| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the sisomicin-4014 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC6 | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
| AKAP5 | A kinase (PRKA) anchor protein 5 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| ALPK3 | alpha-kinase 3 |
| APC | adenomatous polyposis coli |
| APOM | apolipoprotein M |
| ARHGAP1 | Rho GTPase activating protein 1 |
| ARHGAP15 | Rho GTPase activating protein 15 |
| ARHGAP26 | Rho GTPase activating protein 26 |
| B3GNTL1 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 |
| BCL2L11 | BCL2-like 11 (apoptosis facilitator) |
| BHMT2 | betaine--homocysteine S-methyltransferase 2 |
| C11ORF1 | chromosome 11 open reading frame 1 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase |
| CBS | cystathionine-beta-synthase |
| CCDC132 | coiled-coil domain containing 132 |
| CDC42 | cell division cycle 42 |
| CEACAM4 | carcinoembryonic antigen-related cell adhesion molecule 4 |
| CLCN4 | chloride channel, voltage-sensitive 4 |
| COBL | cordon-bleu WH2 repeat protein |
| COL16A1 | collagen, type XVI, alpha 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DIO3 | deiodinase, iodothyronine, type III |
| DLC1 | DLC1 Rho GTPase activating protein |
| DLX2 | distal-less homeobox 2 |
| DOCK10 | dedicator of cytokinesis 10 |
| DPF3 | D4, zinc and double PHD fingers, family 3 |
| DTNB | dystrobrevin, beta |
| EGR1 | early growth response 1 |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 |
| EPHA1 | EPH receptor A1 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GLG1 | golgi glycoprotein 1 |
| GRIA3 | glutamate receptor, ionotropic, AMPA 3 |
| GRM7 | glutamate receptor, metabotropic 7 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IL5RA | interleukin 5 receptor, alpha |
| INO80D | INO80 complex subunit D |
| KLF13 | Kruppel-like factor 13 |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LOXL2 | lysyl oxidase-like 2 |
| LRP4 | low density lipoprotein receptor-related protein 4 |
| MARS | methionyl-tRNA synthetase |
| MBD2 | methyl-CpG binding domain protein 2 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MUC2 | mucin 2, oligomeric mucus/gel-forming |
| NEU3 | sialidase 3 (membrane sialidase) |
| NF1 | neurofibromin 1 |
| NPTX1 | neuronal pentraxin I |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PCDH1 | protocadherin 1 |
| PDCD2 | programmed cell death 2 |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PER2 | period circadian clock 2 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PKD2L2 | polycystic kidney disease 2-like 2 |
| POU4F2 | POU class 4 homeobox 2 |
| PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D |
| RAB31 | RAB31, member RAS oncogene family |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RB1 | retinoblastoma 1 |
| REC8 | REC8 meiotic recombination protein |
| RGS14 | regulator of G-protein signaling 14 |
| RHOBTB3 | Rho-related BTB domain containing 3 |
| RNF39 | ring finger protein 39 |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| SAMD4A | sterile alpha motif domain containing 4A |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SDF4 | stromal cell derived factor 4 |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) |
| SIGLEC6 | sialic acid binding Ig-like lectin 6 |
| SIT1 | signaling threshold regulating transmembrane adaptor 1 |
| SLC5A1 | solute carrier family 5 (sodium/glucose cotransporter), member 1 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SLCO1C1 | solute carrier organic anion transporter family, member 1C1 |
| SMAD4 | SMAD family member 4 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SPIDR | scaffolding protein involved in DNA repair |
| TADA2A | transcriptional adaptor 2A |
| TEX13A | testis expressed 13A |
| THBD | thrombomodulin |
| TMEM63A | transmembrane protein 63A |
| TNPO2 | transportin 2 |
| TRMT44 | tRNA methyltransferase 44 homolog (S. cerevisiae) |
| TSPAN1 | tetraspanin 1 |
| TSPAN8 | tetraspanin 8 |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| VARS | valyl-tRNA synthetase |
| WNK1 | WNK lysine deficient protein kinase 1 |
| ZFPL1 | zinc finger protein-like 1 |
| ZNF552 | zinc finger protein 552 |
| Symbol | Name |
|---|---|
| ABCB8 | ATP-binding cassette, sub-family B (MDR/TAP), member 8 |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| ALOX15B | arachidonate 15-lipoxygenase, type B |
| ALPK1 | alpha-kinase 1 |
| ARHGAP22 | Rho GTPase activating protein 22 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| AXIN1 | axin 1 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BFSP1 | beaded filament structural protein 1, filensin |
| BMP15 | bone morphogenetic protein 15 |
| BST1 | bone marrow stromal cell antigen 1 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CA9 | carbonic anhydrase IX |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CASZ1 | castor zinc finger 1 |
| CCNO | cyclin O |
| CD70 | CD70 molecule |
| CENPO | centromere protein O |
| CIDEB | cell death-inducing DFFA-like effector b |
| COG4 | component of oligomeric golgi complex 4 |
| CRMP1 | collapsin response mediator protein 1 |
| CTSK | cathepsin K |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 |
| DBF4B | DBF4 zinc finger B |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DNM3 | dynamin 3 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 |
| EPN1 | epsin 1 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FAM110B | family with sequence similarity 110, member B |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| GJA9 | gap junction protein, alpha 9, 59kDa |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GRM4 | glutamate receptor, metabotropic 4 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H3B | histone cluster 1, H3b |
| HIST1H3C | histone cluster 1, H3c |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ITGB7 | integrin, beta 7 |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KHDRBS2 | KH domain containing, RNA binding, signal transduction associated 2 |
| KLHL28 | kelch-like family member 28 |
| LATS1 | large tumor suppressor kinase 1 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LINC00260 | long intergenic non-protein coding RNA 260 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LRRC15 | leucine rich repeat containing 15 |
| MAP3K7CL | MAP3K7 C-terminal like |
| MMP10 | matrix metallopeptidase 10 |
| MNMIP1 | manchette microtubule inner protein 1 |
| MTSS1L | metastasis suppressor 1-like |
| MYO1F | myosin IF |
| NKX3-2 | NK3 homeobox 2 |
| NOL12 | nucleolar protein 12 |
| PLBD1 | phospholipase B domain containing 1 |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| POLL | polymerase (DNA directed), lambda |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRSS53 | protease, serine, 53 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| S100A3 | S100 calcium binding protein A3 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SECISBP2 | SECIS binding protein 2 |
| SH3GLB2 | SH3-domain GRB2-like endophilin B2 |
| SLAMF7 | SLAM family member 7 |
| SLC18A2 | solute carrier family 18 (vesicular monoamine transporter), member 2 |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC6A9 | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 |
| SND1-IT1 | SND1 intronic transcript 1 |
| STAB2 | stabilin 2 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TAOK1 | TAO kinase 1 |
| TBC1D17 | TBC1 domain family, member 17 |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| VGLL3 | vestigial-like family member 3 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF222 | zinc finger protein 222 |
| ZNF268 | zinc finger protein 268 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF480 | zinc finger protein 480 |
| ZNF667 | zinc finger protein 667 |
| ZXDB | zinc finger, X-linked, duplicated B |