrophage stimulating 1-like |
| MYOF | myoferlin |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| PELI1 | pellino E3 ubiquitin protein ligase 1 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PLIN2 | perilipin 2 |
| POLL | polymerase (DNA directed), lambda |
| RBM12B-AS1 | RBM12B antisense RNA 1 |
| RER1 | retention in endoplasmic reticulum sorting receptor 1 |
| RGS10 | regulator of G-protein signaling 10 |
| RPLP2 | ribosomal protein, large, P2 |
| SCARB1 | scavenger receptor class B, member 1 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SIK1 | salt-inducible kinase 1 |
| SIVA1 | SIVA1, apoptosis-inducing factor |
| SIX2 | SIX homeobox 2 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 |
| SLC41A3 | solute carrier family 41, member 3 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) |
| SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 |
| STIM1 | stromal interaction molecule 1 |
| STOML1 | stomatin (EPB72)-like 1 |
| STX7 | syntaxin 7 |
| TBRG4 | transforming growth factor beta regulator 4 |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| THAP3 | THAP domain containing, apoptosis associated protein 3 |
| TK2 | thymidine kinase 2, mitochondrial |
| TMC7 | transmembrane channel-like 7 |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 |
| TMEM231 | transmembrane protein 231 |
| TMEM63A | transmembrane protein 63A |
| TUBA3C | tubulin, alpha 3c |
| TXNIP | thioredoxin interacting protein |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| VPS9D1 | VPS9 domain containing 1 |
| WDR61 | WD repeat domain 61 |
| WIZ | widely interspaced zinc finger motifs |
| YLPM1 | YLP motif containing 1 |
| ZFP69B | ZFP69 zinc finger protein B |
| ZNF302 | zinc finger protein 302 |
| ZNF45 | zinc finger protein 45 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ACIN1 | apoptotic chromatin condensation inducer 1 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| AP3M2 | adaptor-related protein complex 3, mu 2 subunit |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 |
| ASB9 | ankyrin repeat and SOCS box containing 9 |
| ATAD3A | ATPase family, AAA domain containing 3A |
| ATF4 | activating transcription factor 4 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BBS7 | Bardet-Biedl syndrome 7 |
| C10ORF88 | chromosome 10 open reading frame 88 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CDKN2AIP | CDKN2A interacting protein |
| CENPT | centromere protein T |
| CEP97 | centrosomal protein 97kDa |
| CHUK | conserved helix-loop-helix ubiquitous kinase |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| COCH | cochlin |
| CRY1 | cryptochrome circadian clock 1 |
| CTNNBL1 | catenin, beta like 1 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 |
| DDA1 | DET1 and DDB1 associated 1 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DEAF1 | DEAF1 transcription factor |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DVL1 | dishevelled segment polarity protein 1 |
| EHD3 | EH-domain containing 3 |
| FAM216A | family with sequence similarity 216, member A |
| FAM53B | family with sequence similarity 53, member B |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 |
| FLT4 | fms-related tyrosine kinase 4 |
| FXN | frataxin |
| GALE | UDP-galactose-4-epimerase |
| GNL2 | guanine nucleotide binding protein-like 2 (nucleolar) |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| GTF2H2B | general transcription factor IIH, polypeptide 2B (pseudogene) |
| HEATR3 | HEAT repeat containing 3 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HOXC13 | homeobox C13 |
| IRF9 | interferon regulatory factor 9 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KLHL2 | kelch-like family member 2 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LINS | lines homolog (Drosophila) |
| LRP5 | low density lipoprotein receptor-related protein 5 |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
| MANEA | mannosidase, endo-alpha |
| MAP7D1 | MAP7 domain containing 1 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MED22 | mediator complex subunit 22 |
| MED24 | mediator complex subunit 24 |
| METTL2B | methyltransferase like 2B |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MICALL2 | MICAL-like 2 |
| MIR22HG | MIR22 host gene |
| MORC3 | MORC family CW-type zinc finger 3 |
| MOSPD3 | motile sperm domain containing 3 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NECAP1 | NECAP endocytosis associated 1 |
| ODF2 | outer dense fiber of sperm tails 2 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PIBF1 | progesterone immunomodulatory binding factor 1 |
| PIGA | phosphatidylinositol glycan anchor biosynthesis, class A |
| POR | P450 (cytochrome) oxidoreductase |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RNF111 | ring finger protein 111 |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| SLMO2 | slowmo homolog 2 (Drosophila) |
| SMAD7 | SMAD family member 7 |
| SNUPN | snurportin 1 |
| SOAT1 | sterol O-acyltransferase 1 |
| SPAG1 | sperm associated antigen 1 |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TAF1A | TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa |
| TEX264 | testis expressed 264 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) |
| TMEM110 | transmembrane protein 110 |
| TMEM115 | transmembrane protein 115 |
| TMEM254 | transmembrane protein 254 |
| TMEM39B | transmembrane protein 39B |
| TMEM57 | transmembrane protein 57 |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 |
| TPTE | transmembrane phosphatase with tensin homology |
| TSPAN14 | tetraspanin 14 |
| TSSC4 | tumor suppressing subtransferable candidate 4 |
| TUBA4A | tubulin, alpha 4a |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| USP6NL | USP6 N-terminal like |
| VASH2 | vasohibin 2 |
| WRN | Werner syndrome, RecQ helicase-like |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZNF324 | zinc finger protein 324 |
| ZNF665 | zinc finger protein 665 |
| ZNF767P | zinc finger family member 767, pseudogene |
