| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the sirolimus-6981 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACVR2B | activin A receptor, type IIB |
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| AKAP7 | A kinase (PRKA) anchor protein 7 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| AMPD3 | adenosine monophosphate deaminase 3 |
| AP2A2 | adaptor-related protein complex 2, alpha 2 subunit |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| ASTN2 | astrotactin 2 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CCDC71 | coiled-coil domain containing 71 |
| CCDC87 | coiled-coil domain containing 87 |
| CCNG2 | cyclin G2 |
| CCPG1 | cell cycle progression 1 |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CDC25A | cell division cycle 25A |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| COL4A2 | collagen, type IV, alpha 2 |
| CPNE7 | copine VII |
| CYLD | cylindromatosis (turban tumor syndrome) |
| CYP39A1 | cytochrome P450, family 39, subfamily A, polypeptide 1 |
| DBN1 | drebrin 1 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 |
| EN1 | engrailed homeobox 1 |
| ENO2 | enolase 2 (gamma, neuronal) |
| EPHA1 | EPH receptor A1 |
| FCRL2 | Fc receptor-like 2 |
| FECH | ferrochelatase |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| FHL1 | four and a half LIM domains 1 |
| GSAP | gamma-secretase activating protein |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HFE | hemochromatosis |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HIST1H4A | histone cluster 1, H4a |
| IFT54 | intraflagellar transport 54 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| IL11 | interleukin 11 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KIAA0355 | KIAA0355 |
| KIFC3 | kinesin family member C3 |
| KLHL24 | kelch-like family member 24 |
| LDHB | lactate dehydrogenase B |
| LHX1 | LIM homeobox 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAPT | microtubule-associated protein tau |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 |
| MED9 | mediator complex subunit 9 |
| MFAP2 | microfibrillar-associated protein 2 |
| MXD4 | MAX dimerization protein 4 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NRF1 | nuclear respiratory factor 1 |
| NUDT13 | nudix (nucleoside diphosphate linked moiety X)-type motif 13 |
| OCA2 | oculocutaneous albinism II |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCDHB3 | protocadherin beta 3 |
| PDE4C | phosphodiesterase 4C, cAMP-specific |
| PFKFB2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PQBP1 | polyglutamine binding protein 1 |
| PROX1 | prospero homeobox 1 |
| PRRG2 | proline rich Gla (G-carboxyglutamic acid) 2 |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| RCBTB1 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 |
| RCN3 | reticulocalbin 3, EF-hand calcium binding domain |
| RECQL5 | RecQ protein-like 5 |
| RIN2 | Ras and Rab interactor 2 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 |
| SFTPB | surfactant protein B |
| SIGLEC6 | sialic acid binding Ig-like lectin 6 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SSPN | sarcospan |
| SYNJ2 | synaptojanin 2 |
| TCF12 | transcription factor 12 |
| TCP10L | t-complex 10-like |
| TDRD1 | tudor domain containing 1 |
| TMC5 | transmembrane channel-like 5 |
| TMEM53 | transmembrane protein 53 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TXNIP | thioredoxin interacting protein |
| UNC5B | unc-5 homolog B (C. elegans) |
| ZNF16 | zinc finger protein 16 |
| ZNF384 | zinc finger protein 384 |
| ZNF419 | zinc finger protein 419 |
| ZNF549 | zinc finger protein 549 |
| ZNF747 | zinc finger protein 747 |
| ZNF783 | zinc finger family member 783 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
| ANKRD10 | ankyrin repeat domain 10 |
| ARFIP2 | ADP-ribosylation factor interacting protein 2 |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 |
| ATAD3A | ATPase family, AAA domain containing 3A |
| ATAD5 | ATPase family, AAA domain containing 5 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C21ORF91 | chromosome 21 open reading frame 91 |
| C5ORF28 | chromosome 5 open reading frame 28 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CBX4 | chromobox homolog 4 |
| CCDC86 | coiled-coil domain containing 86 |
| CCNJ | cyclin J |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) |
| CENPJ | centromere protein J |
| CEP72 | centrosomal protein 72kDa |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CHUK | conserved helix-loop-helix ubiquitous kinase |
| COG4 | component of oligomeric golgi complex 4 |
| CRY1 | cryptochrome circadian clock 1 |
| CTSK | cathepsin K |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 |
| DYNC1LI1 | dynein, cytoplasmic 1, light intermediate chain 1 |
| EPPK1 | epiplakin 1 |
| ERO1L | ERO1-like (S. cerevisiae) |
| FOXJ2 | forkhead box J2 |
| GAB2 | GRB2-associated binding protein 2 |
| GAN | gigaxonin |
| HCFC2 | host cell factor C2 |
| HOMER1 | homer scaffolding protein 1 |
| ICK | intestinal cell (MAK-like) kinase |
| IFRD1 | interferon-related developmental regulator 1 |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| INPPL1 | inositol polyphosphate phosphatase-like 1 |
| JMJD4 | jumonji domain containing 4 |
| KATNBL1 | katanin p80 subunit B-like 1 |
| KIAA0753 | KIAA0753 |
| KIAA0895 | KIAA0895 |
| LMNB2 | lamin B2 |
| LOXL1 | lysyl oxidase-like 1 |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| MAN2B2 | mannosidase, alpha, class 2B, member 2 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MGC12488 | |
| MIR22HG | MIR22 host gene |
| MRPL52 | mitochondrial ribosomal protein L52 |
| MSX1 | msh homeobox 1 |
| MUM1 | melanoma associated antigen (mutated) 1 |
| NBEAL2 | neurobeachin-like 2 |
| NCAM2 | neural cell adhesion molecule 2 |
| NDUFAF4 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 |
| NOTCH1 | notch 1 |
| OTUD3 | OTU deubiquitinase 3 |
| PARD6A | par-6 family cell polarity regulator alpha |
| PGP | phosphoglycolate phosphatase |
| POLD3 | polymerase (DNA-directed), delta 3, accessory subunit |
| PROCR | protein C receptor, endothelial |
| RAB11FIP2 | RAB11 family interacting protein 2 (class I) |
| RAI14 | retinoic acid induced 14 |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RINT1 | RAD50 interactor 1 |
| RNF31 | ring finger protein 31 |
| RP2 | retinitis pigmentosa 2 (X-linked recessive) |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SAMHD1 | SAM domain and HD domain 1 |
| SAV1 | salvador family WW domain containing protein 1 |
| SCAMP3 | secretory carrier membrane protein 3 |
| SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain |
| SLC25A20 | solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 |
| SLC25A44 | solute carrier family 25, member 44 |
| SLC35F2 | solute carrier family 35, member F2 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 |
| SPHK1 | sphingosine kinase 1 |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TCTN2 | tectonic family member 2 |
| TESK1 | testis-specific kinase 1 |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| THAP4 | THAP domain containing 4 |
| TPST1 | tyrosylprotein sulfotransferase 1 |
| TRIP10 | thyroid hormone receptor interactor 10 |
| TSPAN14 | tetraspanin 14 |
| TSSC4 | tumor suppressing subtransferable candidate 4 |
| TYW1 | tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) |
| UNC119 | unc-119 homolog (C. elegans) |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZDHHC13 | zinc finger, DHHC-type containing 13 |
| ZMYM1 | zinc finger, MYM-type 1 |
| ZNF107 | zinc finger protein 107 |
| ZNF350 | zinc finger protein 350 |
| ZNF408 | zinc finger protein 408 |
