| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the sirolimus-987 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ADRA1D | adrenoceptor alpha 1D |
| AIPL1 | aryl hydrocarbon receptor interacting protein-like 1 |
| AOAH | acyloxyacyl hydrolase (neutrophil) |
| APOL2 | apolipoprotein L, 2 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) |
| ATP11A | ATPase, class VI, type 11A |
| ATPAF2 | ATP synthase mitochondrial F1 complex assembly factor 2 |
| ATXN3 | ataxin 3 |
| BIN1 | bridging integrator 1 |
| CASS4 | Cas scaffolding protein family member 4 |
| CCDC85B | coiled-coil domain containing 85B |
| CD6 | CD6 molecule |
| CD82 | CD82 molecule |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CDHR2 | cadherin-related family member 2 |
| CNN1 | calponin 1, basic, smooth muscle |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 |
| COL1A1 | collagen, type I, alpha 1 |
| COL9A3 | collagen, type IX, alpha 3 |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 |
| DBF4B | DBF4 zinc finger B |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 |
| DLX5 | distal-less homeobox 5 |
| EGR1 | early growth response 1 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FABP6 | fatty acid binding protein 6, ileal |
| FAM13C | family with sequence similarity 13, member C |
| FAM155A | family with sequence similarity 155, member A |
| FAM214B | family with sequence similarity 214, member B |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| HABP4 | hyaluronan binding protein 4 |
| HEG1 | heart development protein with EGF-like domains 1 |
| HIST1H2AI | histone cluster 1, H2ai |
| HLA-F | major histocompatibility complex, class I, F |
| HRG | histidine-rich glycoprotein |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| HTR7 | 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled |
| IBSP | integrin-binding sialoprotein |
| IGKV3-20 | immunoglobulin kappa variable 3-20 |
| JAG1 | jagged 1 |
| KATNB1 | katanin p80 (WD repeat containing) subunit B 1 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KLHL22 | kelch-like family member 22 |
| KLHL24 | kelch-like family member 24 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LOC100129648 | uncharacterized LOC100129648 |
| MAP2K7 | mitogen-activated protein kinase kinase 7 |
| MAPK10 | mitogen-activated protein kinase 10 |
| MED15 | mediator complex subunit 15 |
| MMP1 | matrix metallopeptidase 1 |
| MTSS1L | metastasis suppressor 1-like |
| MVP | major vault protein |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NHLH2 | nescient helix loop helix 2 |
| PARP11 | poly (ADP-ribose) polymerase family, member 11 |
| PCDHB17P | protocadherin beta 17 pseudogene |
| PCNX | pecanex homolog (Drosophila) |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PIGC | phosphatidylinositol glycan anchor biosynthesis, class C |
| PLIN2 | perilipin 2 |
| PPARA | peroxisome proliferator-activated receptor alpha |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| PRLR | prolactin receptor |
| PRPF18 | pre-mRNA processing factor 18 |
| PRSS53 | protease, serine, 53 |
| RGS10 | regulator of G-protein signaling 10 |
| RGS12 | regulator of G-protein signaling 12 |
| RIN2 | Ras and Rab interactor 2 |
| RPL10 | ribosomal protein L10 |
| RPS6KA6 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| RUFY3 | RUN and FYVE domain containing 3 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC25A16 | solute carrier family 25 (mitochondrial carrier), member 16 |
| SPATA1 | spermatogenesis associated 1 |
| SPON2 | spondin 2, extracellular matrix protein |
| SUGP1 | SURP and G patch domain containing 1 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TAOK1 | TAO kinase 1 |
| TIGD6 | tigger transposable element derived 6 |
| TMPRSS4 | transmembrane protease, serine 4 |
| TNS2 | tensin 2 |
| TPP1 | tripeptidyl peptidase I |
| TRIM10 | tripartite motif containing 10 |
| TTLL5 | tubulin tyrosine ligase-like family member 5 |
| TXNIP | thioredoxin interacting protein |
| WIZ | widely interspaced zinc finger motifs |
| ZNF45 | zinc finger protein 45 |
| ZNF639 | zinc finger protein 639 |
| ZNF682 | zinc finger protein 682 |
| ZNF771 | zinc finger protein 771 |
| ZSCAN2 | zinc finger and SCAN domain containing 2 |
| Symbol | Name |
|---|---|
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| AEN | apoptosis enhancing nuclease |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ASB6 | ankyrin repeat and SOCS box containing 6 |
| BBS7 | Bardet-Biedl syndrome 7 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C19ORF24 | chromosome 19 open reading frame 24 |
| C9ORF91 | chromosome 9 open reading frame 91 |
| CCDC86 | coiled-coil domain containing 86 |
| CCNE1 | cyclin E1 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHKB | choline kinase beta |
| CUL1 | cullin 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| EFHD2 | EF-hand domain family, member D2 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| EHD3 | EH-domain containing 3 |
| EOGT | EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase |
| EPS8L2 | EPS8-like 2 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FASTKD5 | FAST kinase domains 5 |
| FOSL1 | FOS-like antigen 1 |
| GLCE | glucuronic acid epimerase |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GNE | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase |
| GNL2 | guanine nucleotide binding protein-like 2 (nucleolar) |
| HAUS6 | HAUS augmin-like complex, subunit 6 |
| HCFC2 | host cell factor C2 |
| HEATR3 | HEAT repeat containing 3 |
| HHEX | hematopoietically expressed homeobox |
| HIRA | histone cell cycle regulator |
| HPS5 | Hermansky-Pudlak syndrome 5 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 |
| IFNGR2 | interferon gamma receptor 2 (interferon gamma transducer 1) |
| IFRD1 | interferon-related developmental regulator 1 |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| KLHL2 | kelch-like family member 2 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LYRM2 | LYR motif containing 2 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 |
| MAPK12 | mitogen-activated protein kinase 12 |
| MDM4 | MDM4, p53 regulator |
| MGAT1 | mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
| MNS1 | meiosis-specific nuclear structural 1 |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein |
| NOTCH1 | notch 1 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| NRBF2 | nuclear receptor binding factor 2 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PDZRN3 | PDZ domain containing ring finger 3 |
| POLH | polymerase (DNA directed), eta |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa |
| PSKH1 | protein serine kinase H1 |
| PSMB10 | proteasome (prosome, macropain) subunit, beta type, 10 |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) |
| RASA2 | RAS p21 protein activator 2 |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RBL1 | retinoblastoma-like 1 |
| RBM38 | RNA binding motif protein 38 |
| RGS19 | regulator of G-protein signaling 19 |
| RNF25 | ring finger protein 25 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
| RP2 | retinitis pigmentosa 2 (X-linked recessive) |
| SARS2 | seryl-tRNA synthetase 2, mitochondrial |
| SCO2 | SCO2 cytochrome c oxidase assembly protein |
| SHARPIN | SHANK-associated RH domain interactor |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SPIDR | scaffolding protein involved in DNA repair |
| SSFA2 | sperm specific antigen 2 |
| STK25 | serine/threonine kinase 25 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) |
| SURF2 | surfeit 2 |
| SUSD4 | sushi domain containing 4 |
| TGDS | TDP-glucose 4,6-dehydratase |
| THOC1 | THO complex 1 |
| THOP1 | thimet oligopeptidase 1 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM183A | transmembrane protein 183A |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TPST1 | tyrosylprotein sulfotransferase 1 |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| UTP20 | UTP20, small subunit (SSU) processome component, homolog (yeast) |
| WDR18 | WD repeat domain 18 |
| WDR76 | WD repeat domain 76 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF408 | zinc finger protein 408 |
| ZNF473 | zinc finger protein 473 |
| ZNF492 | zinc finger protein 492 |
| ZNF721 | zinc finger protein 721 |
| ZNF778 | zinc finger protein 778 |
