site of double-strand break Gene Set

Dataset GO Cellular Component Annotations
Category structural or functional annotations
Type cellular component
Description A region of a chromosome at which a DNA double-strand break has occurred. DNA damage signaling and repair proteins accumulate at the lesion to respond to the damage and repair the DNA to form a continuous DNA helix. (Gene Ontology, GO_0035861)
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21 proteins localized to the site of double-strand break cellular component from the curated GO Cellular Component Annotations dataset.

Symbol Name
APLF aprataxin and PNKP like factor
ATF2 activating transcription factor 2
ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2
H2AFX H2A histone family, member X
HUS1 HUS1 checkpoint homolog (S. pombe)
HUS1B HUS1 checkpoint homolog b (S. pombe)
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
NBN nibrin
PARP3 poly (ADP-ribose) polymerase family, member 3
PHF1 PHD finger protein 1
PRPF19 pre-mRNA processing factor 19
RAD50 RAD50 homolog (S. cerevisiae)
RFWD3 ring finger and WD repeat domain 3
RNF168 ring finger protein 168, E3 ubiquitin protein ligase
RNF169 ring finger protein 169
RNF8 ring finger protein 8, E3 ubiquitin protein ligase
RPA2 replication protein A2, 32kDa
SETMAR SET domain and mariner transposase fusion gene
SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
VCP valosin containing protein