| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the sitosterol-4073 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| ADH7 | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide |
| ANGPTL2 | angiopoietin-like 2 |
| APOBEC3F | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F |
| APOL3 | apolipoprotein L, 3 |
| ATP6V0A4 | ATPase, H+ transporting, lysosomal V0 subunit a4 |
| BCHE | butyrylcholinesterase |
| BET1L | Bet1 golgi vesicular membrane trafficking protein-like |
| BHMT2 | betaine--homocysteine S-methyltransferase 2 |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| C4BPA | complement component 4 binding protein, alpha |
| CADM1 | cell adhesion molecule 1 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CCL23 | chemokine (C-C motif) ligand 23 |
| CCNK | cyclin K |
| CD53 | CD53 molecule |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
| CEP295 | centrosomal protein 295kDa |
| CHRNB3 | cholinergic receptor, nicotinic, beta 3 (neuronal) |
| CHST5 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 |
| CLUL1 | clusterin-like 1 (retinal) |
| DICER1 | dicer 1, ribonuclease type III |
| DNPH1 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 |
| DOK4 | docking protein 4 |
| DPY19L1P1 | DPY19L1 pseudogene 1 |
| EBF2 | early B-cell factor 2 |
| EMX1 | empty spiracles homeobox 1 |
| ERCC4 | excision repair cross-complementation group 4 |
| FGB | fibrinogen beta chain |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like |
| IGFBP7 | insulin-like growth factor binding protein 7 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KDM7A | lysine (K)-specific demethylase 7A |
| KLHL22 | kelch-like family member 22 |
| KRT16 | keratin 16, type I |
| LIG3 | ligase III, DNA, ATP-dependent |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LPAL2 | lipoprotein, Lp(a)-like 2, pseudogene |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
| MAP2K7 | mitogen-activated protein kinase kinase 7 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| MMP10 | matrix metallopeptidase 10 |
| MT4 | metallothionein 4 |
| MYBPC3 | myosin binding protein C, cardiac |
| NCF4 | neutrophil cytosolic factor 4, 40kDa |
| NDN | necdin, melanoma antigen (MAGE) family member |
| NPAS3 | neuronal PAS domain protein 3 |
| NUP88 | nucleoporin 88kDa |
| PAEP | progestagen-associated endometrial protein |
| PAWR | PRKC, apoptosis, WT1, regulator |
| PAX8 | paired box 8 |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated |
| PDE4A | phosphodiesterase 4A, cAMP-specific |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PHTF2 | putative homeodomain transcription factor 2 |
| PML | promyelocytic leukemia |
| PNLIPRP1 | pancreatic lipase-related protein 1 |
| PON1 | paraoxonase 1 |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta |
| PRDM1 | PR domain containing 1, with ZNF domain |
| PRKCI | protein kinase C, iota |
| PRR5 | proline rich 5 (renal) |
| PTBP3 | polypyrimidine tract binding protein 3 |
| RANBP1 | RAN binding protein 1 |
| RBM26 | RNA binding motif protein 26 |
| RCE1 | Ras converting CAAX endopeptidase 1 |
| RCHY1 | ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| SELP | selectin P (granule membrane protein 140kDa, antigen CD62) |
| SEMA6B | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) |
| SLCO5A1 | solute carrier organic anion transporter family, member 5A1 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SMAD5 | SMAD family member 5 |
| SOX21 | SRY (sex determining region Y)-box 21 |
| SPOCK3 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 |
| STAT4 | signal transducer and activator of transcription 4 |
| SYNM | synemin, intermediate filament protein |
| TBC1D2 | TBC1 domain family, member 2 |
| TBX1 | T-box 1 |
| TCP10 | t-complex 10 |
| TRIM15 | tripartite motif containing 15 |
| TRPM8 | transient receptor potential cation channel, subfamily M, member 8 |
| UCP1 | uncoupling protein 1 (mitochondrial, proton carrier) |
| UGT2B4 | UDP glucuronosyltransferase 2 family, polypeptide B4 |
| WNT8B | wingless-type MMTV integration site family, member 8B |
| ZNF155 | zinc finger protein 155 |
| Symbol | Name |
|---|---|
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| AOC2 | amine oxidase, copper containing 2 (retina-specific) |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARR3 | arrestin 3, retinal (X-arrestin) |
| ASTN1 | astrotactin 1 |
| BCL2L2 | BCL2-like 2 |
| BMP10 | bone morphogenetic protein 10 |
| BTD | biotinidase |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CD68 | CD68 molecule |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CNN1 | calponin 1, basic, smooth muscle |
| CNTLN | centlein, centrosomal protein |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| DPYS | dihydropyrimidinase |
| EFCAB2 | EF-hand calcium binding domain 2 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM120C | family with sequence similarity 120C |
| FAM222B | family with sequence similarity 222, member B |
| FBXO22 | F-box protein 22 |
| FMO4 | flavin containing monooxygenase 4 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GPR1 | G protein-coupled receptor 1 |
| GRAMD4 | GRAM domain containing 4 |
| GRTP1 | growth hormone regulated TBC protein 1 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HAMP | hepcidin antimicrobial peptide |
| HIST1H1D | histone cluster 1, H1d |
| IBA57 | IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) |
| IFT140 | intraflagellar transport 140 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KIAA0319L | KIAA0319-like |
| KIAA1462 | KIAA1462 |
| KIFC3 | kinesin family member C3 |
| KLF3 | Kruppel-like factor 3 (basic) |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LOC729164 | hCG1732469 |
| LOC730101 | uncharacterized LOC730101 |
| LPPR1 | lipid phosphate phosphatase-related protein type 1 |
| LRP4 | low density lipoprotein receptor-related protein 4 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MAPK12 | mitogen-activated protein kinase 12 |
| METTL16 | methyltransferase like 16 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MMP2 | matrix metallopeptidase 2 |
| MTCP1 | mature T-cell proliferation 1 |
| MYLK | myosin light chain kinase |
| NADSYN1 | NAD synthetase 1 |
| NAG18 | NAG18 mRNA |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OSR2 | odd-skipped related transciption factor 2 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PADI1 | peptidyl arginine deiminase, type I |
| PCDHGA10 | protocadherin gamma subfamily A, 10 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PLD3 | phospholipase D family, member 3 |
| PTGES2 | prostaglandin E synthase 2 |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAPSN | receptor-associated protein of the synapse |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SELL | selectin L |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 |
| SLC6A20 | solute carrier family 6 (proline IMINO transporter), member 20 |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| SSTR4 | somatostatin receptor 4 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STMN4 | stathmin-like 4 |
| THSD4 | thrombospondin, type I, domain containing 4 |
| TMEM120B | transmembrane protein 120B |
| TMEM212 | transmembrane protein 212 |
| TMEM53 | transmembrane protein 53 |
| TRIM25 | tripartite motif containing 25 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TSC22D4 | TSC22 domain family, member 4 |
| TUBA3C | tubulin, alpha 3c |
| TUBA4B | tubulin, alpha 4b |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZNF268 | zinc finger protein 268 |
| ZNF358 | zinc finger protein 358 |
| ZNF702P | zinc finger protein 702, pseudogene |
| ZNF76 | zinc finger protein 76 |
