| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the sirolimus-6958 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ADAM19 | ADAM metallopeptidase domain 19 |
| ADCK3 | aarF domain containing kinase 3 |
| ADCY9 | adenylate cyclase 9 |
| AMH | anti-Mullerian hormone |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha |
| ATP9A | ATPase, class II, type 9A |
| ATP9B | ATPase, class II, type 9B |
| AZI2 | 5-azacytidine induced 2 |
| B9D1 | B9 protein domain 1 |
| BEX4 | brain expressed, X-linked 4 |
| C2ORF68 | chromosome 2 open reading frame 68 |
| CADM3 | cell adhesion molecule 3 |
| CASP9 | caspase 9, apoptosis-related cysteine peptidase |
| CBX7 | chromobox homolog 7 |
| CC2D1A | coiled-coil and C2 domain containing 1A |
| CCDC87 | coiled-coil domain containing 87 |
| CCNG2 | cyclin G2 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CLDN15 | claudin 15 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CNTFR | ciliary neurotrophic factor receptor |
| CSTA | cystatin A (stefin A) |
| CYHR1 | cysteine/histidine-rich 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| EDNRA | endothelin receptor type A |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) |
| EMID1 | EMI domain containing 1 |
| EML2 | echinoderm microtubule associated protein like 2 |
| EXOC7 | exocyst complex component 7 |
| FAM114A2 | family with sequence similarity 114, member A2 |
| FAM63A | family with sequence similarity 63, member A |
| FAM86C1 | family with sequence similarity 86, member C1 |
| GAB2 | GRB2-associated binding protein 2 |
| GJB3 | gap junction protein, beta 3, 31kDa |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide |
| GPC3 | glypican 3 |
| GSAP | gamma-secretase activating protein |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HBP1 | HMG-box transcription factor 1 |
| HEG1 | heart development protein with EGF-like domains 1 |
| IFT140 | intraflagellar transport 140 |
| IFT27 | intraflagellar transport 27 |
| INHBA | inhibin, beta A |
| INPP5K | inositol polyphosphate-5-phosphatase K |
| KCNK15 | potassium channel, two pore domain subfamily K, member 15 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| KLHL24 | kelch-like family member 24 |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| LRRC23 | leucine rich repeat containing 23 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MB | myoglobin |
| MED25 | mediator complex subunit 25 |
| MYOF | myoferlin |
| NDOR1 | NADPH dependent diflavin oxidoreductase 1 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NFRKB | nuclear factor related to kappaB binding protein |
| NFYA | nuclear transcription factor Y, alpha |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| NXT2 | nuclear transport factor 2-like export factor 2 |
| OSBPL10 | oxysterol binding protein-like 10 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PAPOLA | poly(A) polymerase alpha |
| PARD6B | par-6 family cell polarity regulator beta |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PLD2 | phospholipase D2 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PTRF | polymerase I and transcript release factor |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| RNF19B | ring finger protein 19B |
| RNMT | RNA (guanine-7-) methyltransferase |
| SECTM1 | secreted and transmembrane 1 |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
| SIK1 | salt-inducible kinase 1 |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TRAPPC13 | trafficking protein particle complex 13 |
| TXNIP | thioredoxin interacting protein |
| WSB1 | WD repeat and SOCS box containing 1 |
| YLPM1 | YLP motif containing 1 |
| ZFPL1 | zinc finger protein-like 1 |
| ZNF45 | zinc finger protein 45 |
| Symbol | Name |
|---|---|
| ADCY6 | adenylate cyclase 6 |
| AEN | apoptosis enhancing nuclease |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ARC | activity-regulated cytoskeleton-associated protein |
| ASB6 | ankyrin repeat and SOCS box containing 6 |
| ASB7 | ankyrin repeat and SOCS box containing 7 |
| ASB9 | ankyrin repeat and SOCS box containing 9 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| AVPI1 | arginine vasopressin-induced 1 |
| BACE1 | beta-site APP-cleaving enzyme 1 |
| BCORL1 | BCL6 corepressor-like 1 |
| BRMS1 | breast cancer metastasis suppressor 1 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C2CD2 | C2 calcium-dependent domain containing 2 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CAPN15 | calpain 15 |
| CARD8 | caspase recruitment domain family, member 8 |
| CCDC9 | coiled-coil domain containing 9 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CEP72 | centrosomal protein 72kDa |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLEC16A | C-type lectin domain family 16, member A |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CPTP | ceramide-1-phosphate transfer protein |
| CRY2 | cryptochrome circadian clock 2 |
| CXORF21 | chromosome X open reading frame 21 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DAGLA | diacylglycerol lipase, alpha |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| EFHD2 | EF-hand domain family, member D2 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| EIF5 | eukaryotic translation initiation factor 5 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM131A | family with sequence similarity 131, member A |
| FASTKD5 | FAST kinase domains 5 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GAMT | guanidinoacetate N-methyltransferase |
| GCC1 | GRIP and coiled-coil domain containing 1 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 |
| GLCE | glucuronic acid epimerase |
| GMIP | GEM interacting protein |
| HIST1H2BN | histone cluster 1, H2bn |
| IFNGR2 | interferon gamma receptor 2 (interferon gamma transducer 1) |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IRF6 | interferon regulatory factor 6 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| MAK16 | MAK16 homolog (S. cerevisiae) |
| MAN2C1 | mannosidase, alpha, class 2C, member 1 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MRPL52 | mitochondrial ribosomal protein L52 |
| MTERF1 | mitochondrial transcription termination factor 1 |
| MTRF1 | mitochondrial translational release factor 1 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon |
| NOP2 | NOP2 nucleolar protein |
| OLFML3 | olfactomedin-like 3 |
| PDE12 | phosphodiesterase 12 |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PER3 | period circadian clock 3 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| POLL | polymerase (DNA directed), lambda |
| PPAN | peter pan homolog (Drosophila) |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) |
| PRMT7 | protein arginine methyltransferase 7 |
| RAB3A | RAB3A, member RAS oncogene family |
| RCOR3 | REST corepressor 3 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF2 | ring finger protein 2 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| S100A4 | S100 calcium binding protein A4 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SAV1 | salvador family WW domain containing protein 1 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 |
| TCTN2 | tectonic family member 2 |
| TET3 | tet methylcytosine dioxygenase 3 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM120B | transmembrane protein 120B |
| TMEM212 | transmembrane protein 212 |
| TOE1 | target of EGR1, member 1 (nuclear) |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| USP18 | ubiquitin specific peptidase 18 |
| UTP20 | UTP20, small subunit (SSU) processome component, homolog (yeast) |
| ZNF180 | zinc finger protein 180 |
| ZNF219 | zinc finger protein 219 |
| ZNF668 | zinc finger protein 668 |
| ZNF767P | zinc finger family member 767, pseudogene |
| ZNF787 | zinc finger protein 787 |
