sisomicin-4014 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the sisomicin-4014 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
AKAP5 A kinase (PRKA) anchor protein 5
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALPK3 alpha-kinase 3
APC adenomatous polyposis coli
APOM apolipoprotein M
ARHGAP1 Rho GTPase activating protein 1
ARHGAP15 Rho GTPase activating protein 15
ARHGAP26 Rho GTPase activating protein 26
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BHMT2 betaine--homocysteine S-methyltransferase 2
C11ORF1 chromosome 11 open reading frame 1
C1ORF54 chromosome 1 open reading frame 54
CA5B carbonic anhydrase VB, mitochondrial
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CASP8 caspase 8, apoptosis-related cysteine peptidase
CBS cystathionine-beta-synthase
CCDC132 coiled-coil domain containing 132
CDC42 cell division cycle 42
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CLCN4 chloride channel, voltage-sensitive 4
COBL cordon-bleu WH2 repeat protein
COL16A1 collagen, type XVI, alpha 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
DGKE diacylglycerol kinase, epsilon 64kDa
DIO3 deiodinase, iodothyronine, type III
DLC1 DLC1 Rho GTPase activating protein
DLX2 distal-less homeobox 2
DOCK10 dedicator of cytokinesis 10
DPF3 D4, zinc and double PHD fingers, family 3
DTNB dystrobrevin, beta
EGR1 early growth response 1
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
EPHA1 EPH receptor A1
EXD3 exonuclease 3'-5' domain containing 3
GAL3ST4 galactose-3-O-sulfotransferase 4
GLG1 golgi glycoprotein 1
GRIA3 glutamate receptor, ionotropic, AMPA 3
GRM7 glutamate receptor, metabotropic 7
IDI2-AS1 IDI2 antisense RNA 1
IL5RA interleukin 5 receptor, alpha
INO80D INO80 complex subunit D
KLF13 Kruppel-like factor 13
LINC00115 long intergenic non-protein coding RNA 115
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LOXL2 lysyl oxidase-like 2
LRP4 low density lipoprotein receptor-related protein 4
MARS methionyl-tRNA synthetase
MBD2 methyl-CpG binding domain protein 2
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MUC2 mucin 2, oligomeric mucus/gel-forming
NEU3 sialidase 3 (membrane sialidase)
NF1 neurofibromin 1
NPTX1 neuronal pentraxin I
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PCDH1 protocadherin 1
PDCD2 programmed cell death 2
PDE2A phosphodiesterase 2A, cGMP-stimulated
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PER2 period circadian clock 2
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PKD2L2 polycystic kidney disease 2-like 2
POU4F2 POU class 4 homeobox 2
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
RAB31 RAB31, member RAS oncogene family
RASAL1 RAS protein activator like 1 (GAP1 like)
RB1 retinoblastoma 1
REC8 REC8 meiotic recombination protein
RGS14 regulator of G-protein signaling 14
RHOBTB3 Rho-related BTB domain containing 3
RNF39 ring finger protein 39
RNGTT RNA guanylyltransferase and 5'-phosphatase
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SAMD4A sterile alpha motif domain containing 4A
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SDF4 stromal cell derived factor 4
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SIGLEC6 sialic acid binding Ig-like lectin 6
SIT1 signaling threshold regulating transmembrane adaptor 1
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SMAD4 SMAD family member 4
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SPIDR scaffolding protein involved in DNA repair
TADA2A transcriptional adaptor 2A
TEX13A testis expressed 13A
THBD thrombomodulin
TMEM63A transmembrane protein 63A
TNPO2 transportin 2
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
TSPAN1 tetraspanin 1
TSPAN8 tetraspanin 8
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
VARS valyl-tRNA synthetase
WNK1 WNK lysine deficient protein kinase 1
ZFPL1 zinc finger protein-like 1
ZNF552 zinc finger protein 552

decreased expression

Symbol Name
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
AGMAT agmatine ureohydrolase (agmatinase)
ALOX15B arachidonate 15-lipoxygenase, type B
ALPK1 alpha-kinase 1
ARHGAP22 Rho GTPase activating protein 22
ATAD5 ATPase family, AAA domain containing 5
AXIN1 axin 1
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BFSP1 beaded filament structural protein 1, filensin
BMP15 bone morphogenetic protein 15
BST1 bone marrow stromal cell antigen 1
C5ORF45 chromosome 5 open reading frame 45
CA9 carbonic anhydrase IX
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CASZ1 castor zinc finger 1
CCNO cyclin O
CD70 CD70 molecule
CENPO centromere protein O
CIDEB cell death-inducing DFFA-like effector b
COG4 component of oligomeric golgi complex 4
CRMP1 collapsin response mediator protein 1
CTSK cathepsin K
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DBF4B DBF4 zinc finger B
DCAF13 DDB1 and CUL4 associated factor 13
DNAH17 dynein, axonemal, heavy chain 17
DNM3 dynamin 3
ENOX1 ecto-NOX disulfide-thiol exchanger 1
EPN1 epsin 1
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM110B family with sequence similarity 110, member B
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
GJA9 gap junction protein, alpha 9, 59kDa
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GRM4 glutamate receptor, metabotropic 4
HIST1H2AJ histone cluster 1, H2aj
HIST1H3B histone cluster 1, H3b
HIST1H3C histone cluster 1, H3c
HIST2H2AA3 histone cluster 2, H2aa3
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGB7 integrin, beta 7
KCTD17 potassium channel tetramerization domain containing 17
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KLHL28 kelch-like family member 28
LATS1 large tumor suppressor kinase 1
LIME1 Lck interacting transmembrane adaptor 1
LINC00260 long intergenic non-protein coding RNA 260
LINC00597 long intergenic non-protein coding RNA 597
LRRC15 leucine rich repeat containing 15
MAP3K7CL MAP3K7 C-terminal like
MMP10 matrix metallopeptidase 10
MNMIP1 manchette microtubule inner protein 1
MTSS1L metastasis suppressor 1-like
MYO1F myosin IF
NKX3-2 NK3 homeobox 2
NOL12 nucleolar protein 12
PLBD1 phospholipase B domain containing 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
POLL polymerase (DNA directed), lambda
POMT2 protein-O-mannosyltransferase 2
PRB3 proline-rich protein BstNI subfamily 3
PRSS53 protease, serine, 53
RNF126P1 ring finger protein 126 pseudogene 1
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
S100A3 S100 calcium binding protein A3
SAYSD1 SAYSVFN motif domain containing 1
SCGB2A2 secretoglobin, family 2A, member 2
SECISBP2 SECIS binding protein 2
SH3GLB2 SH3-domain GRB2-like endophilin B2
SLAMF7 SLAM family member 7
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC25A40 solute carrier family 25, member 40
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SND1-IT1 SND1 intronic transcript 1
STAB2 stabilin 2
STARD3 StAR-related lipid transfer (START) domain containing 3
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TAOK1 TAO kinase 1
TBC1D17 TBC1 domain family, member 17
TSNAXIP1 translin-associated factor X interacting protein 1
TTLL1 tubulin tyrosine ligase-like family member 1
VGLL3 vestigial-like family member 3
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF222 zinc finger protein 222
ZNF268 zinc finger protein 268
ZNF37BP zinc finger protein 37B, pseudogene
ZNF480 zinc finger protein 480
ZNF667 zinc finger protein 667
ZXDB zinc finger, X-linked, duplicated B