| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the sisomicin-4132 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACO2 | aconitase 2, mitochondrial |
| ADAM20 | ADAM metallopeptidase domain 20 |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADRA1A | adrenoceptor alpha 1A |
| AFF1 | AF4/FMR2 family, member 1 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| AQP4 | aquaporin 4 |
| ATXN2L | ataxin 2-like |
| BICC1 | BicC family RNA binding protein 1 |
| CA9 | carbonic anhydrase IX |
| CADM4 | cell adhesion molecule 4 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CCDC40 | coiled-coil domain containing 40 |
| CD160 | CD160 molecule |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| COL1A1 | collagen, type I, alpha 1 |
| CRY2 | cryptochrome circadian clock 2 |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CYTH4 | cytohesin 4 |
| DCTN2 | dynactin 2 (p50) |
| DIAPH2-AS1 | DIAPH2 antisense RNA 1 |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DYM | dymeclin |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A |
| ELL2 | elongation factor, RNA polymerase II, 2 |
| FAM212B | family with sequence similarity 212, member B |
| FBLN1 | fibulin 1 |
| FBXO40 | F-box protein 40 |
| GGT1 | gamma-glutamyltransferase 1 |
| GPR22 | G protein-coupled receptor 22 |
| GPR85 | G protein-coupled receptor 85 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| HCN2 | hyperpolarization activated cyclic nucleotide gated potassium channel 2 |
| HFE | hemochromatosis |
| HIST1H3E | histone cluster 1, H3e |
| HIST1H3I | histone cluster 1, H3i |
| HOXB5 | homeobox B5 |
| ICAM1 | intercellular adhesion molecule 1 |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| ITGB6 | integrin, beta 6 |
| JAM3 | junctional adhesion molecule 3 |
| KIF21B | kinesin family member 21B |
| KIR2DL3 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 |
| KIR2DS1 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 |
| KLF12 | Kruppel-like factor 12 |
| LAMB4 | laminin, beta 4 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LMTK1 | lemur tail kinase 1 |
| LPAR1 | lysophosphatidic acid receptor 1 |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAL | mal, T-cell differentiation protein |
| METTL7A | methyltransferase like 7A |
| NDN | necdin, melanoma antigen (MAGE) family member |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NTM | neurotrimin |
| OCM2 | oncomodulin 2 |
| OR10H3 | olfactory receptor, family 10, subfamily H, member 3 |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 |
| PARG | poly (ADP-ribose) glycohydrolase |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PLEK | pleckstrin |
| POLM | polymerase (DNA directed), mu |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PTAFR | platelet-activating factor receptor |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RAB3GAP2 | RAB3 GTPase activating protein subunit 2 (non-catalytic) |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 |
| REPS1 | RALBP1 associated Eps domain containing 1 |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| RSU1 | Ras suppressor protein 1 |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SH2D2A | SH2 domain containing 2A |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
| SLCO1C1 | solute carrier organic anion transporter family, member 1C1 |
| SSTR2 | somatostatin receptor 2 |
| TBX5 | T-box 5 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TG | thyroglobulin |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TP63 | tumor protein p63 |
| TRD | T cell receptor delta locus |
| TRIM68 | tripartite motif containing 68 |
| TSPAN9 | tetraspanin 9 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF155 | zinc finger protein 155 |
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ACTL8 | actin-like 8 |
| APOD | apolipoprotein D |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| B9D2 | B9 protein domain 2 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C5AR1 | complement component 5a receptor 1 |
| CCDC132 | coiled-coil domain containing 132 |
| CCDC69 | coiled-coil domain containing 69 |
| CD53 | CD53 molecule |
| CD82 | CD82 molecule |
| CEL | carboxyl ester lipase |
| CLCA1 | chloride channel accessory 1 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DSPP | dentin sialophosphoprotein |
| DYSF | dysferlin |
| EHBP1L1 | EH domain binding protein 1-like 1 |
| ENO2 | enolase 2 (gamma, neuronal) |
| EPX | eosinophil peroxidase |
| FADS2 | fatty acid desaturase 2 |
| FAM46C | family with sequence similarity 46, member C |
| FBXO31 | F-box protein 31 |
| FGF13 | fibroblast growth factor 13 |
| FLJ21369 | uncharacterized protein FLJ21369 |
| FMOD | fibromodulin |
| FRAT1 | frequently rearranged in advanced T-cell lymphomas 1 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GPR19 | G protein-coupled receptor 19 |
| HCFC1 | host cell factor C1 |
| HIST1H2AK | histone cluster 1, H2ak |
| HMOX1 | heme oxygenase 1 |
| IL4R | interleukin 4 receptor |
| INO80D | INO80 complex subunit D |
| INPP5B | inositol polyphosphate-5-phosphatase, 75kDa |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNK10 | potassium channel, two pore domain subfamily K, member 10 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
| KLF1 | Kruppel-like factor 1 (erythroid) |
| KLHL25 | kelch-like family member 25 |
| LAMP3 | lysosomal-associated membrane protein 3 |
| LEFTY1 | left-right determination factor 1 |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MGC2889 | uncharacterized protein MGC2889 |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MST1 | macrophage stimulating 1 |
| NEUROD4 | neuronal differentiation 4 |
| NIPAL2 | NIPA-like domain containing 2 |
| NME5 | NME/NM23 family member 5 |
| PCBP4 | poly(rC) binding protein 4 |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLD3 | phospholipase D family, member 3 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PTPRM | protein tyrosine phosphatase, receptor type, M |
| PXN | paxillin |
| RAB36 | RAB36, member RAS oncogene family |
| RHBDD3 | rhomboid domain containing 3 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC2A11 | solute carrier family 2 (facilitated glucose transporter), member 11 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| TBC1D19 | TBC1 domain family, member 19 |
| TBX19 | T-box 19 |
| TCP10 | t-complex 10 |
| TLR5 | toll-like receptor 5 |
| TMEM180 | transmembrane protein 180 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| UBQLN4 | ubiquilin 4 |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| VEGFB | vascular endothelial growth factor B |
| VIM | vimentin |
| VWA1 | von Willebrand factor A domain containing 1 |
| ZNF230 | zinc finger protein 230 |
| ZNF329 | zinc finger protein 329 |
| ZNF34 | zinc finger protein 34 |
