| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the sirolimus-921 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADGRE2 | adhesion G protein-coupled receptor E2 |
| AHNAK2 | AHNAK nucleoprotein 2 |
| AKAP13 | A kinase (PRKA) anchor protein 13 |
| AKAP7 | A kinase (PRKA) anchor protein 7 |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| APOE | apolipoprotein E |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) |
| ARL4C | ADP-ribosylation factor-like 4C |
| ASB1 | ankyrin repeat and SOCS box containing 1 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| CA4 | carbonic anhydrase IV |
| CALD1 | caldesmon 1 |
| CCDC132 | coiled-coil domain containing 132 |
| CD52 | CD52 molecule |
| CD96 | CD96 molecule |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CENPQ | centromere protein Q |
| COL1A1 | collagen, type I, alpha 1 |
| COL4A5 | collagen, type IV, alpha 5 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CTSF | cathepsin F |
| CTTN | cortactin |
| CUL9 | cullin 9 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DBT | dihydrolipoamide branched chain transacylase E2 |
| DUSP4 | dual specificity phosphatase 4 |
| DZIP3 | DAZ interacting zinc finger protein 3 |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B |
| EPHB2 | EPH receptor B2 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| EXTL3 | exostosin-like glycosyltransferase 3 |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GPATCH2L | G patch domain containing 2-like |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| GSTA3 | glutathione S-transferase alpha 3 |
| HFE | hemochromatosis |
| HSPB11 | heat shock protein family B (small), member 11 |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
| HTR7 | 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase |
| INO80B | INO80 complex subunit B |
| KIF25-AS1 | KIF25 antisense RNA 1 |
| KLF13 | Kruppel-like factor 13 |
| KLHL23 | kelch-like family member 23 |
| KLHL24 | kelch-like family member 24 |
| KLHL28 | kelch-like family member 28 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 |
| LOC644450 | uncharacterized LOC644450 |
| LPXN | leupaxin |
| MEP1B | meprin A, beta |
| MST1 | macrophage stimulating 1 |
| MXD4 | MAX dimerization protein 4 |
| MYLK | myosin light chain kinase |
| NEK9 | NIMA-related kinase 9 |
| NPFFR1 | neuropeptide FF receptor 1 |
| PADI3 | peptidyl arginine deiminase, type III |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PPARD | peroxisome proliferator-activated receptor delta |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta |
| PRDX2 | peroxiredoxin 2 |
| PRKD3 | protein kinase D3 |
| PSMB1 | proteasome (prosome, macropain) subunit, beta type, 1 |
| PTPRF | protein tyrosine phosphatase, receptor type, F |
| RECQL5 | RecQ protein-like 5 |
| RGS6 | regulator of G-protein signaling 6 |
| RNF208 | ring finger protein 208 |
| RPL10 | ribosomal protein L10 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 |
| RTN2 | reticulon 2 |
| SC5D | sterol-C5-desaturase |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SIK1 | salt-inducible kinase 1 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC25A16 | solute carrier family 25 (mitochondrial carrier), member 16 |
| SPATA5L1 | spermatogenesis associated 5-like 1 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SPON2 | spondin 2, extracellular matrix protein |
| SUGP1 | SURP and G patch domain containing 1 |
| SURF1 | surfeit 1 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) |
| TDRD12 | tudor domain containing 12 |
| THBS3 | thrombospondin 3 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
| TMEM209 | transmembrane protein 209 |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| TSR3 | TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) |
| TUBA3C | tubulin, alpha 3c |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) |
| WDR1 | WD repeat domain 1 |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| ZNF451 | zinc finger protein 451 |
| ZNF783 | zinc finger family member 783 |
| Symbol | Name |
|---|---|
| ADAM15 | ADAM metallopeptidase domain 15 |
| ARHGAP11A | Rho GTPase activating protein 11A |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| AVPI1 | arginine vasopressin-induced 1 |
| BBS7 | Bardet-Biedl syndrome 7 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| BYSL | bystin-like |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CCDC85C | coiled-coil domain containing 85C |
| CDK20 | cyclin-dependent kinase 20 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CORO1A | coronin, actin binding protein, 1A |
| DDA1 | DET1 and DDB1 associated 1 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| EAF2 | ELL associated factor 2 |
| EMC7 | ER membrane protein complex subunit 7 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FJX1 | four jointed box 1 (Drosophila) |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GPALPP1 | GPALPP motifs containing 1 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HDAC4 | histone deacetylase 4 |
| HIST1H2AM | histone cluster 1, H2am |
| HMHA1 | histocompatibility (minor) HA-1 |
| HSPA2 | heat shock 70kDa protein 2 |
| HYI | hydroxypyruvate isomerase (putative) |
| IL17RA | interleukin 17 receptor A |
| IMPA1 | inositol(myo)-1(or 4)-monophosphatase 1 |
| KATNBL1 | katanin p80 subunit B-like 1 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KRT15 | keratin 15, type I |
| L2HGDH | L-2-hydroxyglutarate dehydrogenase |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MAPK12 | mitogen-activated protein kinase 12 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| METTL8 | methyltransferase like 8 |
| MIR22HG | MIR22 host gene |
| MMP9 | matrix metallopeptidase 9 |
| MORC3 | MORC family CW-type zinc finger 3 |
| MPP6 | membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MTA2 | metastasis associated 1 family, member 2 |
| NAG18 | NAG18 mRNA |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NUS1P3 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3 |
| P3H1 | prolyl 3-hydroxylase 1 |
| PCBP4 | poly(rC) binding protein 4 |
| PCDHB13 | protocadherin beta 13 |
| PDGFRL | platelet-derived growth factor receptor-like |
| PDZRN3 | PDZ domain containing ring finger 3 |
| PGPEP1 | pyroglutamyl-peptidase I |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLA2G3 | phospholipase A2, group III |
| PLD2 | phospholipase D2 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| POLH | polymerase (DNA directed), eta |
| PPAN | peter pan homolog (Drosophila) |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| RAB33B | RAB33B, member RAS oncogene family |
| RPL23AP7 | ribosomal protein L23a pseudogene 7 |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| SAMD9 | sterile alpha motif domain containing 9 |
| SCAND1 | SCAN domain containing 1 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SH2B3 | SH2B adaptor protein 3 |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SRRD | SRR1 domain containing |
| STIM1 | stromal interaction molecule 1 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| SYBU | syntabulin (syntaxin-interacting) |
| SYT17 | synaptotagmin XVII |
| TMEM51 | transmembrane protein 51 |
| TMPRSS3 | transmembrane protease, serine 3 |
| TPST1 | tyrosylprotein sulfotransferase 1 |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| UBQLN4 | ubiquilin 4 |
| USB1 | U6 snRNA biogenesis 1 |
| UTP20 | UTP20, small subunit (SSU) processome component, homolog (yeast) |
| WDR4 | WD repeat domain 4 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZCCHC10 | zinc finger, CCHC domain containing 10 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF268 | zinc finger protein 268 |
| ZNF34 | zinc finger protein 34 |
| ZNF35 | zinc finger protein 35 |
| ZNF552 | zinc finger protein 552 |
| ZNF76 | zinc finger protein 76 |
