| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the sitosterol-4154 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ACSM5 | acyl-CoA synthetase medium-chain family member 5 |
| AK2 | adenylate kinase 2 |
| ANK2 | ankyrin 2, neuronal |
| ATP10B | ATPase, class V, type 10B |
| BTN2A3P | butyrophilin, subfamily 2, member A3, pseudogene |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CCDC81 | coiled-coil domain containing 81 |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CFDP1 | craniofacial development protein 1 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CRLF2 | cytokine receptor-like factor 2 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| CYTH4 | cytohesin 4 |
| DMRT1 | doublesex and mab-3 related transcription factor 1 |
| DOCK6 | dedicator of cytokinesis 6 |
| DPF1 | D4, zinc and double PHD fingers family 1 |
| DTNB | dystrobrevin, beta |
| DVL2 | dishevelled segment polarity protein 2 |
| EDA | ectodysplasin A |
| EGR2 | early growth response 2 |
| ELF5 | E74-like factor 5 (ets domain transcription factor) |
| ELL2 | elongation factor, RNA polymerase II, 2 |
| EPYC | epiphycan |
| FCMR | Fc fragment of IgM receptor |
| FGF6 | fibroblast growth factor 6 |
| FLOT1 | flotillin 1 |
| FOXG1 | forkhead box G1 |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GHRHR | growth hormone releasing hormone receptor |
| GLB1L | galactosidase, beta 1-like |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like |
| GRIP2 | glutamate receptor interacting protein 2 |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| IFNW1 | interferon, omega 1 |
| JMJD6 | jumonji domain containing 6 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KLK7 | kallikrein-related peptidase 7 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| KRT17 | keratin 17, type I |
| KRT32 | keratin 32, type I |
| LAMB4 | laminin, beta 4 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| MAOA | monoamine oxidase A |
| MAPK11 | mitogen-activated protein kinase 11 |
| MAPK7 | mitogen-activated protein kinase 7 |
| MCTP1 | multiple C2 domains, transmembrane 1 |
| MED18 | mediator complex subunit 18 |
| MID1 | midline 1 |
| MIP | major intrinsic protein of lens fiber |
| MXD4 | MAX dimerization protein 4 |
| MYO1B | myosin IB |
| NPR1 | natriuretic peptide receptor 1 |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 |
| OMD | osteomodulin |
| OR1G1 | olfactory receptor, family 1, subfamily G, member 1 |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| PADI3 | peptidyl arginine deiminase, type III |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 |
| PARVB | parvin, beta |
| PKN2 | protein kinase N2 |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) |
| PLK3 | polo-like kinase 3 |
| PPP1R37 | protein phosphatase 1, regulatory subunit 37 |
| PRPH2 | peripherin 2 (retinal degeneration, slow) |
| PSMB2 | proteasome (prosome, macropain) subunit, beta type, 2 |
| RABGAP1 | RAB GTPase activating protein 1 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| RPL10 | ribosomal protein L10 |
| RUNX1 | runt-related transcription factor 1 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) |
| SCN5A | sodium channel, voltage gated, type V alpha subunit |
| SDHD | succinate dehydrogenase complex, subunit D, integral membrane protein |
| SH3GL3 | SH3-domain GRB2-like 3 |
| SLC16A4 | solute carrier family 16, member 4 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SNED1 | sushi, nidogen and EGF-like domains 1 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 |
| SULT2A1 | sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 |
| TAAR5 | trace amine associated receptor 5 |
| TEP1 | telomerase-associated protein 1 |
| THBS1 | thrombospondin 1 |
| THRB | thyroid hormone receptor, beta |
| TPSG1 | tryptase gamma 1 |
| TTC39A | tetratricopeptide repeat domain 39A |
| USP22 | ubiquitin specific peptidase 22 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZBTB43 | zinc finger and BTB domain containing 43 |
| ZNF407 | zinc finger protein 407 |
| ZNF652 | zinc finger protein 652 |
| ZNF702P | zinc finger protein 702, pseudogene |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ACTL8 | actin-like 8 |
| ADCK4 | aarF domain containing kinase 4 |
| AFAP1 | actin filament associated protein 1 |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| ALS2CL | ALS2 C-terminal like |
| AMT | aminomethyltransferase |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| ARMC4 | armadillo repeat containing 4 |
| ATP6V0A4 | ATPase, H+ transporting, lysosomal V0 subunit a4 |
| BCL9 | B-cell CLL/lymphoma 9 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CAMTA1 | calmodulin binding transcription activator 1 |
| CCDC121 | coiled-coil domain containing 121 |
| CCDC68 | coiled-coil domain containing 68 |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CLDND1 | claudin domain containing 1 |
| CUL9 | cullin 9 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DBF4B | DBF4 zinc finger B |
| ENO3 | enolase 3 (beta, muscle) |
| FAM186A | family with sequence similarity 186, member A |
| FBXO2 | F-box protein 2 |
| FILIP1L | filamin A interacting protein 1-like |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FLJ22184 | |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GPR157 | G protein-coupled receptor 157 |
| GPRC5D | G protein-coupled receptor, class C, group 5, member D |
| GRPR | gastrin-releasing peptide receptor |
| HDAC11 | histone deacetylase 11 |
| HIST1H2AI | histone cluster 1, H2ai |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HYI | hydroxypyruvate isomerase (putative) |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KCNQ3 | potassium channel, voltage gated KQT-like subfamily Q, member 3 |
| KIAA0754 | KIAA0754 |
| KLF3 | Kruppel-like factor 3 (basic) |
| LHX1 | LIM homeobox 1 |
| LOC257152 | uncharacterized LOC257152 |
| LRRC61 | leucine rich repeat containing 61 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MCOLN1 | mucolipin 1 |
| MDM4 | MDM4, p53 regulator |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| NDE1 | nudE neurodevelopment protein 1 |
| NDOR1 | NADPH dependent diflavin oxidoreductase 1 |
| NECAP2 | NECAP endocytosis associated 2 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| PADI1 | peptidyl arginine deiminase, type I |
| PARG | poly (ADP-ribose) glycohydrolase |
| PCDHB3 | protocadherin beta 3 |
| PGPEP1 | pyroglutamyl-peptidase I |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| POMT2 | protein-O-mannosyltransferase 2 |
| POPDC3 | popeye domain containing 3 |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| PXN | paxillin |
| RNF39 | ring finger protein 39 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) |
| RPAP1 | RNA polymerase II associated protein 1 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SIX1 | SIX homeobox 1 |
| SKI | SKI proto-oncogene |
| SLC52A1 | solute carrier family 52 (riboflavin transporter), member 1 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| STK16 | serine/threonine kinase 16 |
| SYNC | syncoilin, intermediate filament protein |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TET3 | tet methylcytosine dioxygenase 3 |
| THBS3 | thrombospondin 3 |
| TNRC6B | trinucleotide repeat containing 6B |
| TPCN1 | two pore segment channel 1 |
| TRAIP | TRAF interacting protein |
| UPK3B | uroplakin 3B |
| VGF | VGF nerve growth factor inducible |
| WDR33 | WD repeat domain 33 |
| WDR4 | WD repeat domain 4 |
| XYLT2 | xylosyltransferase II |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZNF532 | zinc finger protein 532 |
| ZNF580 | zinc finger protein 580 |
| ZNF750 | zinc finger protein 750 |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |
