| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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194 genes differentially expressed following the sisomicin-2493 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AIM1L | absent in melanoma 1-like |
| APBB1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| BTN2A2 | butyrophilin, subfamily 2, member A2 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CA9 | carbonic anhydrase IX |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CCL22 | chemokine (C-C motif) ligand 22 |
| CD6 | CD6 molecule |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CHD9 | chromodomain helicase DNA binding protein 9 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
| CLCA2 | chloride channel accessory 2 |
| CNPY4 | canopy FGF signaling regulator 4 |
| CTAGE9 | CTAGE family, member 9 |
| DDR1 | discoidin domain receptor tyrosine kinase 1 |
| DLG4 | discs, large homolog 4 (Drosophila) |
| DNASE1L3 | deoxyribonuclease I-like 3 |
| DSG3 | desmoglein 3 |
| DUSP1 | dual specificity phosphatase 1 |
| EMID1 | EMI domain containing 1 |
| EMP1 | epithelial membrane protein 1 |
| FAM46C | family with sequence similarity 46, member C |
| FCMR | Fc fragment of IgM receptor |
| FOXA1 | forkhead box A1 |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 |
| GCH1 | GTP cyclohydrolase 1 |
| GFER | growth factor, augmenter of liver regeneration |
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 |
| GNRH1 | gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) |
| GPR162 | G protein-coupled receptor 162 |
| GPX2 | glutathione peroxidase 2 |
| GRB7 | growth factor receptor-bound protein 7 |
| GRIN1 | glutamate receptor, ionotropic, N-methyl D-aspartate 1 |
| GSK3A | glycogen synthase kinase 3 alpha |
| HES1 | hes family bHLH transcription factor 1 |
| HOXC4 | homeobox C4 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| INHBA | inhibin, beta A |
| IRX4 | iroquois homeobox 4 |
| KLC2 | kinesin light chain 2 |
| KLF12 | Kruppel-like factor 12 |
| KLF3 | Kruppel-like factor 3 (basic) |
| KRT81 | keratin 81, type II |
| KRT9 | keratin 9, type I |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LIF | leukemia inhibitory factor |
| LOC390998 | ribosomal protein L10 pseudogene |
| LPCAT4 | lysophosphatidylcholine acyltransferase 4 |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MAPK7 | mitogen-activated protein kinase 7 |
| MMP3 | matrix metallopeptidase 3 |
| MXD4 | MAX dimerization protein 4 |
| MYL10 | myosin, light chain 10, regulatory |
| MYOM1 | myomesin 1 |
| NEK11 | NIMA-related kinase 11 |
| NEURL1 | neuralized E3 ubiquitin protein ligase 1 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NKX3-2 | NK3 homeobox 2 |
| NLGN1 | neuroligin 1 |
| NRG2 | neuregulin 2 |
| NUP88 | nucleoporin 88kDa |
| OCM2 | oncomodulin 2 |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PEX11A | peroxisomal biogenesis factor 11 alpha |
| PLSCR3 | phospholipid scramblase 3 |
| PML | promyelocytic leukemia |
| PODNL1 | podocan-like 1 |
| POU2F2 | POU class 2 homeobox 2 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RIN2 | Ras and Rab interactor 2 |
| SCN11A | sodium channel, voltage gated, type XI alpha subunit |
| SDHB | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) |
| SFN | stratifin |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SP140 | SP140 nuclear body protein |
| SPIB | Spi-B transcription factor (Spi-1/PU.1 related) |
| SRD5A2 | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) |
| SSH3 | slingshot protein phosphatase 3 |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| SYT13 | synaptotagmin XIII |
| TEF | thyrotrophic embryonic factor |
| TFF2 | trefoil factor 2 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 |
| USF2 | upstream transcription factor 2, c-fos interacting |
| VENTX | VENT homeobox |
| WRAP53 | WD repeat containing, antisense to TP53 |
| ZNF444 | zinc finger protein 444 |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ACPP | acid phosphatase, prostate |
| ADAP2 | ArfGAP with dual PH domains 2 |
| AIPL1 | aryl hydrocarbon receptor interacting protein-like 1 |
| AMDHD2 | amidohydrolase domain containing 2 |
| APOBEC1 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 |
| ARRB1 | arrestin, beta 1 |
| ASGR2 | asialoglycoprotein receptor 2 |
| B9D2 | B9 protein domain 2 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 |
| BPI | bactericidal/permeability-increasing protein |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CD300C | CD300c molecule |
| CD320 | CD320 molecule |
| CES3 | carboxylesterase 3 |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| CYP2W1 | cytochrome P450, family 2, subfamily W, polypeptide 1 |
| DGKG | diacylglycerol kinase, gamma 90kDa |
| DNMBP | dynamin binding protein |
| DOK5 | docking protein 5 |
| DPEP2 | dipeptidase 2 |
| FBXO31 | F-box protein 31 |
| FCGR1A | Fc fragment of IgG, high affinity Ia, receptor (CD64) |
| FKBP5 | FK506 binding protein 5 |
| FOXN2 | forkhead box N2 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GAMT | guanidinoacetate N-methyltransferase |
| GRAMD1B | GRAM domain containing 1B |
| GTF2I | general transcription factor IIi |
| HIRA | histone cell cycle regulator |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HRH2 | histamine receptor H2 |
| IER3IP1 | immediate early response 3 interacting protein 1 |
| IFI6 | interferon, alpha-inducible protein 6 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KLHL28 | kelch-like family member 28 |
| LPPR3 | lipid phosphate phosphatase-related protein type 3 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| LRP5 | low density lipoprotein receptor-related protein 5 |
| LTC4S | leukotriene C4 synthase |
| MAGOHB | mago-nashi homolog B (Drosophila) |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MCPH1 | microcephalin 1 |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial |
| MRAS | muscle RAS oncogene homolog |
| N6AMT1 | N-6 adenine-specific DNA methyltransferase 1 (putative) |
| NCS1 | neuronal calcium sensor 1 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| P2RY1 | purinergic receptor P2Y, G-protein coupled, 1 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PITX2 | paired-like homeodomain 2 |
| PLD3 | phospholipase D family, member 3 |
| PMCH | pro-melanin-concentrating hormone |
| POLL | polymerase (DNA directed), lambda |
| PORCN | porcupine homolog (Drosophila) |
| PTPN4 | protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) |
| PWAR5 | Prader Willi/Angelman region RNA 5 |
| RAB33A | RAB33A, member RAS oncogene family |
| REC8 | REC8 meiotic recombination protein |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RPL10L | ribosomal protein L10-like |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 |
| SLC16A4 | solute carrier family 16, member 4 |
| SLC2A9 | solute carrier family 2 (facilitated glucose transporter), member 9 |
| SLC35F6 | solute carrier family 35, member F6 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SNAI1 | snail family zinc finger 1 |
| TBC1D19 | TBC1 domain family, member 19 |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TMEM110 | transmembrane protein 110 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 |
| TRABD | TraB domain containing |
| TRIM25 | tripartite motif containing 25 |
| TXLNG | taxilin gamma |
| UPB1 | ureidopropionase, beta |
| VNN2 | vanin 2 |
| WDR62 | WD repeat domain 62 |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZNF141 | zinc finger protein 141 |
| ZNF16 | zinc finger protein 16 |
| ZNF552 | zinc finger protein 552 |
| ZNF675 | zinc finger protein 675 |
| ZNF696 | zinc finger protein 696 |
| ZNF770 | zinc finger protein 770 |
| ZNF813 | zinc finger protein 813 |